Includes 'study abroad' Description This lecture module will introduce the following topics: Assessment Assessment Type Exam 1 (100%) Convenor

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1 Biomedical Sciences This edition of the University of Nottingham Catalogue of Modules went to press on 7th September It was derived from information held on the database. The Catalogue is also published on the Web at Circumstances may arise which cause a module to be modified or withdrawn and the database will be updated to reflect this. Thus, if you find a discrepancy between the information printed here and that published on the Web, you should regard the latter as definitive.

2 Autumn Semester Level 1 B11101 Fundamentals of Human Physiology and Pharmacology 1 Credits 20 Level 1 Target students Students registered for course B141, B140, B1B2 and B1C7. Also availabe to any other students wishing to take as an optional module. There is a limit to the number of places on this module. Students are reminded that enrolments which are not agreed by the Offering School in advance may be cancelled without notice. Description This module will provide a basic understanding of the physiology and pharmacology of excitable cells and the nervous, cardiovascular, respiratory and urinary systems in man, including aspects of drug action. 3 lectures/week, 2 revision seminars, 4 practicals and associated background reading. Students will be required to produce a short report on 2 of the practicals and to attend the revision seminars at which they should be able to discuss and answer questions on topics covered in the lectures. A CAL MCQ quiz and a student-directed learning package are available on WebCT. Type Exam 1 (80%) Coursework 1 (20%) Dr V Ralevic 2 short answer essay questions plus online MCQ exam - please note that this module is not available to exchange students who will NOT be present in Nottingham at the time of the assessment. Laboratory reports B11102 Introductory Human Physiology and Pharmacology 1 Target students Life Science, Psychology, Genetics, Human, Genetics, Biology, Zoology, Biochemistry and for Biomedical Materials (Compulsory) Description This module will introduce the physiology and pharmacology of the central nervous, cardiovascular, respiratory and urinary systems in man, including aspects of drug action. Three lectures per week and associated background reading. A CAL MCQ quiz is available on WebCT Type Exam 1 (100%) Online multiple-choice examination - please note that this module is not available to exchange students who will NOT be present in Nottingham at the time of the assessment. Dr V Ralevic Target students Biochemistry, BBC (3 and 4 year), BG, genetics, human genetics, neuroscience (3 and 4 year), biomedical material science, chemistry, Description This lecture module will introduce the following topics: structure and function of cells and cell organelles protein and enzyme structure and function the processes of energy transduction from macromolecules biosynthesis of cell components the role of cell membranes in barrier and transport processes. 3 per wk. 1hr0min Three lectures per week - Thursday at 10am and 11am, Friday at 10am. These days and times are to fit in with the Medical School timetable. Type Exam 1 (100%) Dr S Brown one on-line multiple choice examination C71102 Cell Structure and Metabolism (P) Target students Biochemistry and Genetics, Human Genetics, Genetics and Biochemistry & Biological Chemistry, Neuroscience (3 and 4 year) degree students Description This practical module will provide students with experience of the following topics: accurate assay of biochemical molecules separation techniques function of mitochondria in biological oxidation properties of proteins and enzymes enzyme purification solution of biochemical problems. Practical One 3-hour practical per week. This module is for Biochemistry and Biological Chemistry or Biochemistry and Genetics or Genetics or Human Genetics students and is run on Friday afternoons. Please note: failure due to non attendance (missing more than 2 sessions) will result in a student having to retake the module with residence. Type Coursework 1 (100%) Dr S Brown Practical reports and test.

3 C71104 Introductory Practical Biochemistry Target students Biochemistry students C700 Description This practical module will provide students with experience of the following topics: handling and recognising cells and organelles accurate assay of biochemical molecules separation techniques function of mitochondria in biological oxidation properties of proteins and enzymes enzyme purification solution of biochemical problems. Practical One 3-hour practical per week. It is run on Thursday afternoons for Biochemistry and Neuroscience degree students. Please note: failure due to non-attendance (missing more than 2 sessions) will result in a student having to repeat the module with residence. Type Coursework 1 (100%) Dr S Brown Practical reports and test. Level 1 Spring Semester C71205 Fundamentals of Biochemistry Target students Studnts registered for Biochemistry degrees or science degrees with appropriate pre- and co-requisites Semester Spring Prerequisite Introductory cell biology (C11113) or equivalent biological background is sufficient C41202 Genes and Cellular Control I (L) Description The course will review the structural and chemical principles underlying the functions of proteins and nucleic acids. The treatment will consolidate the learning and understanding students have achieved from (or C11113), and C41202 modules, and provide a sound basis for development of important themes in later years of the biochemistry degrees. Topics will be considered within a framework of adaptation of protein structure to function, how this is modified in human disease and simple analytical tools that can be applied to the study of disease. Chemical/physical properties of amino acid side chains Peptide bonds. Protein structures 1', 2', 3' and 4' and post-translation modifications. 3D structures of proteins. Conserved folds, domains and interactions. Protein analysis. Specific protein structures; eg. Antibodies. Protein engineering Structures, Physical and Chemical properties of Nucleotides & Nucleic Acids Basic principles of DNA replication, transcription/translation/genetic code. Basic principles of positive/negative gene regulation at the level of the promoter. Organisation of Genes and Genomes. Basics of DNA cloning 2 per wk. 1hr0min Type Exam 1 (100%) Dr P Jones 2 essays

