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2 SERVING SOCIETY THROUGH SCIENCE POLICY Advance Registration Now Open The 2017 meeting will focus on how to inform policies with the best available scientifc evidence. Register for the meeting and reserve a room now to receive lower rates. Join thousands of leading scientists, educators, policymakers, and journalists in Boston to discuss recent developments in science, technology, and policy. Advance registration is available online. aaas.org/meetings AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE

3 The Industry s Preeminent Event on Novel Drug Targets 14th Annual Science & Diplomacy provides an open access forum for rigorous thought, analysis, and insight to serve stakeholders who develop, implement, or teach all aspects of science and diplomacy. Learn more about the latest ideas in science diplomacy and receive regular updates by on Twitter, liking the quarterly s page on Facebook ( sciencediplomacy), and registering for free at org/user/register. SEPTEMBER 19-22, 2016 BOSTON, MA WESTIN BOSTON WATERFRONT CONFERENCE PROGRAMS SEPTEMBER Targeting Histone Methyltransferases and Demethylases Targeting the Ubiquitin Proteasome System Targeting the Microbiome - Part 1 GPCR-Based Drug Discovery - Part 1 Advances in Gene Editing and Gene Silencing - Part 1 Gene Therapy Breakthroughs Antibodies Against Membrane Protein Targets - Part 1 Targeting Cardio-Metabolic Diseases Targeting Ocular Disorders SEPTEMBER Targeting Epigenetic Readers and Chromatin Remodelers Kinase Inhibitor Discovery Targeting the Microbiome - Part 2 GPCR-Based Drug Discovery - Part 2 Advances in Gene Editing and Gene Silencing - Part 2 Translating Cancer Genomics Antibodies Against Membrane Protein Targets - Part 2 Metabolomics in Drug Discovery SEPTEMBER TRAINING SEMINAR: Data Visualization SYMPOSIA SEPTEMBER 19 Science & Diplomacy is published by the Center for Science Diplomacy of the American Associaton for the Advancement of Science (AAAS), the world s largest general scientfc society. Next-Generation Histone Deacetylase Inhibitors Strategies for Tackling Rare Genetic Diseases Understanding CRISPR: Mechanisms and Applications Autoimmunity Small Molecule Approaches NK Cell-Based Cancer Immunotherapy REGISTER TODAY! Reference key code L35 when registering DiscoveryOnTarget.com

4 myidp: A career plan customized for you, by you. For your career in science, there s only one Features in myidp include: Recommended by leading professional societies and the NIH Exercises to help you examine your skills, interests, and values. A list of 20 scientific career paths with a prediction of which ones best fit your skills and interests. A tool for setting strategic goals for the coming year, with optional reminders tokeepyouontrack. Articles and resources to guide you through the process. Options to save materials online and print them for further review and discussion. Ability to select which portion of your IDP you wish to share with advisors, mentors, or others. A certificate of completion for users that finish myidp. Visit the website and start planning today! myidp.sciencecareers.org In partnership with:

5 Produced by the Science/AAAS Custom Publishing Office LIFE SCIENCE TECHNOLOGIES NEW PRODUCTS FT-NIR Spectrometer For small business owners, technicians, laboratory managers, and method developers, a new Fourier transformnear infrared (FT-NIR) spectrometer is designed to bring rapid and reliable analysis for quality control and material uses the same proprietary software platform found across the entire Nicolet Lite software supports routine system operation, and the TQ Analyst EZ or Pro software can be used for calibration graphic user interface provided by the is a workhorse technique for materials tool designed to meet the needs of busy NIR technology and proven IR analysis ddpcr Multiplex Mutation Screening Kit for detecting several key actionable cancer mutations and the wild-type allele increases the throughput of genetic analysis and allows clinical researchers enables the detection of rare nucleic acid competing sequences, while minimizing The kits identify mutations present at allelic frequencies at or Bio-Rad Confocal Laser Scanning Microscope cal laser scanning microscope for materials applications and analysis in - - of nanomaterials, metals, polymers, the investigation of nanometer-scale structures without causing surface - gation (ZEN) imaging software, which includes an open application develop- established third-party analysis and Zeiss Bioinformatics Software ates genomic data analysis for sequence to-answer informatics infrastructure to enable precision medicine and genomics - comprehensive platform, from laboratory information management, analysis, and sharing to sample interpretation, reporting, and advanced cohort analyt- It improves the overall accuracy of results without the need to integrate point solutions from multiple vendors, and is ideal for numerous labs, including clinical and ready, providing a secure, scalable solution, simplifying data storage issues, and providing a highly collaborative environ- pipe user-friendly for a myriad of clientsófrom the clinical scientist to the lab director and Illumina Carbon/Sulfur Analyzers - measurement capabilities, optimizing their the analyzers can be used for a wide variety of inorganic materials such as steel, cokes, catalysts, nonferrous alloys like alu- new cleaning mechanism allows increased mechanism enables users to repeat their new, robust design with fewer components enables more reliable use and less service - system that recommends the most suitable conditions for samples, Electronically submit your new product description or product literature information! Go to for more information. Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier. SCIENCE sciencemag.org/custom-publishing 12 AUGUST 2016 VOL 353 ISSUE

6 Image: jim /AdobeStock Be Among the First to Publish in Science Robotics NOW ACCEPTING MANUSCRIPTS ScienceRobotics.org Science Robotics is a unique journal created to help advance the research and development of robotics for all environments. Science Robotics will provide a much-needed central forum to share the latest technological discoveries and to discuss the feld s critical issues. Join in the excitement for the Fall 2016 debut!

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