About Taipei Medical University. Jan. 2018

Transcription

1 About Taipei Medical University Jan. 2018

2 Outline 1. Current Status 2. Specific Strategies 3. Conclusion 2

3 TMU Organization 624 faculty members, 6,112 students Student-faculty ratio: 9.0 3

4 Vision & Goal & Strategy Strategy 1. Develop interdisciplinary education 2. Strengthen translational research & research focus 3. Innovate academia-industry collaboration 4. Emphasize globalization 5. Recruit & cultivate talent 6. Fulfill university social responsibility Goal To cultivate biomedical talents with humanity, innovative capability & global vision To establish a sustainable biomedical ecosystem Vision World class medical university 4

5 World U. Ranking QS Subject Ranking subjects in top Subjects in ESI* 2017 Ranking Subject World Ranking Taiwan Medicine Nursing 70 2 Pharmacy & Pharmacology QS World University Ranking No QS Asia No.76; THE Asia No.83 Subject Clinical Medicine Neuroscience & Behavior Social Sciences, General Pharmacology & Toxicology Biology & Biochemistry Agricultural Sciences * Source: QS Website: 2017 Rankings by Subject * Source: 2017 ESI Data * ESI: Selected from the most recent 10 years of data, Institutions reflect the top 1% of papers by field and publication year. 5

6 Top Notch Research Center Grant, MOE Cancer Translational Center Project (NT 130 million, Apr ~ Dec. 2017) PI: Prof. Yun Yen Co-PIs: Academy members- Leroy F. Liu, Wen-Chang Chang, Jacqueline Whang-Peng MPT0E028 has completed phase I clinical trial, the first one initiated by university in Taiwan, and will move on to phase II clinical trial in

7 Academia-Industry Collaboration (million) Research Fund from Industry Patent Granted (Case No.) Close File Grant Technology Transfer Fee Over NT 700 million dollars in the past 3 years (million) spin-off Companies Company Technology Capital BIOGATE PRECISION MEDICINE CORP. CALGENT BIOTECHNOLOGY CO., LTD. 394 Cancer vaccine New drug development 500 million 300 million 3D GLOBAL BIOTECH INC. 3D printing 1 billion 44 Stock Cash 7

8 Outline 1. Current Status 2. Specific Strategies 3. Conclusion (1) Develop interdisciplinary education (2) Strengthen translational research & research focus (3) Innovate academia-industry collaboration (4) Emphasize globalization (5) Recruit & cultivate talent (6) Fulfill university social responsibility 8

9 (1) -I Past Focus on Medical Now Equip Students with Capabilities Research Focus Academia- Industry Social Responsibility 9

10 (1) Medical Humanity -II Award Pilot University in General by MOE, 2010 (Only 2 universities got awarded) A continuous course of medical humanity education Ex: coordinated by the Department of Medical Humanity Create humanity environment in campus Establish Center for Humanity & Arts Provide seminar on humanity & arts Publish literature on medical humanity Research Focus Academia- Industry Social Responsibility 10

11 (2) Major Research Focus-I Clinical-oriented research Centered on translational medicine Develop interdisciplinary research team Taiwan Institutes Academic Sinica National Health Research Institute Industrial Technology Research Institute Development Center for Biotechnology International Institutes Case Western Reserve University Johns Hopkins University University of Southern California Stanford University University of Chicago NIH Research Focus Academia- Industry Social Responsibility 11

12 (2) Cancer Translational Research-II 3B Strategy Bench Bedside Business Ranking Cancers International Taiwan Breast Colorectal Prostate Brain 48 1 *Source: 2017 Web of Science Publications Drug Discovery & Molecular Diagnosis Precision Medicine IBM Watson for Oncology Joint Biobank Next-Generation Sequence Cancer Genomics Spin-off Companies BIOGATE PRECISION MEDICINE CORP. Cancer vaccine and antibodies through SpM platform Capital: NT 500 million CALGENT BIOTECHNOLOGY CO., LTD. Small molecule drugs for colorectal, bladder, pancreatic and TN breast cancer Capital: NT 300 million Research Focus Academia- Industry Social Responsibility 12

13 (2) Brain Medicine-III Ranking TBI Social Impact Subject Traumatic Brain Injury (TBI) Neurovascular Injury 2016 Ranking International Taiwan Mortality No , Law(1997) Lead to the legislation on Safety Helmet Law Save more than 3,000 lives every year (JAMA, 1995; 2011) Brain Image *Source: 2016 Web of Science Establishment of 2 Nationwide TBI Databases TBI Database is the world's biggest Database Site no. Case no. Starting year Unique Cohort: mtbi cohort for longitudinal studies 3,646 TBI Database Severe TBI Registry , , Patients no. Control no. Starting Year Research Focus Academia- Industry Social Responsibility 13

14 (2) Brain Medicine-III To study the insidious effects of concussion: novel translational approach for early detection and preventing cognitive decline Collaborated with NIH and supported by MOST and NIH ( ) Representative studies: Early biomarker for prognosis after mtbi Use fmri to detect the decrease of brain activation and working memory in mtbi patient Radiology, 2012; 2015; 2016 Prognosis by GABA A Receptor Use GABA A receptors PET image to detect the possibility of recovery from vegetative state Neuroprotection and therapeutic Strategies of mtbi Znf179 (Zinc finger 179) regulating Sp1 is a potential new drug target for neuro-protectant (Animal studies) mtbi Redox Biol, 2017; Neuropharmacology, 2016; Nucleic Acids Res, 2011 VS: Vegetative State MCS: Minimally Conscious State HC: Healthy controls Hum Brain Mapp, 2015 Research Focus Academia- Industry Social Responsibility 14

