NORMAN Network of reference laboratories for monitoring of emerging substances

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1 WFD Lille 2007 NORMAN Network of reference laboratories for monitoring of emerging substances Jaroslav Slobodník, Valeria Dulio Environmental Institute Emerging environmental substances Substances not included in routine monitoring programmes Present in environment Candidate for future regulations Research on effects/occurrence Abundance 2e+07 TIC: MSBA.D TIC: NI014.D (*) 1.8e e e e+07 1e EtAc/USE extract IS of 1 g NI 014 sediment IS blank Time--> 1

2 Emerging environmental substances Algal toxins Anticorrosives Antifoaming agents Antifouling compounds Antioxidants Biocides Bio-terrorism/ sabotage agents Complexing agents Detergents Disinfection by-products (drinking water) Flame retardants Fragrances Gasoline additives Industrial solvents Nanoparticles Perfluoroalkylated substances and their TPs Personal care products Pesticides Pharmaceuticals Trace metals and their compounds Wood preservatives Other Emerging substances Frequently Asked Questions Should we eventually monitor the whole universe of chemicals and their mixtures? If not all which ones? Are the substances we find toxic? Should some of the substances be monitored on a regular basis? If so, at which concentration levels? Is there enough scientific evidence to make decisions implying high costs? Can we trust the data? Who else is dealing with the substances we found? 2

3 NORMAN - FP6 - Coordination Action - Priority 6.3 Coordination: INERIS Start date: 1/9/2005 Duration: 3 years 17 partners NORMAN objective Creation of a permanent network among national reference laboratories and research centres Collaboration with the parties involved (industry, standardisation bodies, NGOs, etc.) 3

4 NORMAN goals More rapid and wide-scope exchange of data and information on emerging substances Better data quality and comparability via validation and harmonisation of common measurement methods and monitoring tools More transparent information: information, not only data Independent and competent forum for the technical/scientific debate on issues related to emerging substances NORMAN today Scientific watch and information exchange Literature research - databases and newsletter Workshops - 4 events NORMAN Contact Points - info gathering Collection/evaluation of data Three web-based databases on emerging substances (EMPO-MAP, -DAT, -MASS) Validation and harmonisation of methods Common European protocol for method validation 4

5 Effects: Navigating NORMAN databases Occurrence: -list of metadata -what this data represent? bioassays, biomarkers NORMAN Contract FP6 Priority 6.3 Mass spectra + num info -for not yet identified substances Substance Institutes: -X. Bbb -Y. Bcc -Z. Bdd NORMAN Contract FP6 Priority 6.3 Experts: -A. Bbb -B. Bcc -C. Bdd Projects: - Modelkey - PERFORCE - Sednet Institute Y - Projects - NORMAN - KNAPPE - PERFORCE NORMAN Contract FP6 Priority 6.3 EMPOMAP: available on the NORMAN website you are invited to register as an expert and/or organisation + projects 5

6 NORMAN today Scientific watch and information exchange Literature research - databases and newsletter Workshops - 4 events NORMAN Contact Points - info gathering Collection/evaluation of data Three web-based databases on emerging substances (EMPO-MAP, -DAT, -MASS) Validation and harmonisation of methods Common European protocol for method validation Common European protocol for method validation three levels of validation Research method, incomplete internal validation, probably not applicable for organism, compartment or matrices of interest Method applicable by research labs (complete internal validation) Validation Protocol V1 Method applicable by expert labs (transferable to another lab with sufficient expertise) Method applicable by routine labs (comprehensive external validation) Validation Protocol V2 Validation Protocol V3 Method validation & maturity status 6

7 Procedure for development & implementation VALIDATION: Development of protocols Inter-laboratory studies (TEST PHASE) Oestrogens in wastewaters Non-steroidal anti-inflammatory drugs in waters DecaBDE in dust VALIDATION: New Work Item proposals Improvement & at CEN for development Implementation of guidelines or CEN TR NORMAN tomorrow? A self-sustainable permanent network 7

8 tools QAwatch ¾Provide Info sharing Scientific Forum for technical debates priority of high substances ¾Identify ¾ Databases Scientific watch bulletin ¾ Scientific watch ¾ Scientific watch bulletin ¾Expert group meetings and status of methods of ¾Check availability RTD with ¾ Exchange ¾List of priority topics for ¾List of priority topics for ¾ Workshops/conferences research validation projects research ¾Position papers ¾ Meetings/training for or experts, PT providers ¾Bring together ¾Position papers sharing routine labs studies ofinfo organisation bodies for rapid other QA/QC ¾ Databases ¾Tools for methods for method validation ¾ Exchange with validation studies RTD projects at various levels validation of information ¾Guidance onexchange ¾Expert group meetings needs of the customers according to the workshops/conferences ¾ Meetings/training for routine labs Network of reference laboratories Reducing time from discovery of an emerging pollutant to the production of reliable results (chemical and biological) Scientific basis for decision-making Scientific watch to advise authorities and anticipate research needs Independent and competent forum for the technical/scientific debate on issues related to emerging substances Ensuring the synergy among the various research programmes dealing with emerging pollutants 8

9 Next NORMAN Workshop New tools for bio-monitoring of emerging pollutants Autumn 2007, Amsterdam 9