International Symposium Life at the Interface

Transcription

1 International Symposium Life at the Interface Centenary of the Institute of Pathology in Mainz ( ) & Retrospective of the Chair of Pathology ( ) [Univ.-Prof. C. James Kirkpatrick, MD, PhD, DSc, FRCPath] May, 2015 Main Lecture Hall in the Clinic of Surgery (Building 505) University Medical Centre of the Johannes Gutenberg-University Mainz 1

2 Andreas Felger, Hic gaudet mors succurrere vitae, ( here death is pleased to serve life ) Wooden relief in the entrance hall of the Institute of Pathology (since 1989) Learn from yesterday, live for today, hope for tomorrow. The important thing is not to stop questioning. (Albert Einstein) Ladies and Gentlemen, Dear Colleagues, We are delighted to celebrate with you 100 years of Pathology in Mainz. This period is characterized by many changes, not just at the level of the institute s buildings, but of course at the level of personalities as well as the specialities in the diagnostic service, not to mention the areas of research. However, two aims were absolutely stable during that long time to offer the best diagnostic service for patient care and to initiate innovative research. Examples of the latter are connective tissue pathology, paediatric pathology and renal pathology, which are all closely related with pathologists from the institute in Mainz. The approach taken to succeed in research activity also followed a strategic direction during that time, namely that to learn best from pathological conditions, modern methods should be available. Thus, over the years the institute in Mainz accommodated three generations of electron microscopes, established early automated immunohistology, a comprehensive molecular pathology unit and recently a fully automated robotic-based tissue bio-bank. Over the past two decades the REPAIR-lab was established as an experimental facility to study biomaterial-based regeneration, including nanomedicine. In the early days of pathology in Mainz learning from disease was greatly assisted by high autopsy activity. With time, the aim and practice of pathology has changed dramatically. Nowadays, pathological services are essential to help optimize therapeutic regimens, making pathology an integral part of so-called personalized medicine. In the future, recognition of early pathological conditions as well as individual molecular parameters will increase in importance. In addition, pathology has an essential role in regenerative medicine, which aims at stimulating healing processes in the various organs and tissues. As in the past, pathology must make its contribution to understanding of the mechanisms underlying defective repair, and discovery of new pathways for tissue regeneration. The latter is a principal research focus of the institute, and therefore we are happy to have internationally recognized scientists from this field for the first day of the symposium. Since cell and tissue banking is a crucial issue not only in pathology research but also in regenerative medicine the second day of the symposium is dedicated to that theme, which will also be presented by a group of leading international scientists. We hope that you will find inspiring moments at the symposium, and we thank all of our speakers and the institutions which supported this meeting! Univ.-Prof. C.J. Kirkpatrick, MD, PhD, DSc, FRCPath OA PD Dr. C. Brochhausen 2

3 Scientific Program Thursday 21 th May 2015 Pathology: working at the interface - past, present and future 8:30 J. Brahms Sonata for piano and violine A-dur op. 100 (Allegro amabile -Allegretto grazioso) U. Koneffke (piano), S. Stoodt (violin) 8:45 Welcome & Opening of the Symposium Prof. C. J. Kirkpatrick, MD, PhD, DSc, FRCPath () 8:50 Welcome address: Ministry of Education, Science and Culture Prof. T. Deufel, MD () 9:00 Welcome address: President of the Johannes Gutenberg-University Prof. W. Hofmeister, PhD DSc () 9:10 Welcome address: Dean of the Medical Faculty Prof. U. Förstermann, MD, PhD () 9:20 Welcome address from Scientific Attachée of the French Embassy Berlin Prof. Jolanta Lewandowska, PhD (Montpellier, France) 9:30 The history of the Institute of Pathology in Mainz Prof. P. G. Hochgesand, MD () 9:50 REPAIR-lab Life at the Interface Prof. C. J. Kirkpatrick, MD, PhD, DSc, FRCPath () 10:10 Art is I Science is WE Prof. H. Ringsdorf, PhD () Coffee-Break Development of biomaterials : interface between engineering and the life sciences 11:00 Designing complex biomaterials for the skeletal system Prof. L. Ambrosio, PhD (Naples/Rome, Italy) 11:30 Polymer therapeutics as nanomedicines for tissue repair Prof. Ruth Duncan, PhD (Cardiff, UK) 12:00 Tissue reactions to biomaterials Prof. P. A. Revell, MD, PhD, FRCPath (London, UK) Lunch Break Clinical applications the interface between repair and regenerative pathology 14:00 Tissue engineering & regenerative medicine: getting back to Nature Prof. R. L. Reis, PhD, DSc, MD (h.c.) (Minho, Portugal) 14:30 Tissue engineering in orthopedic surgery Prof. M. Brittberg, MD, PhD (Göteborg, Sweden) 15:00 Regenerative pathology in orthopedic surgery Priv.-Doz. Dr. C. Brochhausen, MD () Coffee-Break 3

