International Cooperation in Health Research and Life Sciences Modalities and Topics of next Call

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1 1 International Cooperation in Health Research and Life Sciences Modalities and Topics of next Call Dr Gianpietro van de Goor Directorate Health, DG Research European Commission Open Information Day Brussels, 8 June 2010

2 2 International Research Collaborations Priority for the EU - Opportunity for Researchers Diseases do not respect political or cultural borders, and affect both poor and rich countries Health is a political priority for most countries (rich and poor) Rich world diseases (cancer, diabetes, cardivascular diseases, ) also affect developing countries and vice-versa (Malaria, TB, ) Treatments and cures are universal (public good)

3 3 International Research Collaborations Priority for the EU - Opportunity for Researchers Access and integration of expertise (people) and knowhow (methodologies and technologies) Networking, Division of Tasks, Pooling of resources (knowledge, infrastructures, investments) Improving health of European citizens and/or increasing competitiveness of European health-related companies Alignment of efforts on common goals with mutual benefits Addressing common global health threats (communicable diseases, (re)emerging epidemics, public health systems in disease-endemic countries) and health challenges (MDGs, non-communicable diseases, global health)

4 The European Research Area (ERA) 27 EU Member States +7 Outermost Regions Guadeloupe, French Guiana, Martinique and Réunion (the four French overseas departments), the Canaries (Spain), and the Azores and Madeira (Portugal) +12 Associated Countries (the EU neighbourhood countries) Albania, Bosnia and Herzegovina, Croatia, Iceland, Israel, Liechtenstein, FYR of Macedonia, Norway, Republic of Montenegro, Serbia, Switzerland, Turkey +FP7 Third Countries Other countries worldwide - can participate in FP7 - some can receive funding (ICPC, incl. BRICS) and others only exceptionally (high-income countries) 4

5 5 International Research Collaborations Health Topics & Funding Schemes Many topics are quite broad / more bottom-up All topics are open for Third Country Participation: An opportunity to involve partners from anywhere in the world US participation is unconditional as in the previous calls Some topics targeting Specific World Regions Some topics calling for Specific International Cooperation Actions (so-called SICAs) Address specific issues that partner countries face or have a global character, on the basis of mutual interest and benefit Programme-Level Cooperation with specific countries alignment & coordination, i.e. agreement of topics + synchronisation of parallel calls + networking/collaboration between funded projects

6 6 International Research Collaborations Minimum requirements & funding For most instruments (CP-IPs, small/medium CP-FPs): Minimum number of participants: 3 from MS/AS Average Size: large CP-IPs 10.7 Mio /17 partners, medium CP-FP Mio / 10 partners, small CP-TP 3.2 Mio / 8 partners Average Third Country Participation: 30% of grants, 8% of participations All topics are open for Third Country Participation But: Specific International Cooperation Actions Minimum number of participants: 2+2 (2 from MS/AS + 2 from ICPCs) Average Size: CP-SICA Mio / 9 partners (5+4) Third Country Participation: up to 9 from third countries! (4 in average) Third Country Participation is not limited to countries of a target region (if any)!

7 7 International Research Collaborations Excellence driven research Some basic rules and guidelines, but: Flexibility The size of consortium (beyond min. 3) The composition of the consortium The duration of the project } is for the applicants to decide (bottom-up) e.g.: a small- or medium-scale Collaborative Project with a 6m ceiling can involve just 3 or 4 partners for only two years with a budget of 4m.

8 8 International Research Collaborations Evaluation and Selection Basic Principles Peer Review Equality, Fairness, Transparency Excellence - only the best will get funded

9 9 Bilateral Programme-level Cooperation EU-NIH Funding Reciprocity «European Union and NIH collaborate» published by SCIENCE on 14 Nov 2008, Vol 322, page

10 10 Multilateral/global Programme-level Cooperations International Research Consortia International Knockout Mouse Consortium (IKMC, 2007) with US, EU, Canada; International Human Microbiome Consortium (IHMC, 2008) with EU, US, Japan, France, Gambia, Australia, Canada (Korea, Ireland); International Cancer Genomics Consortium (ICGC, 2008) with US, EU, DE, UK, FR, ES, IT, Canada, China, India, Japan, Australia, International Human Epigenome Consortium (IHEC, 2010) with EU, US, Australia, possibly Canada, Japan, China, Singapore, South Korea see also the "Human Epigenom Project" at

11 11 International Research Collaborations Some FP7 Facts & Figures All FP7 areas Proposals received (N of participations) All Countries Third Countries (Non-EU, Non-AC) ( ) (14 466) 17% (6%) Grant Agreements (N of participations) (40 729) 958 (2117) 14% (5%) EU funding Mio FP7 HEALTH Proposals received (N of participations) 2315 (21 829) 591 (1464) 26% (7%) Grant Agreements (N of participations) 405 (4241) 123 (327) 30% (8%) EU funding Mio

12 12 International Research Collaborations Third Country Projects All thematic areas

13 13 International Research Collaborations Third Country Participation FP7 COOPERATION in HEALTH Evaluated Short listed

