Proprietary Cell lines - Category A

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1 Proprietary Cell s - Category A CLS Cell Lines Service Part of the CLS cell bank CLS has established cell s which represent very useful cell models for research studies, testing of bioactive and other substances, screening assays and many more applications. All of the cell s as listed below are the sole property of CLS Cell Lines Service. Table 1: Human proprietary cell s Name of cell Designation (Tissue-Disease) Cell description Growth A64 CLS Human submaxillary gland Adenoma cell Adenoma Adherent BV-173 Human Hematopoiesis Leukemia, pre B-cell cell C643 Human Thyroidea Carcinoma cell Anaplastic thyroid carcinoma, Epithelial Pre B-lymphocyte Suspension Adherent CERV-186 Human Cervix Carcinoma cell Squamous carcinoma Adherent CERV-196 Human Cervix Carcinoma cell Squamous carcinoma Adherent CERV-215 Human Cervix Carcinoma cell Squamous carcinoma Adherent CLS-117 Human Struma Sarcoma cell Polymorph ; fibroblasts CLS-145 Human Gastric papillary adenocarcinoma cell Adherent Epithelial Adherent CLS-354 Humane HNSCC (Mouth) cell Squamous epithelial Adherent CLS-439 Human Urinary bladder Epithelial cell Epitheloid Adherent CLS-54 Human Lung Epithelial cell Carcinoma Adherent Colo-60H Human Colon carcinoma cell Untreated adenocarcinoma Colo-680N Human Oesophagus Squamous cell carcinoma cell Squamous cell carcinoma Adherent Adherent Colo-94H Human colorectal adenocarcinoma cell Epithelial Adherent FAMPAC Human Pancreas Adenocarcinoma cell Epithelial Adherent FAMPAC-A Human Pancreas Adenocarcinoma cell Epithelial Adherent HB-CLS-1 Human Urinary bladder Carcinoma cell Epithelial Adherent HB-CLS-2 Human Urinary bladder Carcinoma cell Epithelial Adherent HBL-52 Human Meningioma cell Epithelial Adherent HHC6548 T1 M1 Human Colorectal Adenocarcinoma cell Epithelial H-Meso-1 Human Lung Mesothelioma cell Epithelial Adherent H-Meso-1A Human Lung Mesothelioma cell Epithelial monolayer HROBMC01 HROBML03 Human Colorectal Adenocarcinoma cell Human non-small cell Lung cancer (NSCLC) cell Epithelial Epithelial monolayer Page 1 of 7

2 Name of cell Designation (Tissue-Disease) Cell description Growth HROC103 T0 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC107 Human Colorectal Adenocarcinoma cell Epithelial HROC112 Met T0 M2 Human Colorectal Adenocarcinoma cell Epithelial HROC113 Human Colorectal Adenocarcinoma cell Epithelial HROC126 Human Colorectal Adenocarcinoma cell Epithelial HROC131 T0 M3 Human Colorectal Adenocarcinoma cell Epithelial HROC147Met Human Colorectal Adenocarcinoma cell Epithelial HROC147 T0 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC173 Human Colorectal Adenocarcinoma cell Epithelial HROC18 Human Colorectal Adenocarcinoma cell Epithelial HROC183 Human Colorectal Adenocarcinoma cell Epithelial HROC183 T0 M2 Human Colorectal Adenocarcinoma cell Epithelial HROC212 Human Colorectal Adenocarcinoma cell Epithelial HROC24 Human Colorectal Adenocarcinoma cell Epithelial HROC24 T1 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC257 Human Colorectal Adenocarcinoma cell Epithelial HROC257 T0 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC277 T0 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC277Met2 Human Colorectal Adenocarcinoma cell Epithelial HROC278 T0 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC278Met T2 M2 Human Colorectal Adenocarcinoma cell Epithelial HROC284Met Human Colorectal Adenocarcinoma cell Epithelial HROC285 T0 M2 Human Colorectal Adenocarcinoma cell Epithelial HROC296 Human Colorectal Adenocarcinoma cell Epithelial HROC309 Human Colorectal Adenocarcinoma cell Epithelial HROC313 Met Human Colorectal Adenocarcinoma cell Epithelial HROC32 Human Colorectal Adenocarcinoma cell Epithelial HROC324 Human Colorectal Adenocarcinoma cell Epithelial Page 2 of 7

