4 th International Advanced ICAS Training Course on "Blood Stem Cell Transplantation: State of the Arts, Methods, Perspectives" April 2007

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1 4 th International Advanced ICAS Training Course on "Blood Stem Cell Transplantation: State of the Arts, Methods, Perspectives" April 2007 at the and Institute of Transfusion Medicine (Building of the DRK-Blutspendezentrale) Campus of the University of Ulm Course Directors: Professor Dr. Klaus-Michael Debatin Professor Dr. Hartmut Doehner Professor Dr. Hubert Schrezenmeier Final Program Monday, 16 April h Registration h Welcome: Opening Ceremony Professor Dr. Klaus-Michael Debatin Dean, University of Ulm Session I: Biology of Hemopoietic Stem Cells h Immunophenotypic and Functional Characterization of Hemopoietic Stem Cells Dr. Greg Terszowski Institute of Immunology, University of Ulm h Characteristics of Human Hemopoietic Stem Cells Professor Dr. Rainer Haas Director, Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf Session II: Hemopoietic Stem Cell Transplantation: Principles h Molecular Heterogeneity of AML and Implications for Stem Cell Transplantation Professor Dr. Hartmut Doehner Director, h Lunch h Autologous Transplantation: Clinical Indications, Future Perspectives, and Potential Complications Dr. Martin Bommer

2 ICAS 2007: Blood Stem Cell Transplantation page 2 of 5 Session III: Collection and Storage of Hemopoietic Stem Cells h Preparation of Patients and Donors, Stem Cell Collection: Risks and Side Effects Dr. Peter Reinhardt h Coffee break h Cryopreservation of Hemopoietic Stem Cells Dr. Volker Mailaender Session IV: Allogeneic Stem Cell Transplantation: Conditioning h Conventional and New Forms of Conditioning Regimens Professor Dr. Donald Bunjes h Clinical Round: Clinic of Pediatrics, University of Ulm Tuesday, 17 April 2007 Session V: Allogeneic Stem Cell Transplantation: Donor Search h Methods of HLA Typing PD Dr. Joannis Mytilineos h Finding an Appropriate Related or Unrelated Donor Dr. Dr. Carlheinz Mueller German National Bone Marrow Donor Registry, Ulm h Coffee break Session VI: Stem Cell Transplantation for AML h Stem Cell Transplantation in Pediatric Diseases: Leukemias and Inborn Errors PD Dr. Ansgar Schulz Clinic of Pediatrics, University of Ulm Session VII: Mesenchymal Stem Cells h Mesenchymal Stem Cells: Isolation, Expansion and Potential Clinical Use Prof. Dr. Hubert Schrezenmeier Director,, h Lunch

3 ICAS 2007: Blood Stem Cell Transplantation page 3 of h Introduction to Practical Exercises I h Dr. Markus Wiesneth h - Practical Exercises: I h (2 groups of 6-8 participants) HLA-Typing, Donor Search PD Dr. Joannis Mytilineos h h Group A h h Group B Mesenchymal Stem Cells Dr. Markus Rojewski h Coffee break h h Group B h h Group A h Clinical Round: Wednesday, 18 April h Introduction to Practical Exercises II Dr. Markus Wiesneth h - Practical Exercises: I h (2 groups of 6-8 participants) h Coffee break Stem Cell Products I: Quality Control, Assays of Committed Progenitor Cells Dr. Klaus Schwarz / Martina Schlaier h h Group A h h Group B Stem Cell Products II: Preparation, CD34 Selection, and T-Cell Depletion Dr. Markus Wiesneth / Birgit Maccari h h Group B h h Group A

4 ICAS 2007: Blood Stem Cell Transplantation page 4 of h - Practical Exercises: III h (2 groups of 6-8 participants) h - Lunch h Stem Cell Products III: Collection/Apheresis Dr. Peter Reinhardt h h Group A h h Group B FACS Analysis, Chimerism Analysis (two subgroups) Dr. Peter Schauwecker / Dr. Martin Marx h h Group B h h Group A h - Practical Exercises: IV h (2 groups of 6-8 participants) h - Coffee break h Stem Cell Products IV: Cryopreservation and Storage Dr. Volker Mailaender h h Group A h h Group B Donor Registry and Donor Work Up Dr. Dr. Carlheinz Mueller h h Group B h h Group A h End of exercises h Guided tour through the old part of the city of Ulm (Meeting point: Tourist-Information at the Stadthaus Ulm [modern white building in front of the Muenster Cathedral]) h Guided tour ends with a dinner invitation for all participants and lecturers at the "Zunfthaus der Schiffleute", Fischerviertel Thursday, 19 April 2007 Session VIII: Special Aspects h Clinical Management of Patients Before, During, and After Stem Cell Transplantation Dr. Mark Ringhoffer

5 ICAS 2007: Blood Stem Cell Transplantation page 5 of h Supportive Therapy in Stem Cell Transplantation Dr. Stephanie von Harsdorf h Coffee break h Pathophysiology and Diagnosis of Congenital Immunodeficiencies Dr. Klaus Schwarz h Stem Cell Transplantation in Pediatric Diseases: Congenital Immunodeficiencies Dr. Manfred Hoenig Clinic of Pediatrics, University of Ulm h Immune Reconstitution after Stem Cell Transplantation Dr. Susanna Mueller Institute of Immunology, University of Ulm h Lunch Session IX: Cord Blood Stem Cells h Cord Blood Stem Cells and Their Use and Potentials Professor Dr. Hermann Eichler University Homburg/Saar Session X: Regulatory Aspects h Stem Cell Therapy: legal Prerequisites in Europe and Germany Dr. Helga Marie Huber, Paul-Ehrlich-Institute, Langen h Final Discussion, Course Evaluation, and Hand-out of Certificates Professor Dr. Theodor M. Fliedner Director of ICAS, University of Ulm