Bioengineering Research Map

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Bioengineering Research Map Lee Makowski, Professor and Chair l.

edu Mark Niedre, Associate Professor and Associate Chair For Research m.

1 Bioengineering Research Map Lee Makowski, Professor and Chair Mark Niedre, Associate Professor and Associate Chair For Research Chloe Tolman, @nubioe

Ambika Bajpayee Molecular Electrostatics &

biomechanics; mechanisms underlying trauma

2 Ambika Bajpayee Molecular Electrostatics & Drug Delivery Lab Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Area 3: Molecular, Cell, and Tissue Engineering Research Interests: Targeted delivery of drugs and imaging probes; bio-electrostatics; bio-transport modeling; biomechanics; mechanisms underlying trauma and age induced osteoarthritis Lab website: Teaching: BIOE 5650 Multiscale Biomechanics; BIOE 5651 Fields Forces and Flows

Anand Asthagiri Associate Professor of Bioengineering Affiliated Professor of Biology and Chemical Engineering a.asthagiri@northeastern.

integrative, predictive principles for engineering mammalian cell behaviors and multicellular morphodynamics, with applications in cancer

3 Anand Asthagiri Associate Professor of Bioengineering Affiliated Professor of Biology and Chemical Engineering Research Area 3: Molecular, Cell and Tissue Engineering Research Area 4: Computational and Systems Biology Research Interests: integrative, predictive principles for engineering mammalian cell behaviors and multicellular morphodynamics, with applications in cancer and regenerative medicine. Lab Website: Teaching: BIOE3380 Biomolecular dynamics and control, BIOE5420 Cellular Engineering

Chiara Bellini, Ph. D. Affiliated Faculty, Mechanical and Industrial Engineering c.

edu Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Area 4:

growth & remodeling of tissues and organs; thoracic aortic aneurysms; arterial stiffness;

4 Chiara Bellini, Ph. D. Affiliated Faculty, Mechanical and Industrial Engineering Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Area 4: Computational and Systems Biology Research Interests: Cardiovascular mechanics; cell-mediated growth & remodeling of tissues and organs; thoracic aortic aneurysms; arterial stiffness; vascular/skeletal systems interaction; effect of chronic aerosol inhalation on cardiovascular function Publications: Teaching: BIOE 2350 Biomechanics

Eduardo D. Sontag Distinguished University Professor Electrical and Computer Engineering and Bioengineering Faculty, Program in Therapeutic Science, Harvard Medical School e.

edu Research Area 3: Molecular, Cell, and Tissue Engineering Research Area 4: Computational and Systems Biology Research Interests: Systems and Synthetic Biology, Control Systems

5 Eduardo D. Sontag Distinguished University Professor Electrical and Computer Engineering and Bioengineering Faculty, Program in Therapeutic Science, Harvard Medical School Research Area 3: Molecular, Cell, and Tissue Engineering Research Area 4: Computational and Systems Biology Research Interests: Systems and Synthetic Biology, Control Systems in Biology and Engineering, Biocomputing, Immune/Tumor Interactions, Optimal Control of Cancer Therapy, Phenotypic Resistance, Reverse Engineering Cell Signaling, and Gene Networks, Resource Competition in Cells. Publications: Teaching: BIOE 5115 Dynamical Systems in Biological Engineering

Molecular, Cell, and Tissue Engineering Research Interests: Vascular Tissue Engineering,

6 Guohao Dai Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Area 3: Molecular, Cell, and Tissue Engineering Research Interests: Vascular Tissue Engineering, Stem Cell Engineering, 3D Bioprinting Publications: Teaching: Physiological Fluid Mechanics

Hari Parameswaran, Ph. D. h.parameswaran@northeastern.

Interests: Mechanotransduction, multiscale mechanobiology, Computational modeling, Cell-Cell communication, [Current:] Dynamic switching of

7 Hari Parameswaran, Ph. D. Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Area 3: Molecular, Cell, and Tissue Engineering Research Interests: Mechanotransduction, multiscale mechanobiology, Computational modeling, Cell-Cell communication, [Current:] Dynamic switching of force transmission pathways in multicellular ensembles Publications: Teaching: GE 2361 Mathematical methods for Engineers; BIOE 5060 Mechanotransduction in cells & tissue

Heather Clark Professor, Bioengineering and Chemistry Director, Institute for Chemical Imaging of Living Systems h.clark@northeastern.

of chemistry and biology to develop and apply novel nanoscale probes for bio measurements.

8 Heather Clark Professor, Bioengineering and Chemistry Director, Institute for Chemical Imaging of Living Systems Research Area 1: Imaging, Instrumentation, and Signal Processing Research Interests: My group is currently working at the interface of chemistry and biology to develop and apply novel nanoscale probes for bio measurements. Ultimately, we will use nanosensors to image specific chemical processes in the body, in real-time. Publications:

Jeffrey Ruberti Professor of Bioengineering j.ruberti@northeastern.

