Advanced Membrane Separation & Surface Technologies

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1 ACADEMIC EXPERTISE FOR BUSINESS (A4B) Advanced Membrane Separation & Surface Technologies Knowledge Transfer Centre

2 Centre Aims Deliver specific knowledge transfer activities for the uptake of membrane and surface technologies in Wales. The Centre will provide enterprises with; Knowledge of membrane technologies and commercial benefits Access to equipment, know-how and technology

3 The Market Target Sectors Process Engineering Environment Food Biomedical/Health Biotechnology

4 The Technology Advanced Membrane Separation & Surface Technologies Project Themes 1. Selective Separation and Product Recovery 2. Advanced Surface and Fluid Characterisation 3. Novel Membrane and Structure Fabrication

5 KTC Collaboration Pulse Medical Technologies Ambulatory Magneto-Enhancement of Transdermal High Yield Silver Therapy (AMETHYST- FP7 820,338 ) 8 European SME s and Swansea University Swansea Team 4 Post Doctoral Researchers CNH Academic Staff PULSE MEDICAL TECHNOLOGIES Exploded view of the AMETHYST electromagnetic component Established wound and biofilm models to test the printed electronic delivery of the electromagnetic pulse.

6 KTC Collaboration AlgiPharm is a biopharmaceutical company with primary focus on respiratory diseases, wound healing and other conditions caused by microbial infections and biofilms. A long term collaboration with Cardiff Dental School has led to an exciting collaborative project. AFM image (10mm 2 ) of a microbial biofilm Rheometer used to study the mechanical properties of biological gels such as blood, collagen and sputum a Norwegian pharmeceutical company using rheometry and AFM. control of mechanical properties of biological materials. to develop techniques to disrupt biofilms that form in the lungs of cystic fibrosis patients. measuring mechanical properties of mucus, sputum and bacterial biofilms.

7 KTC Collaboration Haemair Ltd Development of a Blood/Air Mass Exchanger to be Used as a Prosthetic Lung Established long-term collaboration. Haemorheology Laboratory in the Morriston Hospital is jointly supported by the EPSRC and the National Health Service. Measurement of blood rheology and clotting. Investigation of novel membrane structure and surface modification methods for hemocompatibility 1. The device must achieve design mass transfer rates for oxygen and carbon dioxide. 2. Materials of design must be biocompatible and hemocompatible.

8 KTC Activities Selective Separation/Product Recovery Microbial fermentation for enzyme production Selective Separation of protein hydrolysates Concentration of plant extracts Advanced Surface/Fluid Characterisation Assessment of novel filter media and membranes for process fluid separation Application of AFM in processing environment Novel Membrane & Structure Fabrication Investigation of novel membrane structure for hemocompatibility Production of biodegradable porous scaffolds for tissue engineering

9 Contact Details Dr Greg Coss Industrial Liaison Officer Advanced Membrane Separation and Surface Technologies KTC School of Engineering Swansea University Swansea. SA2 8PP Tel: