R&D trends in Crop Protection

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Patience Powers
5 years ago
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1 R&D trends in Crop Protection Phillips McDougall Vineyard Business Centre Saughland Pathhead Midlothian EH37 5XP Tel : phillipsmcdougall@dial.pipex.com 1

2 Industry background 2

3 Year Market Performance 2011 (Distributor level average exchange rates - Nominal US$) ABIM Conference Crop Non-Crop GM Conventional Protection Agrochemicals Seed Seed ($m) ($m) ($m) ($m) /2010 % Agrochemicals = $50, % 3 Seed= $34, %

4 R&D in Crop Protection and Production 4

5 Cost of Bringing a New Product to Market $m Registration 300 Total $256 m. Environmental Chemistry Toxicology Total $152 m Development 67 Research 72 Total $184 m Development 79 Research Development 146 Research 85 Field Trials Chemistry Tox/Env Chemistry Biology Chemistry Results of Study undertaken for ECPA and CropLife America 5

6 Cost of Bringing a New Product to Market Agrochemical Plant biotechnology trait $ million Development Research 0 Total = $256 m Registration Environmental Chemistry Toxicology Field Trials Chemistry Tox/Env chemistry Biology Chemistry $ million Total = $136 m Registration & Regulatory Affairs Regulatory Science Introgression breeding & testing Commercial event production Construct optimisation Late discovery Early Discovery Agrochemical Crop Biotech trait Agrochemical costs based on 2009 Crop Life America/ECPA study Plant biotechnology trait costs based on 2011 Crop Life International study 6

7 No. of Agrochemical Products Processed Leading to a Successful Product Launch Research Synthesis Development Registration Results of Study undertaken for ECPA and CropLife America 7

8 Number of Units Associated with Biotech Trait R&D Process Activity Stage For an Event introduced between Mean Number of Units Evaluated I Early Discovery 6204 II Late Discovery 4005 III Construct Optimisation 511 IV Commercial Event Production & selection V Introgression Breeding & Wide Area Testing VI Regulatory Science 1 VII Registration & regulatory Affairs 1 8

9 Time from New Product Inception to First Introduction (1) Agrochemical ABIM Conference Number of years between the first synthesis and the first sale of the product Results of Study undertaken for ECPA and CropLife America (2) Plant biotechnology trait Number of years from discovery of trait to first commercial sale Canola Corn Cotton Soybean All crops Results of Study undertaken for CropLife International 9

Agrochemical Industry R&D Expenditure by Function (Fourteen Reporting Companies Only) 2007 2012 ABIM Conference Product Monitoring

6% Development of Generics 1.8% Development of Generics 1.9% Post Launch Development 31.1% Development of New a.i. 23.

10 Agrochemical Industry R&D Expenditure by Function (Fourteen Reporting Companies Only) ABIM Conference Product Monitoring / Stewardship 11.3% Research of New a.i. 32.5% Product Monitoring / Stewardship 12.2% Research of New a.i. 29.6% Development of Generics 1.8% Development of Generics 1.9% Post Launch Development 31.1% Development of New a.i. 23.3% Post Launch Development 31.4% Development of New a.i. 24.9% Total = $2,328million Total = $2,943 million Results of Study undertaken for ECPA and CropLife America 10

11 Company Sales and R&D Expenditure 2011 ABIM Conference Agrochemicals Seed and Traits Sales $m Monsanto DuPont Syngenta BASF Dow Bayer Agrochemicals Seed and Traits R&D Expenditure $m Monsanto DuPont Syngenta BASF Dow Bayer 11

12 R&D Expenditure of Leading Agrochemical Companies ABIM Conference 3500 Agrochemical R&D Seed and Trait R&D 3000 US$ million

13 Product Introductions and R&D by Crop ABIM Conference Number of new Active Ingredients Time period 1980/ / / /11 In R&D Herbicides Cereals Soybean Maize Rice F&V Other Total Insecticides F&V Rice Cotton Others Total Fungicides F&V Cereals Rice Others Total Others Total Average annual rate of introduction

14 14 New Active Ingredient Introductions No.of Products

15 Agrochemical Product Introductions and R&D Products Introduced Currently in R&D Bayer 35 6 Syngenta 15 4*** BASF 20 3* Dow 17 2 Sumitomo 15 1 DuPont 7 3* Monsanto 2 0 Other Japanese Rest 22 2 Total ** * Some in co-development with other companies ** some licensed products counted twice *** Syngenta has another 4 unidentified products in early development 15

16 a.i.s in development Agrochemical Active Ingredients in Development ABIM Conference

