Impact from Excellence

Transcription

1 III-V FAB Impact from Excellence Aligning our research with the Medtech Industry s requirements for Bio- Photonics and Photonics Integration. Ray Burke Program Manager ICT for Health Tyndall National Institute Cork, Ireland

2 Ireland s National Institute for ICT Research Development and Innovation

3 ICT for Health at Tyndall Tyndall will deliver new opportunities for Ireland economic growth creating impact from excellent research, systems development and graduate training, delivering disruptive ICT solutions & highly trained people to meet challenges in the HEALTH, Medical Devices and Life Sciences sector. Impact from Excellence in ICT for Health

4 ESTHER Emerging and Strategic Technologies for Healthcare

5 Primary focus on Scientific Discovery delivering science, publications & patents Centre and Industry Sector Matrix Deliver Commercial Output Commercial PIs (Progr. Managers) & Researchers Multidisciplinary Solutions for industry Photonics Micro/Nano Systems Health Communications Energy Secure, Agriculture, Food & Environment Expertise, know-how, Background IP Foreground IP Technology Platforms & Solutions Industry Collaboration Demos Licenses Start-ups

6 ICT for Health at Tyndall Core Enabling Technologies Smart Systems Core Enabling Technologies Micro & Nano Technologies Electronics & Photonics

7 ICT for Health at Tyndall Research & Technology platforms Molecular modelling Electronic integration Research & Technology platforms Advanced Sensors Lab on chip systems Smart Systems Core Enabling Technologies Advanced Processing Wireless inertial sensing Micro & Nano Technologies Electronics & Photonics Micro Power Photonic systems Photonic devices Photonic packages

8 ICT for Health at Tyndall Diagnostics Applications Molecular modelling Electronic integration Research & Technology platforms Advanced Sensors Surgical Innovation & TEL Lab on chip systems Smart Systems Advanced Processing Connected Health Core Enabling Technologies Wireless intertial sensing Micro & Nano Technology Electronics & Photonics Micro Power Cardio- Neuro Interfacing Photonic systems Photonic packages Photonic devices Therapeutic Systems

9 Tyndall ICT4 Health - leading an ABC Ecosystem We Collaborate with global medtech companies, world leading clinicians and leading scientists. Tyndall & Academic partners ABC Ecosystem Academic, Business, Clinical) Clinical Partners Clinicians & Patients Business Partners

10 Photonics expertise/capabilities Basic Phenomena Materials Epitaxy Devices Integration Systems Photonics Theory Electronic structure and properties, III-V materials & devices Quantum Information Single photon sources, quantum key distribution systems Bio-Photonics Light and tissue interactions III-V & III-Nitride materials Semiconductor optoelectronic device structures, quantum well, wires, dots & nanostructured epitaxy Device Fabrication Novel photonics structures Visible, near-ir & UV lasers, (micro)leds, modulators & detectors Device Design & Test Optical design to device dynamics, laser physics, power scaling, ultrafast pulses Microelectronics Driver and receiver integrated circuits Photonic Integration High-speed integrated optoelectronic transceivers Packaging Packaging & hybrid integration Silicon Photonics Micro-transfer printing, integrated electronic and photonic circuits Optoelectronic Systems Optical fibre communications & optical interconnects Bio-photonic Systems Point of care diagnostics, smart surgical instruments & wearable devices

11 11 World-Class Facilities atoms to systems approach

12 Basic Phenomena Photonics - Team Materials Devices Integration Systems Largest photonics research activity in Ireland 16 PIs + teams (150 people in total, 50 PhDs) Internationally competitive, connected and visible Gunning Ossieur Zhao Photonic Integration High speed integrated optoelectronic devices Townsend Photonic Systems Fibre communications High speed microelectronics design Photonic Packaging Packaging & hybrid integration Significant PI industry experience: Lead/host for SFI/industryfunded Irish Photonics Integration Centre (IPIC) Bio photonics Optical Detectors APDs & IC integration Medical devices and bio-imaging Peters Corbett III-V Materials & Devices Visible & near-ir lasers & LEDs O Brien Huyet Device Dynamics CAPPA group: Laser dynamics, material studies & optical design Morrison Hegarty McInerney Andersson-Engels Laser Physics Lasers & devices Epitaxy & Physics of Nanostructures III-Nitride Materials UV & visible sources Pelucchi III-V Epitaxy, quantum dots & quantum optics Parbrook Photonics Theory Electronic structure and properties of III-V materials & devices Schultz O Reilly

