Strengths of Instrumentation Division, IIIM, Jammu

Transcription

1 Strengths of Instrumentation Division, IIIM, Jammu Quality & Reliability Skill / Technologies Complete analytical services available in-house Availability of large number of qualified experts Strict adherence to guidelines Analytical instruments availability Highly qualified and experienced staff One stop solution Cost Providing integrated offers for analytical services as well as hands on training for industry people Significant cost saving through full integration

2 Instrumentation Facilities Available 1. NMR Spectrometers Bruker 400MHz & Bruker 500MHz Services and Application in 1H, 13C, 15N, 31P and all other nuclei D2O Exchange 2-D COSY, HMBC, HMQC including 1D experiments required NOESY, ROESY, TOXCY etc. Industry GLP and GCP bioanalytical studies Structural Characterization Identification of Impurities and Unknowns DEPT 45, DEPT 90 & DEPT 135 (Combined) stability studies of Proteins and Biologics

3 2. LC-MS/MS LC-Q-ToF Waters Synapt Services and Application Direct Injection Mass Drug Metabolism Studies Direct Injection Mass/MS-MS (n-1) Direct Injection Mass/MS-MS (n-2-9) In Vitro Drug Metabolism High-Throughput LC-MS Analysis of Drugs Quantification analysis Analysis and Identification of Impurities and Degradation Products in Pharmaceuticals Analysis of Chiral Impurities in Pharmaceuticals

4 3. HIGH RESOLUTION LCMS/MS Agilent UHD 6540 LC-Q-TOF Direct Injection Mass Services and Application Drug Metabolism Studies LCMS & LCMS/MS CHN Determination Protein Sequencing Chemical Formula Generation Analysis of Chiral Impurities in Pharmaceuticals High-Throughput LC-MS Analysis of Drugs Analysis and Identification of Impurities and Degradation Products in Pharmaceuticals In Vitro Drug Metabolism

5 5. GC-MS/MS Varian 4000 and Agilent 7890A with HSS Services and Application GCMS in EI mode Qualitative and Quantitative analysis of Volatile molecules Direct Injection Mass in EI mode Analysis of sample with library

6 6. HPLC /Prep Agilent 1100 series with autosampler, PDA detector & column oven Shimadzu UFLC with autosampler, PDA detector & column oven Services and Application Using C-18,C-8 or Phenyl Columns and UV/ PDA detectors Qualitative Analysis for Purity/Impurity Profiling Isolation of API/secondary Metabolite from synthetic and Natural sources Quantitative analysis Method Validation Quantitative analysis Degradation studies

7 8. FTIR Perkin Elmer Spectrum II Services and Application Identification Of API Normal Spectrum Qualitative Stability testing Characterization of molecules

8 9. UV spectrophotometer Shimadzu UV 2600 Services and Application Normal Spectrum Qualitative Normal Spectrum Quantitative Purity testing identification of API

9 10. POLARIMETER Perkin Elmer M240 Services and Application Specific Optical Rotation for each wave length Purity profiling

10 11. Elemental Analyzer Elementar Cube Services and Application C, H, N & S identification in sample Purity profiling

11 12. FREEZE DRYER (Lyophilizer) Telstar Lyobeta Services and Application Drying of herbal products and biological products Drying of dosage forms and API

12 13. Liquid Nitrogen Plant StirLin1 and Wirac Services and Application Cryopreservation Cryo experiments