17 BASF Seed Companies: Input Traits - Development ABIM Conference Maize Soybean Cotton Canola Others Herbicide Tolerance* Nematode Resistance* Disease Resistance Bayer GlyTol Twinlink insect resistance Roundup Ready Insect Resistant Rice GlyTol + HPPD Herbicide Tolerance Dual Mode Herbicide Tolerance Liberty Link + Roundup Ready Fungus Resistant Rice Dow Enlist Corn Enlist Soybeans Enlist Cotton DuPont Monsanto Optimum AcreMax Xtreme Triple Mode Herbicide Tolerance Multiple Mode Herbicide Tolerance Novel Insect Resistance Roundup Ready 2 Optimum GLY Glyphosate Tolerance Herbicide Tolerant Rice Optimum Intrasect + DP4114 Aphid Resistance Liberty Link Insect Resistant Rice Lepidoptera Resistance III Coleoptera Resistance III Dicamba and Glufosinate Tolerance Genuity Rootworm Resistance III Genuity Corn borer Resistance III FOP Herbicide tolerance Goss's Wilt Resistance*** Gray Leaf Spot resistance Lepidoptera Resistance Hemiptera Resistance Asian Soybean Rust Resistance Genuity Intacta Genuity Bollgard III Roundup Ready 2 Dicamba Tolerance Dicamba and Glufosinate Tolerance Dicamba tolerance Insect protected Roundup Ready Sugarcane Herbicide tolerant wheat Roundup Ready 2 Xtend Lygus Control Roundup Ready + Liberty Link Gemini Virus Resistant Tomato*** 2nd Generation Cyst Nematode Resistance Asian Rust Resistance* 2nd Generation Phytophthora Root Rot Resistance Reniform Nematode Resistance Root Knot Nematode Resistance Phytophthora Resistant Peppers Syngenta Agrisure Viptera 3222 Insect Resistance Insect resistance (COT 102) Insect Resistant Rice Agrisure Duracade Disease Resistance *BASF / Monsanto partnership ** BASF / Embrapa partnership ***Developed through conventional breeding 17

18 Seed Companies: Output/Agronomic Trait Research ABIM Conference Maize Soybean Cotton Canola Others BASF Higher yielding* Higher yielding* Drought tolerance* Higher yielding* Higher yielding sugarcane Drought tolerance* Healthy fatty acids Higher yielding sugarbeet Improved Nitrogen Improved feed Amylopectin potatoes Higher yielding wheat* Stress tolerant wheat* Bayer Altered oil content Higher yielding Plant made pharmaceuticals Stress tolerance Hybrid rice Dow Healthy oils Stress tolerance Added Nutrition DuPont Seed production technology (yield) Higher yielding Higher yielding Hybrid rice Improved feed Plenish modified oils Improved processing Increased oils Improved Nitrogen Improved feed Drought tolerance Monsanto Higher yielding* Higher yielding* Drought tolerance* Higher yielding* Higher yielding wheat* Drought tolerance* SDA omega-3 oil Stress tolerant wheat* Improved Nitrogen Vistive Gold Syngenta Improved Nitrogen Carb Yield * In collaboration 18

19 Proprietary v Off Patent Market Share ABIM Conference Patented 23.0% Off - Patent 77.0% Proprietary 23.0% Proprietary Off Patent 25.3% Generic 51.7% Sales $m

20 Proprietary v Off Patent Market Share % Generic Proprietary Off-Patent Patented

21 Company Acquisitions Present Company Bayer BASF Monsanto Syngenta Dow DuPont Acquisition US seed company Hornbeck Seed, producer of soybean, rice and wheat Research company SoyTech Seeds Biological crop protection company AgraQuest US-based biological products company Becker Underwood U.S. based biotechnology company Divergence Bee health company Beeologics Precision Planting Public offer for the Belgian biotechnology company Devgen US-based biotechnology company Pasteuria Bioscience DuPont Professional Products insecticide business for $125 million GreenLeaf Genetics acquired the seed genetics licensing company JGL Inc Seed company Northwest Plant Breeding Company Brand and marketing assets of Prairie Brand Seed US-based alfalfa and clover company Cal/West Seeds Danish enzyme and food ingredient company Danisco South African Pannar Seed US seed company Dobler's hybrids 21

22 R&D Expenditure Historical development ABIM Conference Agrochemicals Seed and Traits Agrochemicals Seed and Traits R&D expenditure $m R&D Expenditure $m Monsanto DuPont Syngenta BASF Dow Bayer 0 Monsanto DuPont Syngenta BASF Dow Bayer 22

23 R&D Expenditure 2011 by Industry (Leading companies) R&D Expenditure ($m.) Agrochemical Seed and traits Biological crop protection 23

24 Disclaimers The information contained in this presentation constitutes our best judgement at the time of publication, but is subject to change. Phillips McDougall do not accept any liability for any loss, damage or any other accident arising from the use of the information in this presentation. The information given in this presentation has been drawn from analyses and reviews presented in the Phillips McDougall products AgriService, Seed Service, AMIS Global and AgreWorld. Phillips McDougall maintain a wide range of databases covering the crop protection and seed industries, this presentation presents only headline information. Access to these databases can be gained through subscription or consultancy. Our market research databases track product sales from global market totals down to brand level sales by crop and country in both volume, value and area treated terms. For more information about these products please visit

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