/ E-Mental health June 11, 2018 / / e-health developer point of view / Emmanuel Cordonnier

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1 / E-Mental health June 11, 2018 / / e-health developer point of view / Emmanuel Cordonnier

2 <Institute of Research & Technology> b<>com is a private French innovation center designed to boost innovation in digital technologies. A unique co-investment model that provides knowledge, know-how and technology. Public distribution 2

3 <mixing skills> Engineer Legal Developer Surgeon Ergonomist Researcher Marketer UX Designer Public distribution 3

4 Our vision for future of Healthcare Patient Doctor 3DP UHD HDR Integrated 5G Data Viz Personalized Distributed Image guided therapy Telemedicine Training, certification Translational research Deep learning Semantic web Big data VR AR Fog Cloud RGB-D CCN IoT Public 4

5 e-health: Key Components for better Healthcare Augmented Connected Key components 3D object localization Biomechanical organ tracking Automatic registration Image fusion Surgery live display Surgery planning Key components CT/MR slices viewer EEG signal viewer Live surgical video over IP Access authorization Ontologies Biomarkers b<>com *Surgery Workflow Toolbox* [Annotate] b<>com [Rest DICOM Library] Fields of use Fields of use Orthopedics Radiology Radiotherapy Neurology Neurosurgery Epidemiology Public 5

6 Multiple Sclerosis & Translational Research Several Molecules can slow down growth of lesions in MS Magnetic Resonance Imaging (MRI) is a good indicator MR Images can help clinician and patient to choose the pill But MR images are complicated to interpret Recent Algorithms (AI ) seem to be relevant But they are not stabilized yet Translational Research can accelerate the process Public 6

7 MUSIC: Translational Research (MS) Neurology 30 centers Radiology 50 centers Imaging Network RUBIS & ETIAM Image Processing & Quality Biotrial MS Clinic CHU Rennes Clinical Hosting SIB Research Hosting b<>com 17/12/2018 Restricted Public 7

8 MUSIC: deployment on actual patients 17/12/2018 Restricted Public 8

9 CONDOR: (Connected) OR of the Future 17/12/2018 Restricted Public 9

10 CONDOR: Reducing Adverse Events France: 8,000 OR 6.5 million surgical operations per year 75 thousands of serious adverse events per year (SAEs) compared to aviation and its 120 accidents in the world Surgery: Check list «Black Box» «Control Tower» «Communication standard» 17/12/2018 Public 10

11 CONDOR: Reducing Surgery Adverse Events the TV studios evolve from point to point to the whole IP Capacity x 15 Price / 2 new standard of medical real-time video (RTV) 4K medical ultra low latency encoder Automatic analysis, alerts, AR Supervision, patient flow, reporting Recognition, telemonitoring terminology 2017 to 2020 WG1 WG2 WG3 WG4 Equipment Reduce errors thanks to surgical control tower Operating room Department of Surgery Training 17/12/2018 Restricted Public 11

12 DICOM-RTV: New Standard for Real-Time Medical Video xxscope overhead camera Universal Time decoders Secondary Display ultrasound/x-ray ECG monitoring encoders Surgery Dept Network mosaic processor combination proc. Mosaic Displays Combination Displays DICOM viewer streamer Distribution video (SDI ) DICOM DIMSE (TCP/IP) DICOM RTV (RTP/IP) Universal Time (PTP/IP) Others (management ) Operating Room Management Configuration, Scheduler storage/playback Cloud Disk Hospital Network archive (P/MACS) 17/12/2018 Restricted Public 12

13 FollowKnee: Connected Knee Prosthesis Knee Osteoarthritis A Major Societal Challenge 1 baby boom seniors 2 Obesity Growth 3 Young Active people ( > 50%, 2011) From 2005 to % Procedures in millions In the US [2] + 601% of procedure revisions in 2030 (268,000 in the US) Non relevant Prostheses Wrong implantations Aseptic Mechanical (49.9 %) Prosthesis Loosening Skeptical Infection (16.2 %) Late Diagnosis Surgery Resumption Cost (X 2.5), Iatrogenic (More complications, Poor functional results) Personalized Therapy 12/17/2018 Restricted Public 13

14 FollowKnee: Connected Knee Prosthesis Acquisition & Planning Patient s CT Follow up Automatic Planning Software Implant & Follow Up Augmented Reality Assisted Procedure Personalized Prosthesis and Tools Integrated Sensors Design / Manufacturing 12/17/2018 Restricted Public 14

15 Needle Guided Therapy Biopsy Prostate Brachytherapy Liver Iode-125 (half-life 60 days) Dosimetry Kidney Prostate Trans-rectal US probe Trans-perineal seeds insertion 17/12/2018 Restricted Public 15

16 PEPS: 3D DataViz of Patient s Path 17/12/2018 Restricted Public 16

17 Thanks / emmanuel.cordonnier@b-com.com /