2014 Chemical Biology & Nitric Oxide Shanghai International Conference (NOSIC2014) PROGRAMME

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1 PROGRAMME 2014 Chemical Biology & Nitric Oxide Shanghai International Conference (NOSIC 2014) July 4-6, 2014, Shanghai July 4, 2014 ( Friday) Time Event Venue 9:00-22:00 Registration Hotel lobby, Academic Activity Center (1 st Floor), SJTU July 5, 2014 (Saturday), Morning Session: Opening Ceremony Venue: Main Conference Room, 1 st Floor, Chen Ruiqiu Building, SJTU Chair: Lee Jia(FZU), Ajun Wan(SJTU,TJU), Conference Executive Chairman Time Event Speaker 9:00-9:30 Welcome Speech Jin-pei Cheng, Vice Minister, Department of MOST Dan Wu, Vice President, SJTU Steven S.Gross, Co-Chair,WCMC of Cornell University

2 9:30-9:40 Group Photo Ran Huang (SJTU) Session: Keynote Speech Venue: Main Conference Room, 1 st Floor, Chen Ruiqiu Building, SJTU Chair: Jin-pei Cheng (MOST), Conference Chairman Time Event Speaker 9:40-10:10 10:10-10:40 Keynote Speech 1: Oxidation of Tetrahydrobiopterin, enos uncoupling and Endothelial Dysfunction in Chronic Cardiovascular Disease Keynote Speech 2: The foundation of molecular medicine: A chemical biology approach Steven S. Gross,WCMC of Cornell University,USA Weihong Tan,University of Florida, USA 10:40-11:00 Coffee Break Chair: Steven S.Gross (WCMC), Conference Co-Chair 11:00-11:30 Keynote Speech 3: One-Carbon Metabolism and the Prevention of Birth Defects in China Richard H. Finnell, University of Texas, USA 11:30-12:00 Keynote Speech 4: Structural basis and molecular mechanism of human soluble guanylate cyclase in NO-signaling transduction Xiangshi Tan,Fudan University

3 12:00-14:00 poster viewing /Lunch:Liu Yuan ( 留园 ) July 5, 2014 (Saturday), Afternoon-Evening Time Main Conference Room, 1 st Floor, Chen Ruiqiu Building, SJTU Session Chair: Xiangshi Tan,Fudan University 14:00-14:20 Mesoporous Silica based stimulus-responsive NO release system for inhibiting the growth of panc-1 solid tumor, Prof. Hangrong Chen, SIC of Chinese Academy of Sciences 14:20-14:40 Towards a Quantitative Endogenous Network Theory of Cancer Genesis and Progression:beyond cancer as diseases of genome Prof. Ping Ao,Shanghai Jiaotong University 14:40-15:00 15:00-15:20 Towards Building an Ideal Proteomics Platform Prof. Chen Ding, Beijing Proteome Research Center Development of small molecule fluorescent probes for nitrosative and 1-e- oxidative chemistry of nitric oxide Prof. Youjun Yang,East China University of Science and Technology of China 15:20-15:40 Coffee Break

4 Session Chair: Hangrong Chen (SIC, Chinese Academy of Sciences) 15:40-16:00 16:00-16:20 16:20-16:40 16:40-17:00 Quantum Dot Based Fluorescence Turn-on Nanoprobe for Selective and Sensitive Nitric Oxide Detection Prof. Suhua Wang, Institute of Intelligent Machines, Chinese Academy of Sciences An Electrochemical System to Detect Intracellular Purine based on Enzyme Catalysis Prof. Dongmei Wu, Jiamusi University A Non-Peptide-Based Fluorogenic Small-Molecule Probe for Elastase Prof. Guang-Fu Yang, Central China Normal University Mechanisms of V-PYRRO/NO Regulating MRNA Expressions of LTC4 Synthase During Hepatic Ischemia Reperfusion Injury in Rats Prof.Yang Shu-long, Nanchang University, 17:00-18:30 Reception / Liu Yuan ( 留园 ) 19:00-21:00 BB Session: Roundtable meeting (By invitation only) Chair: Lee Jia, Ajun Wan Venue: Small Conference Room ( 学术厅 ) (2nd Floor, Academic Activity Center, SJTU) 1. Proposals for 973 project, arrangements and applications. 2. Proposals for NSFC key projects. 3. Discussion the establishment of the Alliance for NOSIC.

5 July 6, 2014 (Sunday), Morning Session: Keynote Speech Venue: Main Conference Room, 1 st Floor, Chen Ruiqiu Building, SJTU Chair: Richard H. Finnell, University of Texas, USA Time Event Speaker 9:00-9:30 9:30-10:00 Keynote Speech 1: From endothelium-derived relaxing factor (EDRF) to intervention of adhesioninvasion of circulating tumor cells to endothelium: a new horizon in biomedical nitric oxide research Keynote Speech 2: Design and Testing Novel Nitric Oxide Donor Compounds 10:00-10:20 Coffee Break Chair: Lee Jia (FZU), Conference Executive Chair Lee Jia,Fuzhou University Peng George Wang, Georgia State University,USA 10:20-10:50 10:50-11:20 Keynote Speech 3: Metabolomics for Discovering the Functions of Essential Genes Keynote Speech 4: Computational and Bioinformatics Investigations of NO-related Protein Post-translational Modifications Steven S.Gross, Cornell University,USA Yi-Lei Zhao, Shanghai Jiao Tong University

6 11:20-11:50 Keynote Speech 5: Targeted Intracellular Delivery of Nitric Oxide Using Fluorescence Trackable Functional Nanoplatform Jin-Gang Liu, East China University of Science & Technology 11:30-14:00 Poster Viewing /Lunch:Liu Yuan ( 留园 ) July 6, 2014 (Sunday), Afternoon Time Main Conference Room, 1 st Floor, Chen Ruiqiu Building, SJTU Session Chair: Jin-Gang Liu, East China University of Science & Technology 14:00-14:20 14:20-14:40 Construction and function evaluation of SePEI/Hep-PCL vascular graft for in situ catalytic nitric oxide generation Prof. Shufang Wang, Nankai University Studies on Synthesis and Biological Evaluations of Nitric Oxide Donating Drugs Prof. Zhangjian Huang,China Pharmaceutical University

7 14:40-15:00 Naphthalimide-based Fluorescent chemosensors for Hg2+ Prof.Yong Ye, Zhengzhou University 15:00-15:20 Selective Fluorescent Probe for Nitric Oxide Imaging in Living Cells Prof. Xiang Chen,Sun Yat-Sen University 15:20-15:40 Coffee Break 15:40-16:00 16:00-16:20 16:20-16:40 16:40-17:00 17:00- Optimization of Preparation of Cinnamaldehyde Microencapsulation by Response Surface Methodology Prof. Liu Huan, Tonghua Normal University Novel nitric oxide-releasing derivatives of farnesylthiosalicylic acid: synthesis and evaluation of anti-hepatocellular carcinoma activity Prof. Yong Ling, China Pharmaceutical University An Association of Reaction Time with bone Quantitative Ultrasound Prof. Jun Feng Mao, Naval Command College Application of Ethyl Cellulose as Nitric Oxide Releasing Carrie Prof.Yixiang Shi, Shanghai Jiaotong University Closing and Award Ceremony Closing Remark: Lee Jia Announcing the award winners: Ajun Wan