Life Sciences in the Czech Republic

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1 Life Sciences in the Czech Republic

2 Czech Life Sciences atat aa Glance Czech Life Sciences Glance academic community basebase withwith a strong commitment to partnering withwith + World-class academic community a strong commitment to partnering + World-class industrial R&D,R&D, supply chain + Established industrial supply chain + Established patent harmonious withwith thatthat of the + Regulatory patent harmonious of EU the EU + Regulatory presence of large international pharmaceutical companies participating in programmes + Strong presence of large international pharmaceutical companies participating in programmes + Strong conducting operations conducting operations translational supported by close ties ties between universities, institutions, + Clinical translational supported by close between universities, institutions, + Clinical the public healthcare system the public healthcare system of university graduates -specific staffstaff at competitive prices + Availability of university graduates -specific at competitive prices + Availability business incentives for both R&DR&D + Supportive business incentives for both + Supportive Over 20% of of allall university students study natural sciences Over 20% university students study natural sciences forfor upup to to 45% of of 45% 70% of of forfor R&D upup to to 70% R&D Timeline Timeline Jan Jan Evangelista Purkyně Evangelista Purkyně formulates the cell theory formulates the cell theory Neurologist Sigmund Freud Neurologist Sigmund Freud pioneers the field pioneers the field of psychoanalysis of psychoanalysis Charles University Prague Charles University Prague Gregor Johann Mendel Gregor Johann Mendel the oldest home for study the oldest home for study the principal the principal of naturall science of naturall science lawslaws of heredity of heredity

3 Companies and Research Centres Companies and Research Centres Poland Poland Slovakia Slovakia Austria Austria Jaroslav Heyrovský Jaroslav Heyrovský FDAFDA approves the anti-aids approves the anti-aids receives the Nobel PrizePrize receives the Nobel hepatitis B drugs developed hepatitis B drugs developed for chemistry for chemistry by Prof. Antonín HolýHolý by Prof. Antonín Jan Jan Jánský Jánský OttoOtto Wichterle produces Wichterle produces the four blood types the four blood types the first soft soft gel contact lenses the first gel contact lenses

4 Investment Success Stories John F. Milligan John R. Westby Angelo Cornelissen President and CEO, Gilead Sciences Associate Vice President, CFO, Synthon BV Global Support Functions IT at MSD Gilead Sciences decided in 2006 to establish Prague was chosen from several other considered Synthon has found in the Czech Republic in Prague its only R&D centre outside the United locations mainly because of accessibility to human high-quality expertise in organic, analytical States with the Institute of Organic Chemistry resources from the field of science and IT and well and pharmaceutical chemistry, which provides and Biochemistry of the Czech Academy of functioning education system that trains those an ideal for development of our Sciences. We have done so because of Dr. specialists. The MSD IT hub offers opportunities and activities here. Antonín Holý and his team have shown such for career development not just for a wide range productivity and such impressive scientific of IT experts and data analysts, but also for new leadership over the years. graduates who could start to work in a global pharmaceutical company that is a leader in the novel application of progressive technology to the field of healthcare. Life Sciences at Czech Universities Main Universities in the Czech Republic Students: 53,175 Graduates: 10,493 Charles University in Prague Students: 18,065 Graduates: 2,830 University of South Bohemia in Ceske Budejovice Students: 2,642 Graduates: 624 Palacký University, Olomouc Students: 4,566 Graduates: 836 University of Chemistry and Technology, Prague Students: 3,514 Graduates: 786 Masaryk University in Brno Students: 7,036 Graduates: 1,365 University of Ostrava Students: 3,231 Graduates: 498 University of Veterinary and Pharmaceutical Sciences Brno Students: 2,725 Graduates: 460 University of Pardubice Students: 2,132 Graduates: 510 Source: Ministry of Education, Youth and Sport, 2017

5 Selected Research Institutes, Academy of Sciences of the Czech Republic Institute Plan Animal Environ. Enzyme Microbial /Cell Human/Veter. diagn./therap. Basic Institute of Biophysics Institute of nology Institute of Experimental Botany Institute of Experimental Medicine Institute of Microbiology Institute of Molecular Genetics Institute of Organic Chemistry and Biochemistry Institute of Parasitology Biology Centre of the AS CR Experienced -specific staff The chart shows the breakdown of Experienced -specific staff. Labour Availability and Quality The chart shows the breakdown of Labour Availability and Quality. UK USA France Switzerland Sweden Japan South Korea Czech Republic Switzerland Sweden UK France Japan South Korea Czech Republic USA Employment in (% of total employment) Researchers in Research and Development Availability of scientists and engineers Research and training services availability Experienced -specific staff Flexibility of labour regulations Overall size of labour market Non-experienced staff Skills, attitudes and productivity Tightness and competition for labour Source: fdi Benchmark from the Financial Times Ltd 2017 Source: fdi Benchmark from the Financial Times Ltd 2017

6 CzechInvest Headquarters and Foreign Offices: CzechInvest Headquarters and Foreign Offices: Republic Prague CzechCzech Republic Prague Düsseldorf Düsseldorf Seoul SouthSouth KoreaKorea Seoul East Coast New York USA USA East Coast New York fdi@czechinvest.org fdi@czechinvest.org seoul@czechinvest.org germany@czechinvest.org seoul@czechinvest.org germany@czechinvest.org newyork@czechinvest.org newyork@czechinvest.org Stepanska 00 Prague 2 Stepanska 15, 12015, Prague 2 Tokyo JapanJapan Tokyo Scandinavia Scandinavia West Coast San Francisco USA USA West Coast San Francisco tokyo@czechinvest.org tokyo@czechinvest.org california@czechinvest.org scandinavia@czechinvest.org california@czechinvest.org scandinavia@czechinvest.org Shanghai ChinaChina Shanghai UKIreland and Ireland London UK and London china@czechinvest.org china@czechinvest.org Ukraine Ukraine Kiev Kiev london@czechinvest.org london@czechinvest.org in 2017in 2017 Canada Toronto Canada Toronto in 2017in 2017