13 Expanding Biophotonics and Medical Application Expertise International search identified Prof. Stefan Andersson-Engels, Director of Medical Laser Centre at Lund University, Sweden as leading candidate Main fields of interest Laser spectroscopy and imaging for medical diagnostics, Photodynamic therapy, Tissue Optics Academic leader and active entrepreneur >400 publications, H-Index of 52, 3 biomedical startup companies Extensive experience of working with clinicians Current status SFI Professorship application (value 5M) funded Started full-time at Tyndall 1 st September 13

14 Tissue Imaging Various techniques are today used in medical imaging and interactions. Optics provides unique molecular contrast opportunities in tissues. There is a great need for improved tools for interacting with deep tissue regions. Photo-acoustics is a technique starting to enter the preclinical and clinical use.

15 Ultrasound Optical Tomography Grand challenge: can we see through the body using light? 1

16 Irish Photonic Integration Centre Academic institutions Together with 20 industry partners 30 Million funding (30% industry, 70% SFI) for initial 6 years Focus areas: integrated systems for ICT and Medtech Monolithic Integration Hybrid Integration

17 Principal Investigators Full photonics and electronics value chain 60 people directly funded, 150 people in wider teams Prof. Stefan Andersson-Engels (formerly Lund University) 5M programme in biophotonics 17

18 International Recognition Brian Corbett receiving 2013 Intel Outstanding Researcher Award for his work on light sources for computer interconnects Eoin O Reilly receiving the 2014 Rank Prize award for his pioneering work on strainedlayer semiconductor laser structures

19 Industry Partner Expansion IPIC Start Pipeline of further target companies being developed with support from IDA and Tyndall Business Development Team

20 Research Snapshots III-V Materials & Theory Optical Interconnects and Microelectronics Devices including Transfer Printed Lasers III-V PICs nm Nanostructure enhanced fluorescence for biosensors 200nm Photonics Packaging 0.00 nm Super Channel Systems and PONs New Lasers for OCT O 2 Sensing in tissue

21 Chip on tip Challange

22 Documentation DHF & Compliance URS User Requirements Specification TRS Test Requirement Specification SRS System Requirement Specification FT Functional Testing DOS Design Output Specification DVT Design Verification Testing DFEMA Design Failure Mode and Effects Analysis Implementation

23 ACTIONS Team Team ACTIONS START Implementation Example Flow Diagram Define User Case & URS Market Analysis data Commercial Strategy Detailed Business Plan Technology Licences Clinical Requirements Clinician Lead, Industry Lead, commercial input from team and EMR suppliers on technology, market etc. Design the product Sensor Integration Hardware Software Communications Alpha Prototypes Design for manufacture Tyndall, Technion, Marturion Industry, EMR suppliers & Advisory Board Market Analysis & Technology Phase Month 1-14 Mechanical Design Functional Prototype Build Design verification testing Verify Usability Device testing System level interface Tyndall, Technion, Marturion Industry, EMR suppliers & Advisory Board Ethical Approval Clinical Testing Regulatory Submissions Approvals testing Design Validation Production Process Process validation Supply Chain Process Sample volumes Marketing Commercialisation Marketing Distributor Development Market Development Product Roadmap Industry CMO, Technical Team Partner Hospitals Partner Clinicians EMR suppliers & Advisory Board Industry, Technical team, Partner Hospitals,Distribution and manufacturing Network EMR suppliers & Advisory Board Industry, Partner Hospitals, distribution and manufacturing Network EMR suppliers & Advisory Board Regulatory and Commercialisation Phase Month Commercialisation Month 30-36

24 Some Suggestions Working with medtech companies or interested in translating research to medtech sector, then we need to be strategic. They will want a system level approach or understanding. Device classification. Propose and build technology platforms. Third parties & Supply Chain. Starting point remember the ABC Model. Understand the clinical procedures ask for a target or typical procedure. Try and understand commercial application early. Regulatory Path, in-vivo testing, first in man & Clinical. Contract Research Agreement, NDA, get pro-forma versions to the Industry partner early these can take a year to conclude, insurance and liabilities. Researcher in Residence program.

25 Thank you for your attention