14 International Research Collaborations Opportunities in the next Call (WP2011) Programme-Level Cooperation with: Russia: HTP Proteomics Brazil: Inflammatory and Autoimmune diseases India: Neurodegenerative paediatric diseases India: Cancer from Infectious Agents Brazil: Multilateral cooperation in Public Health Specific International Cooperation Actions: Pop. Genetics on Cardio-Metabolic Disorders Control of Dengue Fever Obesity and/or Diabetes in Specific Populations Reproductive Health and Health Equity Other topics of particular international nature: Zoonotic Viruses Major Epidemic Outbreaks Evolution/transfer of AMDR Determinants of Health Research Capacity Human Epigenomics (IHEC) host aspects of inf.diseases Research Capacity Paediatric Medicines 14

15 15 International Research Collaborations Information & Support Calls for Proposals, Work Programme (Topics) National Contact Points (NCPs) - Information & support for applicants FP6/FP7 projects databases Partner search tools EU health research website

16 16 RTD Career, Training, Mobility Other FP7 opportunities for international cooperation Marie Curie International Incoming Fellowships (MC-IIF) Marie Curie International Outgoing Fellowships (MC-IOF) International Research Staff Exchange Scheme (IRSES) Euraxess - Researchers in Motion, One-stop shop for researchers seeking to move to other countries (Job Portal, Mobility Services, Networks) RTD Capacities Access to Research Infrastructures

17 17 Proposed topics for 2011 WP with an international dimension or focus

18 18 Biotech, tools & technologies 1.1 High-throughput research High-throughput proteomics for human health and disease. Int Funding scheme: collab. project, max 3m, single-stage, one or more proposals. Target Regions: EU, Eastern Europe & Central Asia (EECA), esp Russia Programme-level Cooperation with Russia 1.4 Innovative therapeutic approaches and interventions New therapeutic approaches in chronic inflammatory and autoimmune diseases. Int Funding scheme: collab. project, max 3m, single-stage, one or more proposals Programme-level Cooperation with Brazil

19 Translating research for health large-scale data-gathering: High impact initiative on the human epigenome. Funding scheme: collab. project, max 30m, single-stage, max one proposal. Cooperation with Int. Human Epigenomics Consortium (IHEC) Large-scale genomics approaches to identify host determinants of infectious diseases. Funding scheme: collab. project, max 12m, single-stage, max one proposal Population genetic studies on cardio-metabolic disorders in EU/AC and EECA populations. Int Funding scheme: Specific International Cooperation Action (SICA), collab. project, max 6m, single-stage, max one proposal. Target Regions: EU/AC, Eastern European & Central Asian Countries (EECA) 19

20 Translating research for health Research on the Brain and related diseases, human development and ageing: Creating clinical and molecular tools for experimental therapy of paediatric neurodegenerative disorders causing childhood dementia in Europe and India. Funding scheme: collab. project, max 3m, single-stage, one or more proposals. Target Regions: EU & India Programme-level cooperation with India Anti-microbial drug resistance Int Multi-disciplinary research on the evolution and transfer of antibiotic resistance. Funding scheme: collab. project, max 12m, single-stage, max one proposal. 20

21 Translating research for health Potentially new and re-emerging epidemics Identification of factors promoting the emergence of pathogens with human pandemic potential from pathogens with a zoonotic background and related prevention strategies. Funding scheme: collab. project, max 12m, two-stage, max one proposal Comprehensive control of Dengue fever under changing climatic conditions. Int Funding scheme: SICA - collab. project, max 6m, single-stage, one or more proposals Target regions: Latin America & Asia Development of an evidence-based behavioural and communication package to respond to major epidemic outbreaks. Funding scheme: collab. project, max 2m, 2-stage, one or more proposals. 21

22 22 Translating research for health Cancer Epidemiology and aetiology of infection-related cancers Funding scheme: collab. project, max 3m, 1-stage, one or more proposals. Programme-level cooperation with India Int Diabetes and obesity Genetic and environmental factors in obesity and/or diabetes in specific populations. Int Funding scheme: SICA collab. project, max 3m, 2-stage, one or more proposals. Target regions: Africa, Asia, Latin America, Mediterranean countries Programme-level cooperation with Mexico, Australia, New Zealand

23 23 Translating research for health HIV/AIDS, malaria and tuberculosis Closed in Neglected infectious diseases Closed in 2011

24 24 Optimising delivery of healthcare 3.3 Health promotion Developing methodologies to reduce inequities in the determinants of health. Funding scheme: collab. project, max 3m, 2-stage, one or more proposals. 3.4 International public health & health systems Development and assessment of comprehensive and integrated interventions and programmes to improve reproductive health and health equity. Funding scheme: SICA - collab. project, max 3m, single-stage, one or more proposals Target Region: ICPC (low- & middle-income countries) Int

25 Optimising delivery of healthcare 3.4 International public health & health systems Building sustainable capacity for research for health and its social determinants in low and & middle income countries. Funding scheme: CA, max 2m, single-stage, one or more proposals. Target Region: ICPC (low- & middle-income countries) Int Multilateral cooperation between Europe, Africa and Latin America on public health and health services research. Funding scheme: CA, max 2m, single-stage, max one proposal. Target Regions: EU, Africa, Brazil Programme-level cooperation with Brazil Int 25

26 26 Actions across the Health theme 4.1 Coordination and support actions across the theme Linking EU and Latin American policy-making institutions in the field of health research. Funding scheme: CA, max 2m, single-stage, max one proposal. Target Region: EU & Latin America Int 4.2 Responding to EU Policy needs Investigator-driven clinical trials on off-patent medicines for children. CT Funding scheme: collab. project, max 6m, single-stage, one or more proposals.