4 Funding and networking the interface between science and economics 16:00 A road-map for a center of excellence in regenerative medicine Prof. R. L. Reis, PhD, DSc, MD (h.c) (Minho, Portugal) 16:30 The development of tissue engineering and regenerative medicine in France Meadhbh Brennan, PhD (Nantes, France) 17:00 Summary and closing remarks Prof. C. J. Kirkpatrick, MD, PhD, DSc, FRCPath () Friday 22 th May 2015 Tissue Banking Challenge for pathology at the interface between clinic and laboratory 9:00 Challenges and boundaries of pathology tissue banking P. H. J. Riegman, PhD (Rotterdam, NL) 9:30 Cryobiology and tissue banking Prof. Birgit Glasmacher, PhD (Hannover, Germany) 10:00 Ontologies and the semantic integration of biobank data Dr. M. Brochhausen, (Little Rock, USA) 10:30 A new fully automated and integrative Tissue bank system Priv.-Doz. Dr. C. Brochhausen () Coffee-Break Biobanking Multidisciplinary Networking at the Interface 11:30 Quality control in biobanks Prof. M. Neumaier, MD (Mannheim, Germany) 12:00 Creating a biobanking centre: the interface between national and international M. Divers, PhD (Stockholm, Sweden) 12:30 Networking for biobanking Prof. M. Hummel, PhD (Berlin, Germany) 13:00 End of the symposium 4

5 Speakers of the Symposium (in alphabetical order) Prof. L. Ambrosio, PhD Department of Chemical Sciences & Materials Technology National Research Council of Italy Rome, Italy Meadhbh Brennan, PhD Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Inserm UMR 957 Univeristy of Nantes Nantes, France Prof. M. Brittberg, MD, PhD Cartilage Research Unit, University of Gothenburg Region Halland Orthopaedics Kungsbacka Hospital Kungsabacka, Sweden Priv.-Doz. Dr. C. Brochhausen, MD Group Leader Cartilage Tissue Engineering Head of Electron Microscopy REPAIR-lab, Institute of Pathology, University Medical Centre of The Johannes Gutenberg-University Dr. phil. M. Brochhausen Assistant Professor, Division of Medical Informatics Interim Associate Director of the Translational Research Institute s Comprehensive Informatics Resource Center University of Arkansas for Medical Sciences Little Rock, USA M. Divers, PhD Director KI Biobank and BBMRI.se Biobank Service Facility Karolinska Institutet Stockholm, Sweden Prof. Ruth Duncan, PhD Professor of Cell Biology and Drug Delivery Professor Emerita Cardiff University Cardiff, UK Prof. P. G. Hochgesand, MD Descendant of the donator of the Institute of Pathology Jacob Hochgesand ( ) Prof. Birgit Glasmacher, PhD Institute for Multiphase Processes & Center for Biomedical Engineering Leibniz University Hannover Hannover, Germany 5

6 Prof. M. Hummel, PhD Institute of Pathology BBNRI-de German Biobank Node Charite -University Medicine Berlin Campus Benjamin Franklin Berlin, Germany Prof. C. J. Kirkpatrick, MD, PhD, DSc, FRCPath Chair of Pathology REPAIR-lab, Institute of Pathology, University Medical Centre of The Johannes Gutenberg-University Prof. M. Neumaier, MD Director of the Institute of Clinical Chemistry University Medical Centre Mannheim Medical Faculty Mannheim of the Ruprecht-Karls- University of Heidelberg Mannheim, Germany Prof. P. A. Revell, MD, PhD, FRCPath Honorary Consultant, Royal Orthopaedic Hospital, Birmingham Professor Emeritus University College London London, UK Prof. R. L. Reis, CEng, MSc, PhD, DSc, MD (h.c) Director of the 3B s Research Group Biomaterials, Biodegradables and Biomimetics Dept. of Polymer Engineering, University of Minho Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine Minho, Portugal P. H. J. Riegman, PhD Head of the "Erasmus MC Tissue Bank" at the "Molecular Diagnostics" Department of Pathology Erasmus Medical Center, Rotterdam, NL H. Ringsdorf, PhD Professor Emeritus Department of Organic Chemistry Johannes Gutenberg-University 6

7 The symposium was supported by the following partners 7