3 rd Nano-Science Center Winter School 29/1 4/2 2008, Maria Alm, Austria

Transcription

1 3 rd Nano-Science Center Winter School 29/1 4/2 2008, Maria Alm, Austria Workshop Program: Descriptions: Center for Molecular Movies: The structure of materials is an important key to understanding the relationship between synthesis and processing of the materials and their functionalities. However, the functionality of materials often involve that they - at least briefly - change the local arrangement of their constituent atoms and molecules, and hence their structure. In this workshop we will review the present status of the techniques and methods for investigating transient structures of materials in the Centre, as well as discuss new ideas for photo- and electrically excitable materials. We will have tutorials on predicting Structure-Property relationships, Photochemistry, Crystallography, and methods for data analysis followed by discussion of their applications. In the last part of the workshop, we will form working groups with the goal to provide the springboards for the next generation of research projects in. SINGLE: This purpose of this workshop is to start up the EU collaborative project SINGLE; a study of the single molecules and single molecule/electrode interfaces. The workshop will be attended by all the collaborators from the SINGLE project, giving a broad scope on a single topic. In the workshop practical issues will touched briefly, but the main focus is the science of single molecules in two or three terminal devices. NanoWires: The workshop will cover two main projects resulting from strong collaborations between the BioNano laboratory and the group on Nanoscale Quantum Electronics: (1) Interfacing nanorods and mammalian cells for monitoring cellular events and (2) development of label free biosensors using Nanowire-Field Effect Transistors (Bio-FET). Single Enzymes: Single enzymes experiments are the only way to precisely quantify the catalytic behavior of the enzymes. Aspects such as time dependent activity fluctuations, otherwise masked in ensemble average measurements, have been successfully resolved by these experiments. In this session a variety of methods utilized for measuring the real time kinetics of single hydrolytic enzymes are discussed. As demonstrated enzymes can adopt a variety of inter-converting conformations each one of them exhibiting different activity. The effect of the microenvironment on their oscillating behavior is in depth studied and models are proposed successfully interpreting the results.

2 Program: SINGLE Chair: T. Bjørnholm 9:00 10:30 Project overview: Thomas Bjørnholm Scientific challenges Poul Petersen Administrative issues Wednesday 30/1-08 9:00 10:30 Scientific Outlook : Results & Outlook Morten Christensen Structural dynamics in solution Henrik Lemke Structural dynamics in thin films of organic semiconducters 11:00 12:30 Jerome Cornill/Victor Geskin Presentation from MONS 11:00 12:30 Instrumentation and methods Dmitry Khakhulin Laser driven X-ray Diode Simon O. Mariager Femtoslicing sources Thomas N. Nielsen Fast detectors and electrical excitable systems Beamtime planning/application

3 Thursday 31/1-08 SINGLE Chair: T. Bjørnholm 9:00 10:30 Herre van der Zant/Edgar Osorio Presentation from Delft 11:00 12:00 Heike Riel Presentation from IBM 9:00 10:30 Tutorial: Jerome Cornill The relationship between structure and charge transport properties of materials Chair: M. Christensen 11:00 12:30 Tutorial Kristine Kilså Photophysics & photochemistry

4 Friday 1/2-08 SINGLE Chair: T. Bjørnholm 9:00 9:30 Presentation from Chalmers Andrey Danilov Progress on SET experiments at Chalmers 9:30 9:50 Per Hedegaard C60 quantum switch 9:50 10:10 Gören Wendin Functional molecular electronic devices - what are relevant problems for theory? 10:10 10:25 Thomas Löfwander Graphene 10:25 10:40 Zeljko Crljen Molecular wires in nanogaps 11:00 11:35 Presentation from Cph Morgens Brøndsted/Kristine Kilså Design, synthesis and molecular properties of new test molecules 11:35 11:50 Kasper Moth Self-assembly of gaps using gold nano rods 11:50 12:10 Kristen Kaasbjerg Hückel calculations of OPVs in nano gaps 12:10 12:30 Jens Paaske Modeling renormalization effects in single molecule and CNT transistors Chair: D. Khakhulin 9:00 9:45 Emil Makovicky Introduction to experimental X-ray crystallography Chair: Henrik Lemke 9:45 10:10 Fredrik Westerlund Structure and optical properties of fluorescent thin films 10:30 11:30 Thomas Just Sørensen/Klaus Bechgaard Relation between structure and optical properties of molecules & Novel systems of interest to time-resolved X-ray scattering 11:30 12:00 Thomas Bjørnholm 12:00 12:30 Formation of 2-4 project groups to explore the best ideas from the last two days Project group discussion

5 Saturday 2/2-08 Single Enzymes Chair: N. Hatzakis 9:00 9:20 Nikos Hatzakis: Single Enzymes Studies on Lipase Activity 9:40 10:20 Li Wei Effects of Environment on Conformational Fluctuations of Lipases at a single molecule level 10:20 10:40 Coffee break 10:40 11:30 Thomas Bjørnholm Activity Studies of Single Phospholipase Molecules 11:30 12:10 Andreas Kunding Enzyme Activity Studies in Single Vesicles Chair: K. Haldrup 9:00 10:30 Per Hedegaard Data analysis and parameter determination 10:55 11:20 Kristoffer Haldrup "Analysis of time-resolved solution scattering Data" 11:20 11:45 Andreas Kring "MD simulations" 11:45-12:30 The project groups discuss and each group write a few bullets on their present ideas. Project group discussion

6 Sunday 3/2-08 NanoWires Chair: K. Martinez 9:00 9:40 Karen Martinez Using Nanowires for Sensing of Biological Events 9:40 10:10 Brian Skov Sørensen About the Physical Platform of the BioFET (an in-house status) 10:10 10:30 Coffee break Chair: R. Feidenhans l 9:00 10:30 Presentation of results from the project groups 11:00 12:30 Discussion of the results plans for the future Project group discussion 10:30 11:00 Lars Iversen How to design recognition motifs for Bio-FET 11:00 11:30 Yi-Chi Liu Functionalization of Silicon Nanowires for Scientific Protein Immobilization 11:30 12:00 Nathalie Rieben Development of Suitable Recognition Motifs for Glutamate Sensing