THERE S MORE TO GAIN.

Transcription

1 THERE S MORE TO GAIN.

2 YOUR SUCCESS DEPENDS ON YOUR GAINS. Your operation is all about gain. More average daily gain. Greater gains in feed efficiency. And tangible gains in cattle health. All of which help boost your bottom line. So why let limited feed additive choices or technologies hold you back? With Zoetis, you gain: More choices with the broadest range of feed additives on the market More efficiency to maximize performance from starting to finishing cattle More support with production specialists and nutritionists who can tailor solutions to your operation More profits by enhancing cattle health and maximizing feed efficiency and weight gains ACTOGAIN 45 (ractopamine hydrochloride) Feeding ACTOGAIN 45 in the last 28 to 42 days allows energy to be redirected to make more lean muscle and less fat, resulting in: Increased rate of weight gain Improved feed efficiency Increased carcass leanness* In a study with more than 1,200 steers, cattle fed ACTOGAIN in the last 34 days demonstrated a dramatic increase in feed efficiency and carcass weight gain versus other feed additive combinations Final Avg. Body Weight (lb.) 0.5 Cattle Avg. Daily Gain (lb./day) 6.2 Pounds of Feed per Pound of Gain 835 Hot Carcass Weight ACTOGAIN ACTOGAIN + RUMENSIN + TYLAN RUMENSIN + TYLAN *When fed as a complete feed

3 AUREOMYCIN TYPE A MEDICATED ARTICLE (chlortetracycline) AUREOMYCIN controls and treats bacterial pneumonia, controls anaplasmosis, treats bacterial enteritis and reduces the incidence of liver abscesses. A study examined the effect of feeding AUREOMYCIN in a five-day course of therapy for the treatment of bacterial pneumonia after arrival at the feedlot versus feeding a ration alone. 9 Cattle fed AUREOMYCIN demonstrated: Reduced morbidity, which decreased the need for use of antibiotics in the treatment of bovine respiratory disease. 9 Reduction of antibiotics, such as macrolides and fluoroquinolones that were deemed critically more important under FDA Guidance 152, is important in an overall responsible use plan. Chlortetracycline is considered in the lower category of medically important antibiotics. Two other studies examined the impact of chlortetracycline feeding upon resistance emergence in samples from the digestive tract under conditions and feeding periods common to current cattle husbandry practices. The presence of antibiotic-resistant genes did not differ between cattle treated with chlortetracycline and untreated cattle. 10,11 Caution: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. AUREO S 700 TYPE A MEDICATED ARTICLE (chlortetracycline/sulfamethazine) This 28-day therapy helps newly weaned, stressed or incoming cattle maintain weight gain in the face of respiratory disease. In a feedlot study, cattle fed AUREO S 700 during the first 28 days demonstrated statistically less morbidity (p = ), chronic illness (p = ) and a trend to less mortality (p = ) when compared with cattle receiving a conventional ration alone AUREO S 700 FEED ONLY 0 BRD Morbidity Rate 0.75 Total Chronics 0.2 Total Mortality Rate Caution: Federal law restricts medicated feed containing this VFD drug to use by or on the order of a licensed veterinarian. BOVATEC (lasalocid sodium) BOVATEC boosts feed efficiency, increases rate of weight gain and controls coccidiosis, but unlike Rumensin, it: Requires no step-up program Is approved for feeding in combination with AUREOMYCIN Won t compromise feed intake 3-6* A large pen study demonstrated that cattle fed BOVATEC showed equal feed efficiency to those fed Rumensin, but had significantly greater total gains (p > 0.05), average daily gains (ADG) (p > 0.05) and feed intake (p < 0.05), especially for starting cattle BOVATEC + AUREOMYCIN RUMENSIN + TYLAN **Carcass adjusted 790 Total Gain (lb.)** 3.75 ADG (lb.)** 18 Average Daily Feed Intake (lb. DM) When BOVATEC is fed in combination with AUREOMYCIN, a veterinary feed directive is required. *Research shows BOVATEC compromised feed intake compared to no ionophore, but BOVATEC still encourages a significantly higher feed intake than Rumensin.

4 CATTLYST (laidlomycin propionate potassium) Studies have demonstrated CATTLYST helps improve feed efficiency and delivers superior weight gains to Rumensin, 7,8 without the need for a step-up program. A pooled analysis showed that compared with cattle fed Rumensin and Tylan, those fed CATTLYST with AUREOMYCIN to help control BRD delivered: lb. live weight +8.7 lb. hot carcass weight Results from a meta-analysis showed that compared with steers fed Rumensin, with or without Tylan, those fed CATTLYST, with or without AUREOMYCIN, demonstrated: lb. hot carcass weight lb. ADG lb./day feed intake When CATTLYST is fed in combination with AUREOMYCIN, a veterinary feed directive is required. DECCOX (decoquinate) As a nonantibiotic feed additive, DECCOX helps prevent coccidiosis in cattle that often have compromised immune systems. In a field trial, compared with heifers fed their ration alone, those fed DECCOX demonstrated: 14 No signs of scouring vs. 70% of control calves with signs of scouring Because DECCOX helped reduce scouring, calves demonstrated: pounds of total gain lb./day LB. TOTAL GAIN MGA (melengestrol acetate) It s the only feed additive that suppresses heat in feedlot heifers while improving feed efficiency and increasing weight gain. In a study, heifers were fed MGA or their ration alone from Day 28 to slaughter. Those fed MGA demonstrated: lb./head +19 lb. carcass weight

