Symposium Enzymes and enzyme complexes acting on nucleic acids

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1 Symposium Enzymes and enzyme complexes acting on nucleic acids of the International Research Training Group Gießen/Marburg Moscow (DFG/RFBR funded) 14th and 15th September 2015 Aula of the Justus Liebig University Gießen

2 Programme Monday 14 th of September h Welcome Address Joybrato Mukherjee (JLU president) Session 1 (Chair: Kristina Kovač) 9.10 h Jane Mellor, Oxford, UK Transcription and RNA Fate h Sergey Ulianov, Moscow, RUS Epigenetic landscapes underlying partitioning of eukaryotic chromosomes into topologically associating domains h Coffee/Tea Break Session 2 (Chair: Julia Hahn) h Olga Zanegina, Moscow, RUS In search of conserved features in protein NA complexes: examples of usage of Nucleic acid Protein Interaction DataBase (NPIDB) h Albrecht Bindereif, Gießen Circular RNAs, a new class of noncoding RNAs h Patrick Cramer, Göttingen Transcription of the genome: from molecules to systems h Lunch and Posters Session 3 (Chair: Maya Monakhova) h Sofia Georgieva, Moscow, RUS AMEX/TREX 2 mrna nuclear export complex in Drosophila h Maximilian Reuter, Gießen The polya binding protein Nab2 functions in RNA polymerase III transcription h Utz Fischer, Würzburg Mechanistic dissection of the early phase of UsnRNP biogenesis uncovers a role of ribosomes in assembly and RNP homeostasis h Coffee/Tea Break

3 Session 4 (Chair: Tim Schneider) h Stefanie Dimmeler, Frankfurt Non coding RNAs in cardiovascular disease h Renée Schroeder, Wien, A RAPs RNA polymerase binding Aptamers that control transcription in cis h Speakers Dinner Tuesday 15 th of September 2015 Session 5 (Chair:Julia Gotthardt) 9.00 h Titia Sixma, Amsterdam, NL Snapshots of DNA mismatch repair: trapping transient states 9.50 h Olga Lavrik, Novosibirsk, RUS Poly(ADP ribose) polymerase 1 as regulator of DNA repair and target for anticancer drug development h Coffee/Tea Break Session 6 (Chair: Fabian Bietz) h Pingping Li, Gießen Conformational changes of the MMR Protein MutL studied by FRET h Eric Westhof, Strasbourg, F Isostericity, Tautomerism and Geometric Selection of Nucleic Acid Base Pairs h Laura Waltl, Gießen Talented nucleases: Characterization of highly specific nucleases in vivo h Lunch Session 7 (Chair: Katrin Damm) h Ivan Shatsky, Moscow, RUS Glycyl trna synthetase modulates eif4g activity to promote the correct initiation of translation on type I picornavirus IRESes h Nadine Wäber, Marburg The last mystery of trna processing Identification and characterization of the RNase P of the hyperthermophilic bacterium Aquifex aeolicus

4 14.30 h Michael Niepmann, Gießen Control of Hepatitis C Virus Replication h Roland Hartmann, Marburg Ebola Virus VP30 Binding to RNA is essential for activating viral transcription h Coffee/Tea Break Session 8 (Chair: Katrin Müller) h Jørgen Kjems, Aarhus, DK Roles of microrna and circular RNA for development and disease in mammalian brain h Olga Burenina, Moscow, RUS 6S 1 and 6S 2 RNAs from B. subtilis: from mechanistic research to understanding of their functional roles in vivo h Ling Ling Chen, Shanghai, China Noncoding RNAs with new formats: discovery, biogenesis and functional implication h Concluding Remarks Peter Friedhoff, Tatiana Oretskaya

5 Poster Session Poster No. Name group 1 Kathrin Baumgardt Evguenieva Hackenberg 2 Fabian Bietz Wende 3 Priyanka Bodapati Renkawitz 4 Ganesh Bylapudi Ziebuhr 5 Katrin Damm Hartmann 6 Nadia Dünnes Niepmann 7 Susann Gauernack Klug 8 Julia Gotthardt Friedhoff 9 Julia Hahn Evguenieva Hackenberg 10 Henrik Koch Bindereif 11 Kristina Kovač Brehm 12 Maya Monakhova Kubareva/Oretskaya 13 Katrin Müller Klug 14 Anika Nieder Röhrmann Niepmann 15 Bernhard Remes Klug 16 Ivan Rusinov Alexeevski 17 Lyudmila Shalamova Niepmann 18 Nadine Wäber Hartmann 19 Lennart Weber Klug A1 LOEWE Tim Schneider Bindereif