VIJAYA COLLEGE. R.V Road, Basavanagudi, Bengaluru (Accredited by NAAC with B++ Grade) DEPARTMENT OF GENETICS

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1 VIJAYA COLLEGE R.V Road, Basavanagudi, Bengaluru (Accredited by NAAC with B++ Grade) JULY AUGUST SEPTEMBER DEPARTMENT OF GENETICS ACADEMIC PLANNER FOR I, III & V SEMESTER B.Sc.(Odd) B.Sc. I Semester NUMBER OF HOURS Microscopy- Compound (dark field and bright field), fluorescent. Phase Contrast and Electron Microscope. Life cycle of neurospora, C.elegans. Cell theory. Prokaryotic and Eukaryotic cell. Cell cycle. Cell division-mitosis. Ultrastructure, Chemical Composition,and functions of Endoplasmic Reticulum, Ribosomes, Centrosomes. Bombyx mori, Arabidopsis thaliana. Meiosis- stages and significance. Apoptosismechanisim and significance. TMV virus, Bacteria- E coli, Bacteriophage-lambda. Ultrastructure, chemical composition,and functions of lysosomes, golgicomplex and peroxisomes. Cell wall: structure and function. Extra cellular matrix. Cytoskeletal Structure- Actin and Microtubule. Drosophilla, mosquito OCTOBER 6hrs 6hrs Ultrastructure, Chemical Composition, and Functions of Mitochondria, Plastids and Nucleus Plasma Membrane: Structure, Chemical Composition and functions. Microvilli and Desmosomes.

2 B.Sc. III Semester JULY AUGUST SEPTEMBER OCTOBER NUMBER OF HOURS 6hrs 6hrs Linkage: Coupling and repulsion hypothesis, linkage in Maize and Drosophila, factors affecting linkage,theories Chromosomal theory of inheritance, structure of eukaryotic chromosome, ultrastructure, euchromatin, heterochromatin, karyotype and idiogram Crossing over: definition, types, crossing over in Drosophila. Theories. Interference and coincidence. Construction of Genetic maps Chromosomal aberrations- numerical And structural. Mechanism of crossing over, tetrad analysis of neurospora. Special types of chromosomes- Polytene, Lamp brush and B chromosomes Sex linkage- Bridges theory. Sex linkage in Drosophila, Maize and poultry. Attached X chromosomes Extra chromosomal inheritance- Mt DNA, Ct DNA. Sigma factor in drosophila, kappa particles in paramecium. CMS in crop plants and its commercial exploitation

3 B.Sc. V Semester (PAPERV) JULY AUGUST SEPTEMBER OCTOBER NUMBER OF HOURS hrs 2hrs 2hrs GK GK GK SJ GK Techniques for recombinant DNA technology Introduction to genetic engineering and cloning. restriction enzymes in cloning, types nomenclature, DNA ligase and co-factors Direct gene transfer- liposomes, chemical methods Sequencing of gene- Maxam Gilbert, and Sangers Method Other enzymes used in Genetic Engineering. Blotting techniques- Southern, Northern, Western, Dot blots and Slot blots Electroporation, Micrioinjection, Shot Gun Method. Introduction to selection and screening of recombinants Synthesis of Gene- t RNA synthesis, Interferon Gene synthesis Cloning vectors- Plasmid, CMV,M 13,Simian Virus Direct and Indirect Methods of Screening Application of Genetic Engineering, transgenic crops and animals. Ti and Cosmids, Gemini Virus, vaccinia,retro Virus, and Lambda Selectable and Scorable Reporter Genes. Expression of Cloned Genes

4 B.Sc. V Semester (PAPERVI) JULY AUGUST SEPTEMBER OCTOBER NUMBER OF HOURS 4hr 2hrs 6hrs 3hrs Pedigree studies and genetic counseling Human chromosomes-introduction and classification Karyotyping of normal and abnormal chromosomes. Flow cytometry Immunology and immunogenetics Autosomal dominant inheritance, pedigree chart, analysis. Autosomal recessive inheritance with examples. Dermatoglyphics, Prenatal diagnosis X linked inheritance, y linked inheritance and multifactorial inheritance with examples, pedigree studies. Oncogenetics, Genetics and society Multifactorial Inheritance and Mitochondrial Diseases.