5 MORE FEED ADDITIVES TO FIT YOUR UNIQUE NEEDS No other animal health supplier offers you a broader range of cattle feed additives to help you achieve better health and performance in your operation. ACTOGAIN 45/BETA AGONIST Boosts average daily gain, improves feed efficiency and increases carcass leanness during the last 30 days on feed, when cattle are most inefficient INDICATIONS COMBINATION APPROVALS* MGA, Rumensin (monensin) and Tylan (tylosin phosphate) or Tylovet (tylosin tartrate) Rumensin and Tylan AUREOMYCIN TYPE A MEDICATED ARTICLE/ANTIBIOTIC FEED ADDITIVE The beef industry s No. 1 chlortetracycline, 2 it controls and treats bovine respiratory disease (BRD), controls anaplasmosis and treats bacterial enteritis (VFD Required) Health BOVATEC CATTLYST DECCOX AUREO S 700 TYPE A MEDICATED ARTICLE/ ANTIBIOTIC FEED ADDITIVE A 28-day therapy to help stressed, incoming or newly weaned calves maintain weight gain in the face of respiratory disease (VFD Required) Health N/A BOVATEC /IONOPHORE Boosts feed efficiency and, unlike Rumensin, delivers superior intake and average daily gain without compromising feed intake 3-6 AUREOMYCIN MGA Oxytetracycline MGA and Tylan CATTLYST /IONOPHORE Delivers feed efficiency and greater weight gains than Rumensin, 7,8 without the need for a step-up program AUREOMYCIN DECCOX /COCCIDIOSTAT Nonantibiotic feed additive used to help prevent coccidiosis in cattle that often have compromised immune systems Health AUREOMYCIN CHLORMAX Rumensin Rumensin and Tylan MGA /ESTRUS SUPPRESSOR The only feed additive that suppresses heat in feedlot heifers while improving feed efficiency and increasing weight gain *Combinations with AUREOMYCIN, CHLORMAX, Tylan, oxytetracycline or Tylovet require a valid veterinary feed directive. Estrus Suppression ACTOGAIN, Rumensin and Tylan BOVATEC Rumensin, Tylan and Optaflexx (ractopamine hydrochloride) Oxytetracycline Rumensin Rumensin and Tylan

6 COUNT ON THE INDUSTRY S LARGEST SUPPORT TEAM You can rely on Zoetis as a resource to help improve your operation s health and productivity. With a team of livestock production specialists and nutritionists, Zoetis can help tailor a feeding program to your operation and help you successfully implement veterinary feed directives (VFDs) when needed. There is a lot to gain with Feed Additive Solutions from Zoetis. Talk to your nutritionist or Zoetis representative or visit CattleFeedAdditives.com. IMPORTANT SAFETY INFORMATION: Do not use ACTOGAIN in animals intended for breeding. Refer to label for complete directions for use, precautions, and warnings. Withdraw AUREO S 700 seven (7) days prior to slaughter. Do not use in calves to be processed for veal. Do not use AUREOMYCIN in calves to be processed for veal. Do not use DECCOX in cows producing milk for human consumption. Do not allow horses or other equines access to feeds containing CATTLYST. Do not use in animals intended for breeding. Do not use BOVATEC in calves to be processed for veal. Do not allow horses or other equines access to feeds containing lasalocid, as ingestion may be fatal. Feeding undiluted or mixing errors resulting in excessive concentrations of lasalocid could be fatal to cattle and sheep. Data on file, Study Report No. A131R-US , Zoetis Inc. Animalytix data, November 2017, Zoetis Inc. Data on file. Zoetis Trial MC AULA13 (Colorado study), Zoetis Inc. 4 Data on file. Zoetis Trial MC AULA13 (Oklahoma study), Zoetis Inc. 5 Data on file. MC AULA13 (South Dakota study), Zoetis Inc. 6 Data on file. Zoetis Trial MC AULA13 (New Mexico study), Zoetis Inc. 7 Reinhardt C. The Effects of Cattlyst + Aureomycin vs Rumensin + Tylan in Finishing Cattle on Feedlot, Carcass Traits, and Incidence of Liver Abscesses: a Pooled Analysis of Seven Studies market research study, Zoetis Inc. 8 Cernicchiaro N, Corbin M, Quinn M, Prouty F, Branine M, Renter DG. Meta-analysis of the effects of laidlomycin propionate, fed alone or in combination with chlortetracycline, compared with monensin sodium, fed alone or in combination with tylosin, on growth performance, health, and carcass outcomes in finishing steers in North America. J Anim Sci. 2016;94(4): Data on file, Study Report No. 17CRGMFA-01-01, Zoetis Inc. 10 Miller E, Vikram A, Agga GE, Arthur TM, Schmidt JW. Effects of In-Feed Chlortetracycline Prophylaxis in Beef Cattle on Antimicrobial Resistance Genes. Foodborne Pathogens and Disease. 2018;15(11) 11 Agga GE, Schmidt JW, Arthur TM. Effects of In-Feed Chlortetracycline Prophylaxis in Beef Cattle on Animal Health and Antimicrobial-Resistant Escherichia coli. Applied and Environmental Microbiology. DOI: /AEM Gallo GF, Berg JL. Efficacy of a feed-additive antibacterial combination for improving feedlot cattle performance and health. Can Vet J. 1995;36(4): Data on file, Study Report No. A131R-US , Zoetis Inc. 14 Data on file, Study Report No. AR-00269, Zoetis Inc. 15 Perrett T, Wildman BK, Jim GK, et al. Evaluation of the efficacy and cost-effectiveness of melengestrol acetate in feedlot heifer calves in western Canada. Vet Ther. 2008;9(3): All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. Optaflexx, Rumensin and Tylan are registered trademarks of Eli Lilly and Company, its subsidiaries or affiliates. Tylovet is a registered trademark of Huvepharma AD. Animalytix is a registered trademark of ALYX Zoetis Inc. All rights reserved. ASM-00012R1