SPO GRANTS (2001) PHASES

Transcription

1 2002

2 SPO GRANTS (2001) PHASES MAIN PHASES Legal organisation of the Institute of Biotechnology Ankara University Biotechnology Labs Organisation of Central Lab of the Institute of Biotechnology/ Purchase of the equipments The launch of graduate studies at the Institute of Biotechnology 1st year 1st & 2nd year 1st & 2nd year 1st & 2nd year The Partnership of AÜ-SME Technology Development Centre From 1st to 6th year The Partnership of AÜ-SME Industry From 2nd & 6th year The Establishment of AÜ Biotechnology Park 3rd year Socio-economic Development Studies 1st year

3 Prof.Dr.Şevket Aziz Kansu Building (5th Floor)

4 MANAGEMENT Director Vice Directors Executive Board Grant Evaluation Group (GEG) Central Laboratory Instrumental Analysis Unit

5 EDUCATION 72 academicians from different faculties of our university have participated to our education program. Graduate programs: * MSc in Basic Biotechnology * MSc in Socio-economic development and biotechnology * MSc in Bioinformatics * PhD in Biotechnology * PhD in Socio-economic development and biotechnology

6 Grants *From different faculties of our university *195 grant proposals have been received. 140 grant proposals have been approved by the GEG and the Executive Board. 53 grant proposals have been rejected (26%). Two projects were suspended. *54 projects were accomplished. 30 of our projects are conducted in collaboration with national/international universities and several state organisations. *55 international scientific paper were published out of these projects.

7 INSTRUMENTAL ANALYSIS UNIT

8 CENTRAL LABORATORY FUNCTIONAL GENOMICS UNITS 09 Dec., 2004

9 In the 1300 m2 Functional Genomics Laboratories

10 From cells to organisms

11 FROM GENES

12 TO GENOMES

13 And PROTEOMES

14 In The Functional Genomics Laboratories Compilation of the inventory of the genetic resources of our country many studies are conducted from cells to organisms, from genes to genome and proteome,

15 In The Functional Genomics Laboratories Identification of new genes that have been linked to different diseases, Characterisation of new proteins that can be drug targets,

16 In The Functional Genomics Laboratories Obtain products from biological sources (microorganisms, plant, animal, human, cell lines); Production of biotechnological solutions for environmental pollution; Development of materials and/or applications for/related to functional biology (genomics, proteomics, metabolomics), drug discovery, tissue engineering, artificial organs and biomaterials;

17 In The Functional Genomics Laboratories Development of transgenic plant and animal models; Conduct risk analysis of genetically modified organisms; Molecular identification and typing of microorganisms, plants, animals and human.

18 THE CENTRAL LABORATORY Genomics Unit Application of FDG-PET and Molecular Gene Profiling for Risk Stratification of Diffuse Large B-cell Non-Hodgkin s Lymphoma in Different Ethnic Populations. The investigation of the effects of H2AX gene SNPs on the phenotype of patient with AT. The determination of the structural protein dynamics during human stem cell proliferation and differentiation stages.

19 THE CENTRAL LABORATORY Proteomics Unit The determination of the Amyloid protein with two dimensional liquid chromatography. The improvement of Bioprocesses of industrial enzymes by proteomic techniques. The improvement of DNA vaccines and fast diagnostic PCR kits for Campylobacter infections. The investigation of manufacturing conditions of active and stable Lipase enzyme of Bacillus sp. isolated from factory waste materials and its uses in detergant industry. Investigation of Proteomic biomarkers of alcohol use disorders. The Proteomic Research on rat bone marrow mesenchymal stem cells. The molecular epidemiology and prophylactic approach on bluetongue virus in Turkey: The effects of different inactivation methods on capsitis proteins. The evaluation of bioprocesses of erythropoietin production 6D5 Monoclonal Antibody: A New Promising Marker for Hepotocellular Carcinoma

20 THE CENTRAL LABORATORY Plant Biotechnology Unit 1. A Pilot Project for New SSR DNA marker Development in Career Advancement Studies: SSR locus isolation by Microsatellite-AFLP from some crop and endemic plant species in TURKEY and its use in the characterization of genetic resources. 2. Cloning of some grape genes in ABA pathway. 3. Comparing of root gene expression profilling between V.vinifera and Grape rootstocks by Affymetrix Gene Chip. 4. Transcript profiling of wild barley exposed water-deficit and isoosmotic salinity. 5. Identification and analysis of 7000 Expressed Sequence Tags(EST) from abiotically stressed grape root. 6. Identification of Higly Economic Important Fruits Species and Grape Germplasm by High-throughput Molecular Methods.

21 RESULTS & PRODUCTS A new form of syndromic deafness and the related gene has been identified. (Tekin M et al, AJHG, 80, 2, 2007) Taq DNA Polimerase production. Oligonucleotide production New treatment models Stem cell therapy for heart muscle. Cartilagetissueproduction.

22 Scientific Meeting Organisation

23 6th Ankara Biotech Days

24 WORKSHOPS Biosensors April 2006 Plant Biotechnology 4-5 May 2006 C.elegans genetics and RNA interference 5-6 April 2007 (more than 400 participants)

25