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1 Biology Tuesday, September 8 Wednesday, September 9, 2015 Do-Now: LS1 Vocab 1. Begin your LS1 vocabulary Recall: you may use the vocabulary builder WS (in the cabinet) or you may use flashcards Flashcards must include the word, definition, and a picture Reminder: vocabulary, once stamped off, may be used on any quiz or test 2. Have your table of contents and planner out Announcements& Iceland(Registra/on(( Register(by(9/17( Table(of(Contents(due(by(Fri(9/18( See(me(for(stamps(before(school,(at( nutri/on,(or(at(lunch( Progress(Reports(due(9/21( Make(up(assignments/quizzes(by(9/14( Planner: Finish LS1 Vocabulary by Mon 9/14 DNA/Central Dogma A Quiz Mon 9/14 Table of Contents #1 17. LS1 Vocabulary Power Notes Study Guide 1&

2 9/12/15& Standard HS-LS 1-1: Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells. FLT I will be able to diagram and describe the structure of DNA by completing 8.2 Power Notes Power Notes 8.2 Noise level 0 Copy down all bolded ideas Raise your hand to question/comment Be prepared to pair-share 8.2: Structure of DNA Key Concept: DNA structure is the same in all organisms 2&

3 What is DNA? Recall! DNA = deoxyribonucleic acid! Contains our genetic information!! It is a double-stranded nucleic acid! It is found in the nucleus! Contains the code for creating proteins What is DNA? Overall shape:! Double helix! DNA is a nucleic acid! Add next to box:! DNA is made up of nucleotides What is a nucleotide??? Write/draw on the bottom:! Nucleotides have 3 parts:! 1. Phosphate! 2. Deoxyribose sugar! 3. Nitrogenous base (4 different types) Backbone Bases 3&

4 DNA Backbone (fill in boxes):! 1.Deoxyribose sugars! 2.Phosphates Nucleotides Since there are four types of nitrogenous bases, there are four types of nucleotides One for each type of nitrogenous base Pyrimidines = Single Ring Thymine Cytosine Purines = Two Rings Adenine Guanine 4&

5 9/12/15& Base-pairing rules:! A bonds with T! G bonds with C 5&

6 9/12/15& Complementary Strands If one of the strands of DNA is C-G-A-A-T! The strand next to it would have to be G-C-T-T-A! What about for T-T-G-C-G?! It must be A-A-C-G-C! We call these complementary strands because they match. Bonding 1. The sugar-phosphate backbone = covalent bonding (strong)! 2. The nitrogenous bases = hydrogen bonding (weaker) hydrogen bond covalent bond 6&

7 Structure Structure Watson and Crick helped determine the 3D structure of DNA by building models They realized that DNA is a double helix that is made up of a sugar-phosphate backbone on the outside with bases on the inside Scientists Watson and Crick s discovery built on the work of Rosalind Franklin and Erwin Chargaff! Chargaff s rules:! A = T, and G = C (equal amounts)! 7&

8 Pair-Share-Respond 1. DNA is a nucleic acid. This means it is made up of. 2. A nucleotide has 3 parts what are they? 3. Which of those 3 parts make up the backbone of DNA? 4. What strand would be complementary to A-A-T-G-T-A-C? 5. What kind of bonds hold the backbone together? CW Study Guide 2. Finish vocabulary 3. Catch up on stamps 4. Quiz on DNA Monday Biology Tuesday, September 8 Wednesday, September 9, 2015 Do-Now: Brainstorm Week 4 Title your paper Brainstorm Week 4 1. Write down today s FLT 2. What DNA strand would pair up with the strand T-G-A-C? 3. Draw a picture of DNA, and label the following:! Hydrogen bonds! Sugar-phosphate backbone! Nitrogenous bases 8&

9 Planner: See Ms. Fleming for stamps + re-takes Study for quiz Table of Contents #1 20. Brainstorm Week Central Dogma Notes A 22. Central Dogma WS A Brainstorm Protocol Goal: generate the longest list possible Quantity > Quality Take turns clockwise ONE answer per person, and NO skipping You can help your classmate think of an answer, but you cannot tell them an answer Everyone must have the SAME EXACT list Pencils/Pens MUST be down when time is up Brainstorm Protocol Identify the person in your group with the most siblings This person will be starting Number your paper underneath your donow Brainstorm Protocol You will have one minute and thirty seconds to generate answers Group with the longest list = +5 dojo points each Your topic is. 9&

10 Brainstorm Protocol Tell me everything you know about DNA (structure, purpose, location, scientists, rules, etc) Brainstorm Protocol Count up your answers. 0:59 0:58 0:57 0:56 0:55 0:54 0:53 0:52 0:51 0:50 0:49 0:48 0:47 0:46 0:45 0:44 0:43 0:42 0:41 0:40 0:39 0:38 0:37 0:36 0:35 0:34 0:33 0:32 0:31 0:30 0:29 0:28 0:27 0:26 0:25 0:24 0:23 0:22 0:21 0:20 0:19 0:18 0:17 0:16 0:15 0:14 0:13 0:12 0:11 0:10 0:09 0:08 0:07 0:06 0:05 0:04 0:03 0:02 0:01 1:29 1:28 1:27 1:26 1:25 1:24 1:23 1:22 1:21 1:20 1:19 1:18 1:17 1:16 1:15 1:14 1:13 1:12 1:11 1:10 1:09 1:08 1:07 1:06 1:05 1:04 1:03 1:02 1:01 1:00 End 1:30 Standard HS-LS 1-1: Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells. FLT I will be able to compare and contrast DNA and RNA by completing Central Dogma Notes A Notes Protocol Noise level 0 Copy down all bolded ideas Raise your hand to question/comment Be prepared to pair-share 10&

11 of molecular biology 9/12/15& Recall DNA contains the information needed to create proteins Proteins control our cellular processes DNA must remain protected inside the nucleus So how do we make proteins outside of the nucleus??? Central Dogma DNA RNA PROTEIN Transcription Translation Central Dogma Central Dogma of Molecular Biology: Central Main Belief Dogma of molecular biology Main or important Belief or principle Nucleus Nucleus Ribosome 11&

12 of molecular biology 9/12/15& Central Dogma part 1 DNA RNA PROTEIN Transcription Part 1: Transcription RNA = Ribonucleic Acid DNA cannot leave the nucleus One of the DNA strands is copied into a form called RNA This RNA strand, called messenger RNA (mrna), can carry DNA s code out of the nucleus Central Dogma DNA vs. RNA 12&

13 DNA vs. RNA DNA: RNA: Double stranded Single stranded Deoxyribose sugar Ribose sugar Bases A, C, T, G (A=T, Bases A, C, U G (A=U, G=C) G=C) Stays in the nucleus Can leave the nucleus Part 1: Transcription Transcription = process where an mrna copy of DNA is made This occurs in the nucleus The mrna strand is complementary to the DNA strand Base-pairing: A-U and G-C Part 1: Transcription To make mrna, use base-pairing rules G pairs with C, and A pairs with U Practice If a DNA strand is A-T-T-G-C-T-C-C! The complementary DNA would be T-A-A-C-G-A-G-G! The complementary mrna will be U-A-A-C-G-A-G-G! What will the complementary mrna strand be for C-C-A-G-T-T-A-A-C?! Answer:! G-G-U-C-A-A-U-U-G 13&

14 CW 1. Central Dogma WS A 2. Binder assignments!!!!!!!!!! 3. Study quietly 14&