Talk with the editors of THE JOURNAL OF BIOLOGICAL CHEMISTRY

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1 Talk with the editors of THE JOURNAL OF BIOLOGICAL CHEMISTRY

2 Part 1: What s new at the JBC?

3 Mission Statement The Journal of Biological Chemistry encourages the submission of manuscripts based on original research that are judged to make a novel and important contribution to understanding the molecular and cellular basis of biological processes.

4 Affinity Groups (Journal within a Journal) Helping scientists connect

5 Find subjects that interest you Minisites" at - pages that create "homes" for journal sections: Information of interest to specific affinity groups Theme issues focused on specific scientific areas Minireview series Reflections and Classics

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7 Board Search New site will highlight affinity groups You can find the best editors for your paper Find the best editors for your paper

8 Your work will be seen! Your paper will be published the day it s accepted! Papers in Press available to all Highlighted on the JBC homepage

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10 An enriched mobile experience JBC iphone app More than 1,000 downloads in first months of launch iphone-optimized content Mobile site Works on different mobile devices (Android phones, iphones) No app download needed (located in browser) Simplified interface Users are automatically redirected to this site when they open in their mobile browser

11 Questions/Comments?

12 Part 2: Resources for Authors Page/Color Charges Submission Fee Author s Choice Option Guidelines for Editorial Decisions What You Need to Submit

13 On JBC.org: Resources for Authors The Online Submission Instructions explain our manuscript-tracking system The Instructions to Authors explain JBC's manuscript style and format rules The Guidelines for Preparing Digital Images for Submission covers sizing, color, fonts, resolution, etc. Rapid Inspector imagechecking software is also available.

14 On JBC.org: Resources for Authors The JBC Editorial Policies page provides an overview of our publication policies The JBC and PubMed page tells how/when content is deposited in the repository The Language Assistance is for authors who are not native English speakers and desire help with grammar, vocabulary, and style The Copyright Permission page is for authors who wish to reuse JBC material

15 Page Charges There is a per page charge for all published manuscripts. It is $80 per page for the first nine pages and $160 starting with the 10th page. All page and color fees must be paid by the authors. ASBMB does not accept requests for page or ASBMB does not accept requests for page or color waivers. In extreme situations for developing economies, an exemption may be considered for page charges if requested at the time of submission.

16 Color Charges We encourage authors to use color figures when they will enhance the presentation of the data. The cost is $100 for each illustration containing color. When usingthe electronic submission system, any figure submitted in color will be reviewed and processed with the understanding that the figure will be published in color.

17 No submission fee: If you are using the system for the first time, you must create an account. To submit, enter the Author Area and click on Submit a New Manuscript. You will be presented with a series of fields for entering your manuscript metadata and will then be asked to upload your manuscript file and any image files not embedded within your manuscript file. Supplemental data and images can also be uploaded. The system will convert your files to a single PDF file for reviewing purposes. You will receive an message when conversion of your manuscript is completed, and you can then visit the Ready to Proof queue in the author area to approve your submission.

18 Author s Choice Publishing Option This method of publishing is not mandatory and carries a fee in addition to the standard page and color charges. WHY? Immediate release on the publisher's site and PubMed Central of your final version of your manuscript. If you are funded by Howard Hughes Medical Institute and Wellcome Trust, this method of publishing is highly recommended. FEES $1,500 for ASBMB members $2,000 for nonmembers If the Author Choice option is selected after publication, an additional $250 fee applies.

19 READ THE JBC EDITORIAL GUIDELINES!

20 Guidelines for Editorial Decisions Cell cycle and apoptosis Manuscripts that report significant advances in understanding the cell cycle or apoptosis. Appropriate FACS analysis procedures will include multiple parameters and/or time points to establish biological states. Computational biochemistry and biomolecular networks Manuscripts describing computational analyses in structural biology, enzyme kinetics, systems biology and bioinformatics that provide significant new insights into a molecular or cellular process or its regulation. Enzymology Manuscripts that provide new insight into catalytic mechanisms of enzymes. Manuscripts that report three dimensional structures of enzymes, including new folds, and that provide insight into understanding the functions of enzymes. Manuscripts that describe the purification and characterization of novel enzymes or proteins that have not been described previously in other tissues or organisms.

21 Guidelines for Editorial Decisions Experimental uncertainty and reproducibility Results should be accompanied by explicit analyses of experimental uncertainty and reproducibility. Acceptable analyses of experimental uncertainty of numerical data include the standard deviation, the standard error, or the mean and range of values obtained from replicate experiments, as appropriate. Bar graphs and scatter plots (X,Y plots) should include error bars, and the meaning of the error bars should be defined in the text. Plots that include lines that represent fits of experimental data must be accompanied by the equation used to calculate the fit, the values of the fit parameters, and statistics that characterize the quality of the fit. Functional genomic, metabolomic and proteomic analysis Manuscripts that use genome, metabolome, or proteome scale functional analysis by differential display, microarray, mass spectrometry, or other methods to provide novel insight into a biological process or its regulation.

22 Guidelines for Editorial Decisions Glycobiology Manuscripts that describe the structure, function and metabolism of novel oligosaccharides and glycoconjugates. Imaging studies Manuscripts that report the elucidation of biological processes using imaging experiments that include appropriate analyses of experimental reproducibility and uncertainty. Macromolecular interactions Manuscripts that describe biochemical analyses of interactions between macromolecules or between macromolecules and small ligands (e.g., biophysical methods such as NMR, hydrodynamics, or isothermal calorimetry, or results of two hybrid screens, coimmunoprecipitation, gel mobility shift, or related assays) and provide information about the functional consequences of the interactions as they occur between partners expressed from the endogenous genes in relevant cell lines or tissues.

23 Guidelines for Editorial Decisions Methodology and techniques Manuscripts that report the development of a new technique or methodology and apply it to obtain a novel and significant insight into a biological process. Molecular bases of disease Manuscripts that contribute novel and significant insights into biochemical processes that form the molecular bases of disease. Mutational analysis of proteins Manuscripts that report that mutation of a protein alters its function and provide clear evidence regarding the process by which the function is altered.

24 Guidelines for Editorial Decisions Neurological biology Manuscripts that provide significant insight into the molecular bases of neurological disorders, biochemical basis of neurophysiology, electrophysiology, neurodevelopment, synapse formation, addiction, behavior, or psychological/psychiatric disorders, with the major emphasis of the study being on the molecular or cellular aspects rather than the whole organism or whole system response. Manuscripts that provide novel molecular insights into the genesis, identification, differentiation, or maintenance of neural progenitor cells. Post translational modification Manuscripts that describe modification of a protein by a novel process or by a well established process such as glycosylation, phosphorylation, fatty acylation, or prenylation and demonstrate the biological or biochemical significance of the modification or provide novel insight into the modification process. Regulation of metabolism and gene expression Manuscripts that provide significant insight into the underlying biochemical process of the regulation of metabolism and gene expression.

25 Guidelines for Editorial Decisions RNAi Manuscripts that use RNA interference (RNAi) to probe biological processes should include appropriate controls as described in Nature Cell Biology 5, (2003). Such controls may include use of sirnas with one or two nucleotide changes from the target sequence, multiple sirnas for the same target, and rescue by expression of target sequences refractory to sirna. Transcription and RNA processing Studies that identify new regulatory elements and the factors that bind them and provide new and significant insights into processes of gene expression or regulation. Manuscripts that identify methylated sites in a gene or promoter, or demonstrate that the methylation status of a gene correlates with gene expression, and provide new and significant insight into how methylation is controlled or how methylation controls gene expression. Transgenics and knockouts Manuscripts that report the generation of transgenic or knockout mutants that provide new insights into biological processes on a molecular or cellular level.

26 What You Need to Submit When you are ready to submit, you will need: A PDF file containing text, figures, tables, references in JBC format (under 10 MB) A cover letter Summary/abstract (under 250 words) Contact information for all authors (name, institution, address) A running title Preference section of the Journal (can be cross-listed) Suggested reviewers (preferably from the JBC editorial board)

27 Questions/Comments?