Structure of Biological Materials

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1 ELEC ENG 3BA3: Structure of Biological Materials Notes for Lecture #1 Friday, September 7, 2012

2 Instructor: Dr. Ian C. Bruce Room ITB-A213, Ext (or alias not both). Office Hours: T.B.A. Teaching Assistant: Stephanie Cheung Room ETB-301/303A, Ext Office Hours: T.B.A. Web Site: 2

3 Course mailing list: This mailing list will be used as a primary means of communication for this course please make sure that you check your regularly! Only for instructor and TA use If you are not currently on this mailing list, please me with your name, student number and address. 3

4 COURSE OBJECTIVES: 1. to provide an introduction to bioengineering from a basis of the structure and function of biological materials; 2. to examine the structural foundations of several biomedical engineering technologies that will be studied in later courses; and 3. to give an introduction to bioengineering topics beyond the focus of the Electrical and Biomedical Engineering program. 4

5 Course Content: Introduction to Bioengineering Biomaterials (topic #1) Biomechanics (topic #2) Physiological Fluid Mechanics (topic #3) Drug Delivery, Biosensors and Artificial Organs (topic #4) Foundations for Medical Imaging (topic #5) 5

6 Textbooks: Required text: S. V. Madihally, Principles of Biomedical Engineering, Artech House, (Hardcopies are available at Titles Bookstore. Electronic version also available from publisher Artech House.) 6

7 Textbooks: 1 st alternative text: S. A. Berger, E. W. Goldsmith, and E. R. Lewis, Introduction to Bioengineering, Oxford University Press,

8 Textbooks: 2 nd alternative text: J. Enderle, S. Blanchard, and J. Bronzino, Introduction to Biomedical Engineering (2nd ed.), Academic Press,

9 Classes: There will be 48 one-hour classes (3 lectures + 1 tutorial per week) on: Mondays at 10:30 11:20am in T & at 11:30am 12:20pm in T13-105, Wednesdays at 11:30am 12:20pm in T and Fridays at 1:30 2:20pm in T These scheduled class times will be used for a mixture of lectures, class discussions, tutorials, and student presentations. Lecture notes in PDF format will be posted on the course web site. 9

10 Class Pattern: The schedule for the term will have the following structure: Lectures and tutorials on topics #1 & #2 Student presentations on topics #1 & #2 Midterm #1 Lectures and tutorials on topics #3 & #4 Student presentations on topics #3 & #4 Midterm #2 Lectures and tutorials on topic #5 Student presentations on topic #5 Final Exam 10

11 You will: Project presentations: work in pairs; review a particular biomedical engineering research area, technology, or application; give a 25-minute presentation, including time for questions and discussion. (The topic cannot be the same as a presentation from last year s class.) 11

12 Assessment: Project presentations (20%) Midterm quizzes (2 20% = 40%) Final exam (40%) 12

13 Course Policies: Calculator Requirement for Tests and Exams: McMaster Standard Calculator (Casio fx991) only Deferred Exam Format: The instructor reserves the right to choose the format (i.e., written or oral) of any deferred midterm or final exam in this course. Announcements re. graded material: Please note that announcements concerning any type of graded material may be in any format (e.g., announcements may be made only in class, via the course ing list, or on the course web site). Students are responsible for completing the graded material regardless of whether they received the announcement or not. 13

14 Policy Reminders: The Faculty of Engineering is concerned with ensuring an environment that is free of all adverse discrimination. If there is a problem, that cannot be resolved by discussion among the persons concerned, individuals are reminded they should contact the Departmental Chair, the Sexual Harassment Officer or the Human Rights Consultant, as soon as possible. Academic dishonesty consists of misrepresentation by deception or by other fraudulent means and can result in serious consequences, e.g. the grade of zero on an assignment, loss of credit with a notation on the transcript (notation reads: 'Grade of F assigned for academic dishonesty'), and/or suspension or expulsion from the university. It is your responsibility to understand what constitutes academic dishonesty. For information on the various kinds of academic dishonesty please refer to the Academic Integrity Policy, specifically Appendix 3, located at The following illustrates only three forms of academic dishonesty: 1. Plagiarism, e.g. the submission of work that is not one s own or for which other credit has been obtained. 2. Improper collaboration in group work. 3. Copying or using unauthorized aids in tests and examinations. 14

15 Example presentation topics: Biomaterials:- Repair of Articular Cartilage in Knee Joints Contact Lenses Heart Valves Materials Used in Bone Repair Biomaterials for Skin Grafting Biomaterials for Cochlear Implants Biomaterials for Nerve Repair: Nerve Guides 15

16 Example topics (cont.): Biomechanics:- Functional Electrical Stimulation Titanium Foam Implants The Bionic Arm Biomechanics of Knee Replacement Powered Ankle Foot Prosthesis Biomechanics of Dental Implants Hand Prostheses Spine Cages Artificial Muscle Actuators for Upper Limb Prostheses Crash Test Dummies 16

17 Example topics (cont.): Physiological Fluid Mechanics:- Medical Ventilators Lymphedema Microgravity and the Circulatory System Heart-Lung Machines Cardiac Pacemakers 17

18 Example topics (cont.): Drug Delivery, Biosensors & Artificial Organs:- Artificial Lungs Artificial Liver Anesthesia Optical Biosensors Microelectromechanical Drug Delivery Systems Scaffold Design & the Artificial Bladder Nano Biosensors & Cancer Detection DNA & Protein Biosensors 18

19 Example topics (cont.): Medical Imaging:- Capsule Endoscopy Electrical Impedance Tomography Fluorescence Imaging Cone Beam CT MRI Angiography Diffusion Weighted MRI Cancer Imaging for Soft Tissue Targeted Imaging 3D & 4D Ultrasound 19