3 Name of cell Designation (Tissue-Disease) Page 3 of 7 Cell description Growth HROC334 Human Colorectal Adenocarcinoma cell Epithelial HROC357 Human Colorectal Adenocarcinoma cell Epithelial HROC364 Human Colorectal Adenocarcinoma cell Epithelial HROC374 Human Colorectal Adenocarcinoma cell Epithelial HROC39 Human Colorectal Adenocarcinoma cell Epithelial HROC40 Human Colorectal Adenocarcinoma cell Epithelial HROC43 Human Colorectal Adenocarcinoma cell Epithelial HROC46 T0 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC50 T1 M5 Human Colorectal Adenocarcinoma cell Epithelial HROC57 Human Colorectal Adenocarcinoma cell Epithelial HROC59 T1 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC60 Human Colorectal Adenocarcinoma cell Epithelial HROC69 Human Colorectal Adenocarcinoma cell Epithelial HROC69 T0 M2 Human Colorectal Adenocarcinoma cell Epithelial HROC80 T1 M1 Human Colorectal Adenocarcinoma cell Epithelial HROC87 T0 M2 Human Colorectal Adenocarcinoma cell Epithelial HROG02 Human Glioblastoma cell Fibroblastoid Adherent HROG04 Human Glioblastoma cell Fibroblastoid Adherent HROG05 Human Glioblastoma cell Fibroblastoid with long HROG06 Human Glioblastoma cell Fibroblastoid with long HROG07 Human Glioblastoma cell Astrocytic, small body and long HROG10 Human Glioblastoma cell Astrocytic, small body and long HROG13 Human Glioblastoma cell Fibroblastoid with long Adherent Adherent Adherent Adherent Adherent HROG15 Human Glioblastoma cell Epitheloid Adherent HROG17 Human Glioblastoma cell Epitheloid Adherent HROG36 Human Glioblastoma cell Astrocytic, small body and long Adherent HROGas03 Human Gastric carcinoma cell Epithelial Adherent HROHep03 Human Hepatoma cell Epithelial Adherent MA-CLS-2 Human Breast cancer cell Epithelial Adherent MEL-CLS-1 Human Melanoma cell Triangular Adherent

4 Name of cell Designation (Tissue-Disease) Cell description Growth MEL-CLS-2 Human Melanoma cell Triangular Adherent MEL-CLS-3 Human Melanoma cell Elongated Adherent MEL-CLS-4 Human Melanoma cell Triangular Adherent MHH-ES1 Human Bone Ewing s sarcoma cell Epitheloid Adherent MML-1 Human Melanoma cell Elongated, Adherent MX-1 Human Breast cancer cell Epitheloid Adherent NIS-G Human Melanosarcoma cell Triangular and elongated Adherent RC-124 Human Kidney (adult) primary cell Epithelial Adherent RCC-ER RCC-FG1 RCC-FG2 RCC-GH RCC-GS RCC-HB RCC-JF RCC-JW RCC-KL RCC-KP RCC-LR RCC-MF RCC-MH RCC-OF1 RCC-PR RCC-WK Epitheloid Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent Epithelial Adherent RT-112-D21 Human Urinary bladder carcinoma cell Epithelial Adherent SW-1736 Human Thyroidea carcinoma cell Epitheloid Adherent U-343 MG Human Glioblastoma cell Epithelial Adherent WS1 Human Skin embryonal fibroblastoid cell Fibroblastoid Adherent WT-CLS1 Human Kidney (Wilms Tumor) cell Epithelial Adherent Page 4 of 7

5 Table 2: Animal proprietary cell s Name of cell Designation Cell type Cell type Growth Page 5 of 7 AH-130 Rat Liver Hepatoma cell Epithelial-like Adherent AH-130 FN Rat Liver Hepatoma cell Epithelial-like Suspension AS-30D Rat Liver Hepatoma cell Round cell, some in clusters Adherent ASB-XIV Murine Lung Carcinoma cell Epithelial Adherent AT-1 Rat Prostate Adenocarcinoma cell -- Adherent CaD2 Murine Breast Carcinoma cell Epithelial Adherent CDNR4 Murine Breast Adenocarcinoma cell Epithelial Adherent CLS-103 Murine Stomach Squamous cell Carcinoma cell Epithelial Adherent CLS-138 Murine Skin Sarcoma spindel cell Fibroblastoid Adherent CLS-ACI-1 Rat Breast Adenocarcinoma cell Epitheloid Adherent CLS-CD-3575 Murine Renal Carcinoma cell Epitheloid/Fibroblastoid Adherent Colon-26 Mouse (from CT-26 mouse model) Murine Colon Carcinoma cell Epithelial Adherent E11 Murine Kidney podocyte cell Epithelial Adherent ECF-R Chicken Embryo Fibroblastoid cell not available at the moment EGG Murine Hematopoiesis Leukemia cell Round lymphocytic Fibroblast Adherent Suspension FS-Balb Murine Fibrosarkom cell Fibroblast Adherent FS-C3H Murine Skin Fibrosarcoma cell Fibroblast Adherent FS-C57BL Murine Skin Sarcoma cell Fibroblast Adherent HB-CLS-3 Rat Urinary bladder carcinoma cell Squamous carcinoma Adherent Hep-53.4 Murine Liver Hepatoma cell Epithelial Adherent Hep-55.1C Murine Liver Hepatoma cell Epithelial Adherent Hep-56.1B Murine Liver Hepatoma cell Epithelial Adherent Hep-56.1C Murine Liver Hepatoma cell Epithelial Adherent Hep-56.1D Murine Liver Hepatoma cell Epithelial Adherent Hep-64.1 Murine Liver Hepatoma cell Epithelial Adherent Hep-66.3A Murine Liver Hepatoma cell Epithelial Adherent Hep-70.4 Murine Liver Hepatoma cell Epithelial Adherent Hep-74.3A Murine Liver Hepatoma cell Epithelial Adherent Hep-CLS-1H Murine Liver Hepatoma cell Epithelial Adherent Hep-CLS-1W Murine Liver Hepatoma cell Epithelial Adherent Hep-CLS-C9 Murine Liver Hepatoma cell Epithelial Adherent

