Extended Classification System for Medical Applications of Additive Manufacturing

Transcription

1 AFPR Conference PARIS, June 24-27, 2013 Extended Classification System for Medical Applications of Additive Manufacturing Jukka Tuomi Research Director Aalto University, BIT Research Centre President Finnish Rapid Prototyping Association, FIRPA 1 Jukka Tuomi, Aalto-yliopisto

2 Classification Systems for AM Technology oriented [ASTM F42, ISO 10303] Binder jetting Directed energy deposition Material extrusion Material jetting Powder bed fusion Sheet lamination Vat photopolymerization Application oriented Prototyping Tooling Manufacturing 2 Jukka Tuomi, Aalto-yliopisto

3 Brand Names Stereolithography, SLA (3D Systems) Fused deposition modeling, FDM (Stratasys) Binder jetting (3D Systems/Z Corp.) Material jetting (Stratasys/Solidscape) PolyJet (Stratasys/Objet) Selective laser sintering, SLS (3D Systems/DTM) Direct metal laser sintering, DMLS (EOS) 3 Jukka Tuomi, Aalto-yliopisto

4 Industrial Applications Prototypes Tools Production components 4 Jukka Tuomi, Aalto-yliopisto

5 AM Process 1/2 3D-CAD - Ideas - Pro/E - Catia - SolidWorks -.stl file AM - SLA - SLS - DMLS - LOM - FDM -.stl file Layer wise manufacturing Physical part 5 Jukka Tuomi, Aalto-yliopisto

6 AM Process 2/2 3D Model AM process Physical part 6 Jukka Tuomi, Aalto-yliopisto

7 Why AM? Rapid Prototypig Rapid Tooling Rapid Manufacturing Additive Manufacturing, AM SuperMachines Time to market Faster Ramp-up Agile manufacturing and customization High-end products, production and logistics 7 Jukka Tuomi, Aalto-yliopisto

8 Classification of Medical Applications Inert implants Pre- and postoperative models Medical aids and Supportive guides [J. Puokens] Tools and instruments [Tsinghua University] Biomanufacturing 8 Jukka Tuomi, Aalto-yliopisto

9 Models for Pre- and Postoperative Planning, Education, and Training 9 Jukka Tuomi, Aalto-yliopisto

10 Medical Aids, Supportive Guides, Splints and Prostheses 10 Jukka Tuomi, Aalto-yliopisto

11 11 Jukka Tuomi, Aalto-yliopisto

12 Tools, Instruments and Parts for Medical Devices [J. Puokens] 12 Jukka Tuomi, Aalto-yliopisto

13 Inert Implants 13 Jukka Tuomi, Aalto-yliopisto

14 Biomanufacturing [Tsinghua University] 14 Jukka Tuomi, Aalto-yliopisto

15 Class Purpose Relation of AM'd piece to patient Preoperative models Plan or simulate surgical procedure; Educate students, patients and family, train surgeons No patient contact Primary description Requirements Other Based on patient geometry but magnification or miniaturization possible; Anatomical accuracy requirements depend on case Transportability, storability, behavior in process, haptic response requirements depend on case Medical aids, supportive guides, splints & prostheses Enhance healing from trauma, anomaly or defect External to body non invasive May be combined to standard devices to provide patient-specific fit; Long term and postoperative supports, (motion) guides and fixators Non-allergic if in contact with skin, mechanical and surface requiements depend on case Includes external prostheses and prosthetic sockets, personalized splints, drill-guiding microtables, orthopedic appliances and braces Tools, instruments & parts for medical devices Enable or improve the efficacy of a medical or surgical procedure Contact with body fluids, mucous membranes, tissues or organs for a limited time: Invasive but not implantable, Patient-specific dimensions and shapes may be incorporated; Sterilizable; No immediate toxicity or allergic reactions, no shedding of particles; mechanical and surface requirements depend on case Includes drill guides, specialty surgical instruments, orthodontic appliances Inert implants Tissue replacement Wholly or partly implanted, long term contact with body fluids, tissues or organs Biocompatible; will not change its characteristics (much) in vivo May attract cell adhesion on surface but mainly stays inactive; durability, mechanical properties, surface properties depend on case Strict material requirements, long approval processes; Includes dental applications: crowns & bridges Biomanu facturing Biologically active tissue replacement; organ manufacturing Incorporated into body Shape personalized to match tissue defect, porous structures, optimal morphology depends on cell type and application site Porous structures; Scaffolds must be cell growth conductive, inductive, resorbable, controlled Polymers, ceramics and composites; Freeform culture media in vitro; Additive manufacturing + tissue engineering; 15 Jukka Tuomi, Aalto-yliopisto

16 Medical AM Process 1 Medical Imaging and 3D Digitizing 2 3D Modeling 3 Additive Manufacturing 4 Finishing 5 Clinical Application 16 Jukka Tuomi, Aalto-yliopisto

17 Classification Extension MAAM Matrix 17 Jukka Tuomi, Aalto-yliopisto

18 Case Example 18 Jukka Tuomi, Aalto-yliopisto

19 Web Platform for MAAM 19 Jukka Tuomi, Aalto-yliopisto

20 Acknowledgements Ian Gibson, National University of Singapore Stephen Rouse, USA Antti Mäkitie, Risto Kontio, Jan Lindahl, Jari Salo, Helsinki University Central Hospital and University of Helsinki Juho Vehviläinen, Kaija-Stiina Paloheimo, Roy Björkstrand, Mika Salmi, Eero Huotilainen, Aalto University 20 Jukka Tuomi, Aalto-yliopisto

21 Thank you! Jukka Tuomi Jukka Tuomi, Aalto-yliopisto