Regenovo 3D Bioprinter. Beyond imagination Print future

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1 Regenovo 3D Bioprinter Beyond imagination Print future

2 Features: The introduction of : Regenovo Biotechnology Co.,Ltd. is a high-tech enterprises that provide professional integrated solutions in 3D printing technology for biomedical applications. REGENOVO devoted to develop biomedical 3D printer equipment, materials and software for regenerative medicine, tissue engineering, drug discovery and personalized medical applications. REGENOVO tries to open doors to new diagnostic, prevention and treatment techniques. Services of Regenovo including: v To provide new research tools for the life sciences and materials sciences researchers; v To provide new technology for the artificial organs or tissue repair scaffolds for the patients with organ defects; v To print drug screening models and new controlled release drug stents for pharmaceutical companies; v To print personalized medical devices.

3 Regenovo Biotechnology Co.Ltd.and Hangzhou Dianzi University have jointly created bioprinter--regenovo 3D Bioprinter. According to the freely designed or medical imaging data-reconstructed 3D models, the Regenovo 3D bioprinter can build complex 3D structures by biomaterials embedded with living cells. This new printer is in a leading position in the world as it is various materials available, highly accurate, low cell damage rate, and has high ntegration degree. Applications: To provide new research tools for the life sciences and materials sciences researchers; To print the artificial organs or tissue repair scaffolds for the patients with organ defects; To print drug screening models and new controlled release drug stents for pharmaceutical companies; To print personalized medical assistive devices.

4 Technical parameters: PppPrPparameter Three-axisautomatic positioningsystem s Control precision(xyz): 0.02/300mm 0 Forming speed: max 170 mm/s Size of printed structure: mm The high temperature nozzle: 50~260oC The low temperature nozzle: -5~65oC The temperature of printing platform: -5~65oC Equipment size and weight: cm, 50 kg Supported data types: STL, GCODE Operating System: Windows System Power voltage: 110~240 V AC

5 Features: Solid State temperature control Systems: Using an independent solid state refrigeration unit, the liquid medium and the pipeline network, the heat transfer and temperature in the print platform and nozzle can be precisely controlled, Two nozzles printing system: Supporting the printing of living cells and the biomaterials melted between -5 to 260 (The high temperature nozzle 50~260 and the low temperature nozzle -5~65 ). The SLS-fabriacted nozzles used the optimized design of heat exchange efficiency. The overall structure of 3D printing system and materials are aseptic. This ensures the the prototyping chamber of Regenovo 3D bioprinter is clean and is suitable for assembling the biomateials and cells under sterile condition.

6 Bioprinting Materials: D Bioprinter can operate materials which are used in biomedical fields including regenerative medicine, tissue engineering, drug development and medical assistive devices, to produce roducts with well-designed shape and internal structure. The materials may be used include medical polymers, inorganic materials, hydrogel materials and live cells. v Repair and regeneration materials of bone tissue: Hydroxyapatite, Tricalcium phosphate, Nacre, polyetherketoneketone. v Soft-tissue scaffolds: Gelatine, Alginate, Fibrin, Collagen, Agar, Chitosan. v Living cells: embryonic stem cell, adipose-derived stem cells, bone marrow derived mesenchymal stem cells, Liver cells, Tumor Cell. v Controlled release drug stents: PLLA, PLGA, PCL, Sodium Starch Glycolate. v Medical assistive devices: Silicone, Polyurethane.

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