15 (2) Cell Therapy and Regenerative Medicine-IV Focusing on Unmet Medical Needs Translational Medicine Small Blood Cell Mesenchymal Stem Cell Systemic safety cell products Diabetes-related 1. Type I Diabetes 2. Diabetic retinopathy 3. Diabetic foot ulcer Diabetes (2015), Stem Cells (2016), Sci Rep. (2017), Stem Cell Reports (2017), TW patents Dental regeneration of aging people PLOS ONE (2014); US/TW patents MOST-Regenerative medicine program ( , NT 45 million) GTP Laboratory Joint Clinical Research Center Clinical Trials 2017-TFDA Approval MSC treatment in diabetic retinopathy (Phase I/II) 2017-TFDA under review SB cell treatment in dental implantation 2018-Application MSC treatment in severe burns (Phase I/II) 2019-Application SB cell treatment in diabetic foot ulcer (Phase I/II) Business Development TMU Biotech Commercialization (near future) GTP Lab. Clinical cell products TMU Team Spin-off Company JCRC Clinical trial Strategic partner (Cell storage) Research Focus Academia- Industry Social Responsibility 15

16 (2) Medical Device-V Translational Research Biomedical Materials Nanomedicine Biomed Engineering Spin-off GLOBAL BIOTECH Tech:3D Bio-printing for tissue engineering Capital:1 Billion APLUS SHINE BIOTECH Tech:Medical device for dental implant Capital:300 Million Biosensor Assistive Technology Dental Device Medicine Affiliated Hospitals V-CHECK BIOTECH Tech:Molecular diagnosis for endometriosis Capital:200 Million YDS BIOTECH Tech:Dental biomaterial for treatment Capital:10 Million MTAM BIOTECH Tech:Nano-medical fiber for drug screening Capital:10 Million Research Focus Academia- Industry Social Responsibility 16

17 (3) Entrepreneurship Ecosystem-I In accord with biotech industry policy in Taiwan Set up a comprehensive ecosystem integrating education, R&D, and industry Research Focus Academia-Industry Social Responsibility 17

18 (3) Venture Capital Fund & Biotech Park-II Complete the whole picture of TMU s ecosystem Holding Company First among Taiwan s universities To assist faculty to spin off their research results TMU Venture Capital Fund: provide financial support for start-ups TMU Biotech Park (in Shuang-Ho Campus) Completed by 2022 Building area: over 76,000 m 2 Translational platform: bridge university, hospitals and industry A primary hub of biotech industry in Taiwan Research Focus Academia-Industry Social Responsibility 18

19 (4) Emphasizing -I 8 English taught programs e.g.: Ph.D program for Translational Medicine Ph.D program for Cancer Biology and drug Discovery Master program in Global Health and Development All graduate programs admit foreign students 22 graduate dual degree programs e.g.: Case Western Reserve U. University of Southern California Dalhousie University Georgia State University Southern New Hampshire U. International student: 10.1% International graduate student: 15.4% (of total graduate student) Outbound students: 422 (7.2%) Inbound students: 349 (6.0%) Foreign Prof. as Dean and Vice Dean e.g.: Prof. Timothy Lane (USA) : Dean of College of Humanities and Social Sciences Prof. Thierry Burnouf (France) : Vice Dean of College of Biomedical Engineering Research Focus Academia- Industry Social Responsibility 19

20 (4) Strengthen Collaboration with Outstanding Universities-II University-level key partner One college, One key partner Examples of comprehensive collaboration: Case Western Reserve U. Establish joint research seed funds and teams 1. Student Exchange 2. Faculty Exchange 3. Dual Ph.D Program 4. Industry collaboration 5. Joint Research Seed Funds (Cancer, Neuroscience, Medical Device, Drug Development) Hokkaido U./ Kyushu U. Establish a regional academic alliance 1. Joint Symposium: TMU/ Kyushu/ Hokkaido 2. Student Exchange 3. Faculty Exchange 4. Research Collaboration Other Universities: Johns Hopkins U. U. of Southern California U. of Pennsylvania MOU with Hokkaido U. Research Focus Academia- Industry Social Responsibility 20

21 (5) Recruit outstanding scholars Recruit young scholars Attract foreign faculty & postdoctoral Sabbatical Establish friendly environment for foreign faculty By merit pay and chair professor system Academy members: NT 200,000/month MOE National Chair Professorship: NT 100,000/month Research team mentors Recruit 100 faculty members in 3 years Reduce student-faculty ratio from 9 to 7.5 Major research teams: Cancer, Brain, Respiratory, AI etc. Provide extra NT 20,000~NT 80,000/month incentive for foreign faculty compared to local faculty Set up Short-Term Visiting Scholar Subsidy Plan Offering salary, living expenses, airplane tickets, medical insurance, etc. Offering one-stop on-board services Creating language barrier-free environment Research Focus Academia- Industry Social Responsibility 21

22 (6) Social Responsibility-I Long-term Stationary Medical Mission teams Kingdom of Swaziland (since 2010) Marshall Islands (since 2013) Sao Tome and Principe ( ) Provide medical service and support public health prevention Emergency Air Medical Transportation System Since 2002, transferred more than 3,800 people through the system Improve medical condition of remote areas in Taiwan Medical Contribution Award 23 teachers and alumni won the National Medical Contribution Award Provide integrated care service from hospital to community Nursing Homes Dementia-Care sites Active Elderly-Service sites Research Focus Academia- Industry Social Responsibility 22

23 (6) International Contribution-II TMU and affiliated hospitals have been accredited by Corporate Social Responsibility (CSR) of The British Standards Institution (BSI) Research Focus Academia- Industry Social Responsibility 23

24 Outline 1. Current Status 2. Specific Strategies 3. Conclusion 24

25 Conclusion World Class University Translational Innovation Humanity Social Responsibility 25

26 Thank you for your attention