Engineering Research Interests: My lab focuses on the role matrix molecules play in the transition of animals from a

The relevant disciplines are: Mechanochemistry, Mechanobiology, Mechanobioreactor Development, Cell Culture, Single

9 Jeffrey Ruberti Professor of Bioengineering Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Area 3: Molecular, Cell and Tissue Engineering Research Interests: My lab focuses on the role matrix molecules play in the transition of animals from a loosely-connected grouping of cells to a fully-connected, mechanically robust structure. The relevant disciplines are: Mechanochemistry, Mechanobiology, Mechanobioreactor Development, Cell Culture, Single Molecule Light Microscopy, High Resolution Electron Microscopy. Webpage: Teaching: Principles of Bioengineering, Quantitative Physiology, Capstone Design

Biomechanics Jessica M. Oakes Respiratory Innovation and Simulation Team j.

10 Publications: Teaching: Transport and Fluids for Bioengineers and Computational Biomechanics Jessica M. Oakes Respiratory Innovation and Simulation Team Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Area 4: Computational and Systems Biology

Lee Makowski Professor and Chair, Bioengineering l.makowski@northeastern.

as applied to biophysical data designed to answer fundamental questions about the molecular basis of living

11 Lee Makowski Professor and Chair, Bioengineering Research Area 3: Molecular, Cell, and Tissue Engineering Research Interests: Image and signal processing as applied to biophysical data designed to answer fundamental questions about the molecular basis of living systems. Publications: Teaching: Principles of Bioengineering, Molecular Bioengineering

Mark Niedre, Ph. D. Associate Professor of Bioengineering Associate Chair for Research and Graduate Studies m.niedre@northeastern.

Biomedical optics; fluorescence imaging; cancer metastasis; rare cell detection and tracking in the body; ultrafast light-tissue interactions; image

12 Mark Niedre, Ph. D. Associate Professor of Bioengineering Associate Chair for Research and Graduate Studies Research Area 1: Imaging, Instrumentation, and Signal Processing Research Area 3: Molecular, Cell, and Tissue Engineering Research Interests: Biomedical optics; fluorescence imaging; cancer metastasis; rare cell detection and tracking in the body; ultrafast light-tissue interactions; image reconstruction and signal processing Publications: Teaching: BIOE 3210 Bioelectricity; BIOE 5235 Biomedical Imaging

Nikolai Slavov Affiliated Faculty, Biology n.slavov@northeastern.

Interests: Rationally engineered directed differentiation, single-cell

signaling, systems biology Publications: northeastern.

13 Nikolai Slavov Affiliated Faculty, Biology Research Area 4: Computational and Systems Biology Research Interests: Rationally engineered directed differentiation, single-cell analysis, ribosome-mediated translational regulation, proteomics, cell signaling, systems biology Publications: northeastern.edu/slavovlab Teaching: Mathematical Methods for Engineers & Methods and Logic in Systems Biology

Qianqian Fang, Ph. D. q.fang@northeastern.

functional imaging Webpage: https://fanglab.org; http://mcx.

14 Qianqian Fang, Ph. D. Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Interests: Optical tomography, computational optics, point-of-care devices, brain functional imaging Webpage: Teaching: BioE 3210 Bioelectricity; 5235: Biomed. Imaging, 5810: Design of Biomed Instru.

Samuel Chung, Ph. D. s.chung@northeastern.

Research Area 3: Molecular, Cell, and Tissue Engineering Research

imaging; microscopy automation Webpage: https://sites.google.

15 Samuel Chung, Ph. D. Research Area 1: Imaging, Instrumentation, and Signal Processing Research Area 3: Molecular, Cell, and Tissue Engineering Research Interests: Axon regeneration; femtosecond laser surgery; fluorescence imaging; microscopy automation Webpage: Teaching: BIOE 2355 Quantitative Physiology; BIOE 5060 Introduction to Neurophotonics

Sandra Shefelbine Associate Professor of Bioengineering Associate

Research Interests: multi-scale mechanics of bones; adaptation of bone

16 Sandra Shefelbine Associate Professor of Bioengineering Associate Professor of Mechanical and Industrial Engineering Research Area 2: Biomechanics, Biotransport and MechanoBiology Research Interests: multi-scale mechanics of bones; adaptation of bone to mechanical loading during growth and ageing Publications: Teaching: ME 5665 Musculoskeletal Biomechanics; BIOE 2350 Biomechanics

Sara H. Rouhanifard s.rouhanifard@northeastern.

and Tissue Engineering Research Interests: Development of single-cell technologies for DNA+RNA, Nucleic acid

17 Sara H. Research Area 1: Imaging, Instrumentation, and Signal Processing Research Area 3: Molecular, Cell, and Tissue Engineering Research Interests: Development of single-cell technologies for DNA+RNA, Nucleic acid detection as a diagnostic tool, RNA modifications in developing neurons Publications: & Teaching: BIOE 3380