Oxford Gene Technology The Molecular Genetics Company

Transcription

1 Oxford Gene Technology The Molecular Genetics Company CYTOCELL USER GROUP MEETING 2017 Spencer Howell VP European Sales April

2 Welcome everybody Many thanks for your huge interest and fantastic feedback! A warm welcome to our Guest speaker Cyto (selling) non-human FISH probes Prof.. Darren Griffin School of Biosciences, University of Kent A warm welcome to everyone and especially our speakers. We are pleased to welcome participants from the Netherlands and UK. 2

3 Overview Short introduction to OGT and the current product range Agenda of the CYTOCELL USER GROUP MEETING 2017

4 Oxford Gene Technology (OGT) Advancing molecular medicine Founded by Professor Sir Ed Southern in 1995, the inventor of the Southern blot and microarray technology Focused on delivering highly accurate detection and interpretation of genetic disorders Based in Oxford (UK), Cambridge (UK) and New York (USA) Now selling products and services for cytogenetics and genomics in 60 countries worldwide 4 4

5 Customisation The complete solution for molecular genetics Integrated product portfolio Array products Cytogenetics Molecular genetics Cancer Pre-implantation genetics screening Reagents Interpretation sw NGS products Hybridisation enrichment panels Ovarian and breast panels MPN, Myeloid and AML panels FH panel Reagents Library preparation kit FFPE repair kit Analysis software FISH probes Haematology Pathology Constitutional myprobes 5

6 CytoSure The complete solution for cytogenetics research 6

7 CytoSure Extensive product range Constitutional genetics research Developmental delay Cancer cytogenetics research Leukaemia, myeloma Molecular genetics research Heart disease, diabetes Pre-implantation genetic screening (PGS) Reproductive health/ivf Arrays CytoSure Constitutional v3/v3 +LOH CytoSure ISCA v2/v2 +SNP CytoSure Cancer +SNP CytoSure Haematological Cancer +SNP CytoSure Molecular Arrays & Custom CytoSure Medical Research Exome CytoSure Embryo Screen Reagents CytoSure Genomic DNA Labelling Kits Automation Full automation options Software CytoSure Interpret Software Meaningful results 7

8 SureSeq NGS solutions Overview Hybridisation based enrichment unsurpassed coverage uniformity and reliability. Eliminate Sanger gap filling. Targeted panels evidence-based content designed by experts in their field, focused on relevant variants. Increase efficiencies. Streamlined library preparation highest quality libraries, from FFPE material. Productive answers from difficult samples. Complimentary analysis software intuitive reports fully annotated to multiple databases Customisation your ideal targeted panel designed with our in-house experts 8

9 SureSeq mypanel Customisation AML,CLL,CML,MPN,MPN/MDS overlap,breast cancer,colorectal,lung,melanoma 9

10 Cytocell FISH-based diagnostics Founded in 1991 A leading provider of FISH probes for detection of genetic disease and cancer Operations in Cambridge, UK with 30 employees Over 400 products sold to over 60 countries both Direct and through distributors Products CE-Marked for sale in Europe and sold as Analyte Specific Reagents (ASRs) in the US 10

11 Cytocell FISH-based diagnostics Aquarius Haematology Probes Aquarius Pathology Range Aquarius Haematopathology Range Aquarius Telomere Specific Probes / Whole Chromosome Painting Probes / Satellite Probes Aquarius Microdeletions Probes Aquarius Prenatal Probes Aquarius Murine Chromosome Whole Painting Probes Multiprobe AML/ALL/CLL/Sub-T/Paints Ancillary Components and Fluorescence Filters myprobes - Custom Probe 11

12 Cytocell product overview Product / Service range Description Directly labelled liquid probes provided in hybridisation solution Custom probes rapid development and manufacture leading to potential catalogue products Multiple probes reversibly bound to a glass slide providing a convenient screening tool for genetic abnormalities across multiple chromosomes Zoofish Multiprobe devices for animal species e.g. mice, pigs and chickens (cattle in progress) 12

13 Agenda review 13

14 Agenda review 14

15 Oxford Gene Technology The Molecular Genetics Company CytoSure and SureSeq : For Research Use Only; Not for Use in Diagnostic Procedures. Cytocell: Some products may not be available in the US. 15