4 Level 1 Full Year B11103 Fundamentals of Neuroscience Credits 20 Level 1 Target students MSci Neuroscience; BSc Neuroscience; BSc Neuroscience with Biochemistry; BSc Neuroscience with Pharmacology There is a limit to the number of places on this module. Students are reminded that enrolments which are not agreed by the Offering School in advance may be cancelled without notice. B11101 ndamentals of Human Physiology and Pharmacology 1 B11102 Introductory Human Physiology and Pharmacology 1 C11211 ndamentals of Human Physiology and Pharmacology 2 C41202 C41203 C71102 Genes and Cellular Control I (L) Genes and Cellular Control I (P) Cell Structure and Metabolism (P) Description Students will receive lectures on the gross structure of the brain and peripheral nervous system; major cell types of the nervous system and control of blood flow to the brain. In addition there will be an introduction to neurotransmission and diseases of the brain including multiple sclerosis. In the final part of the module students will receive a variety of lectures from different staff which will introduce topics that will be expanded upon in later years of the neuroscience courses. There will be a small element of computer-based practical work related to the investigation of brain function and how it can be monitored. There will also be a series of seminars on aspects of neuroscience reflecting current interests of members of academic staff in Nottingham. Subjects will include current research and technological advances in various areas of neurobiology or neurological and mental disease. Students will gain a broad knowledge of the application of neuroscience in industry and medicine. A series of seminars, lectures, computer based workshops, visits, student-centred learning and student presentations. Type Exam 1 (50%) Coursework 1 (17%) Oral (15%) Laboratory (18%) Dr A Brown Online exam Essay(1500 words) 10 min oral presentation Lab Report B11105 Introduction to Neuroscience Target students Students with an interest in Neuroscience Description Students will receive lectures on the gross structure of the brain and peripheral nervous system; major cell types of the nervous system and control of blood flow to the brain. In addition there will be an introduction to neurotransmission and neurodegenerative diseases, diseases of the brain including multiple sclerosis. In the final part of the module students will receive a variety of lectures from different staff which will introduce many of the different applications of neuroscience: disease (eg alzheimer's, schizophrenia etc), pain, behaviour, sleep etc. There will be a small element of computer-based practical work related to the investigation of brain function and how it can be monitored. A series of seminars, lectures and computer based workshops. See module timetable for more detailed information. Type Exam 1 (100%) Dr A Brown Online exam B11TUT Neuroscience Year 1 Tutorials Credits 0 Level 1 Target students First Year students on: B141 Neuroscience B140 Neuroscience B1B2 Neuroscience with Pharmacology B1C7 Neuroscience with Biochemistry There is a limit to the number of places on this module. Students are reminded that enrolments which are not agreed by the Offering School in advance may be cancelled without notice. Description Neuroscience Year 1 tutorial sessions and ad hoc bookings (module evaluation sessions, placement information meetings etc). This module does not contribute to assessment of the course but is included as a compulsory module for timetable purposes. Type (%) Professor KCF Fone

5 C71103 Biochemical Skills Credits 20 Level 1 Target students Students registered for C700 Biochemistry only C41202 C41203 C71102 Genes and Cellular Control I (L) Genes and Cellular Control I (P) Cell Structure and Metabolism (P) Description This module is designed to aid students in acquiring key communication and interpretative skills that underpin the practice of biochemistry. These will cover scientific reasoning, experimental design, paper criticism, statistics and mathematical processing of biochemical data. The module is delivered in small group tutorial and problem classes in which experience of essay writing, data handling and the preparation of oral and poster presentations will be gained. Tutorial 1 per wk. 1hr0min 1 per wk. 1hr0min The lecture and tutorial sessions will be delivered by personal tutors. Two sessions per semester will be used for a personal and academic tutorial. In addition, students will attend six three hour sessions for oral and poster presenations. Type Coursework 1 (50%) Coursework 2 (50%) Dr J Arnold two 1500 word essays and a problem class one oral and one poster presentation Index by B11101 B11102 B11103 B11105 B11TUT C71102 C71103 C71104 C71205

6 Index by title Biochemical Skills Cell Structure and Metabolism (P) Fundamentals of Biochemistry Fundamentals of Human Physiology and Fundamentals of Neuroscience Introduction to Neuroscience Introductory Practical Biochemistry Introductory Human Physiology and Phar Neuroscience Year 1 Tutorials