6 Name of cell Designation Cell type Cell type Growth Hep-CLS-E1 Murine Liver Hepatoma cell Epithelial Adherent KERA-308 Murine Keratinocyte cell Keratinocyte Adherent KERA-SP1 Murine Keratinocyte cell Keratinocyte Adherent LS-CLS Hamster Hematopoiesis Lymphosarcoma cell Round lymphocytic Suspension MA-Balb Murine Breast Carcinoma cell Epithelial Adherent MCA-3D Murine Keratinocyte cell Keratinocyte Adherent MDCC-MSB1 Chicken Lymphoblast cell Meth A Sarcoma Murine Skin Sarcoma cell Round lymphocytic Round lymphocytic, slightly adherent Suspension Suspension / Adherent MH-3924A Rat Liver Hepatoma cell Epitheloid Adherent MH-TC-5123 Rat Liver Hepatoma cell Epitheloid Adherent MSC-P5 Murine Keratinocyte cell Keratinocyte Adherent NFS-60 Murine myeloid Leukemia cell Round lymphocytic Suspension NIH-3T3-RAS Murine Embryo Fibroblast, RAS+ cell Fibroblast Adherent Novikoff- Hepatoma Rat Liver Hepatoma cell Round Suspension O-342 Rat Ovary Adenocarcinoma cell Round with OCD Murine Osteochondroma cell Chondrocytic, fibroblastoid Adherent Adherent OS1-CLS Rat Bone Osteosarcoma cell Epithelial Adherent PCC4-aza1 Murine Testis Teratocarcinoma cell Epithelial Adherent PDV Murine keratinocyte cell Keratinocyte Adherent PECA Murine Skin squamous cell carcinoma cell Epitheloid Adherent RenCa-IL2 Murine Renal carcinoma cell Epithelial Adherent RY(ham) Yoshida sarcoma Rat Fibroblast sarcoma cell Round slightly adherent Suspension / Adherent SAT Murine Breast adenocarcinoma cell Epithelial Adherent SVI Murine Kidney podocyte cell Epithelial Adherent TERA-C3H Murine Ovary teratoma cell Epithelial Adherent TRI-C3H Murine Skin trichoepithelioma cell Epithelial Adherent Zajdela- Hepatoma ZH- CLS Rat Liver hepatoma cell Epithelial Adherent Information on cell culture conditions, authentication data, cell morphologies and more can be found on the website: Page 6 of 7

7 Cell s of Category A: CLS proprietary cell s Use in Internal Research The proprietary cell s listed above have been established by CLS itself or have been deposited at and donated to CLS. These cell s of Category A are available without the need to complete and sign a MTA, if the cell s are intended for Research purposes. The ultimate goal of a research application is the publication in a scientific journal of appropriate impact. With respect to cell s of Category A, the General Terms and Conditions of Supply of CLS Cell Lines Service GmbH apply. According to the Terms, the products are not intended to be resold and/or modified for resale. Licensing conditions All cell s of Category A can be acquired for Commercial applications. The MTA represents the agreement between the for-profit customer and CLS. Applications including a commercial interest are: use of cell s in manufacturing, in providing services, information and data, for therapeutic, diagnostic or prophylactic purposes and for resale. Please contact us via service@clsgmbh.de or info@clsgmbh.de if there are further questions regarding the commercial use of CLS proprietary cell s. Distributing conditions Acting as Distributor of cell s of Category A is allowed if CLS has approved it in writing. Page 7 of 7