New Health Data Economy: Strategic Partnerships with Life Sciences Company

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1 New Health Data Economy: Strategic Partnerships with Life Sciences Company Pravin R Jadhav Sr. Director, Innovative Data Solutions Otsuka Data Sciences Otsuka Pharmaceutical Development and Commercialization Princeton, NJ May 9, 2016

2 Outline Otsuka Strategic Partnerships Changing Landscape for Pharma Industry Changing Talent Needs

3 Otsuka Strategic Partnership Otsuka- Proteus Health Examples Otsuka- IBM

4 Changing Business for Pharmaceutical Industry THE NEED TO GO BEYOND DELIVERING BLOCKBUSTER More focus on Biotech products Unique processes Regulatory hurdles Patent cliff Lost $50b in 3 years in 2010 Losing $188b in sales by 2023 Bargaining Power of Suppliers Threat of Substitutes Industry Rivalry Threat of New Entrants Bargaining Power of Buyers Increasing competition Despite high barrier to entry create to sell model on the rise Technology companies entering the market Increasing influence of payers Diminishing roles of GPs Regulatory involvement Your Logo

5 Pharmaceutical Industry is Focusing on Integrated Therapeutics Strategy in addition to Blockbusters INNOVATOR/ADAPTER Integrated therapeutics strategy Leverage mhealth clinical trials to build digital vision with the product Year Traditional Drug Discovery/Development Year Year 2-3 Years 1-2 Years 4-6 Years Target Identification Target Validation Lead identification Candidate Optimization Pre-Clinical Clinical Drug Discovery/Development in the Digital Era Big Data Target Identification Target Validation Lead Identificatio n Candidate Optimization Integrated Therapeutics Strategy for the Real World (digital solutions, behavioral interventions, other therapeutic options etc.) Pre-Clinical Clinical Real world

6 Real World Translation INNOVATOR/ADAPTER Have you treated a patient like me? Integrated therapeutics strategy Leverage mhealth for clinical trials to build digital vision with the product Capture data to enable translation Continue translation post launch Wearables Insideables Behavioral Harness knowledge from all therapeutic encounters -LEARNING SYSTEM- Develop smart analytics and knowledgebase Translation to clinical decisions -REAL WORLD TRANSLATION AT LAUNCH-

7 Big (Smart) Data and Analytics Opportunities ANALYTICS OPPORTUNITIES DATA OPPORTUNITIES Provider tools Enable informed decision making at the bedside Up to date guidelines Omics Genomic, proteomic, microbiome etc Analytic Platforms Shared with payer and providers Economic Socio-economic data Behavioral Lifestyle behaviors Decision Support Clinical decision support system and treatment guidelines Real time alert system Social Leverage social media Build community Apps and Devices Patient engagement Progress/Feedback/Guidanc e EMR Medical records

8 Changing Talent Needs

9 Three Key Attributes for Quantitative Scientists to Deliver the Integrated Therapeutics Vision Data Scientist Integrates data from disparate sources Unlocks Information from Data Drug Developer Translates knowledge for drug development problem Delivers decision using the knowledge Disease Area Expert Leverages Disease area expertise with quantitative knowledge Creates knowledge from Information