5 VIJAYA COLLEGE R.V Road, Basavanagudi, Bengaluru ( Accredited by NAAC with A + Grade) DEPARTMENT OF GENETICS ACADEMIC PLANNER FOR I, III & V SEMESTER B.Sc.(EVEN) B.Sc. II SEMESTER JANUARY NUMBER OF HOURS UNIT-6 MULTIPLE ALLELES: DEFINITION, EYE COLOR IN DROSOPHILA, BLOOD GROUPS AND Rh FACTOR IN HUMAN. GENETIC PROBLEM UNIT-4 ELEMENTS OF BIOMETRY: MEASURES OF CENTRAL TENDENCY; MEAN, MEDIAN,MODE FEBRAURY UNIT-2 BIOGRAPHY OF MENDEL. UNIT-7 GENE INTERACTIONS INTER ALLELIC GENE INTERACTION, DOMINANT EPISTASIS, RECESSIVE EPISTASIS WITH SUITABLE EXAMPLES. UNIT-1 HISTORY OF GENETICS- PRE MENDELIAN GENETIC CONCEPTS- PRE FORMATION,EPIGENESIS, PANGENESIS, INHERITANCE OF ACQUIRED CHARACTERS, GERMPLASM THEORY. HEREDITY AND ENVIRONMENT: GENOTYPE AND PHENOTYPE. HERIDITY AND VARIATION

6 CLONES, PURELINES AND INBRED LINES NORMS OF REACTION AND PHENOCOPIES MARCH APRIL UNIT-4 MEASURES OF DISPERSION- RANGE, STANDARD DEVIATION. UNIT-7 DOMINANT EPISTASIS, RECESSIVE EPISTASIS WITH SUITABLE EXAMPLES. UNIT-3LAW OF SEGREGATION: MONOHYBRID CROSS, DOMINANCE,CO- DOMINANCE AND INCOMPLETE DOMINANCE. GENETIC PROBLEMS LAW OF INDEPENDENT ASSORTMENT: DI-HYBRID CROSS, BACK CROSS, GENETIC PROBLEMS. TEST OF HYPOTHESIS- STUDENTS t TEST UNIT-8 SEX DETERMINATION- CHROMOSOMAL THEORY OF SEX DETERMINATION. HARMONAL CONTROL OF SEX DETERMINATION. DOSAGE COMPENSATION IN DROSOPHILA AND HUMAN UNIT-4 TEST OF HYPOTHESIS- STUDENTS t TEST. CHI SQUARE TEST. PROBABILITY- NORMAL BINOMIAL AND POISSON DISTRIBUTION.

7 B.Sc., IV SEMESTER JANUARY FEBRUARY MARCH APRIL NUMBER OF HOURS UNIT-1 INTRODUCTION TO MOLECULAR GENETICS: CHEMICAL BASIS OF HEREDITY: DNA AS A GENETIC MATERIAL-EXPERIMENT OF GRIFFITH, AVERY, Mc CLOID AND Mc CARTHY. UNIT-4 GENETIC CODE: FEATURES UNIT-1 RNA AS AGENETIC MATERIAL:EXPERIMENTS OF HARSHEY AND CHASE RNA TYPES AND STRUCTURE, UNIT-2 DNA STRUCTURE AND TYPES. RNA TYPES AND STRUCTURE. RIBOZYMES. UNIT-5: PROTEINSYNTHESIS- TRANSCRIPTION IN PROKARYOTES AND EUKARYOTES UNIT-3 REPLICATION IN PROKARYOTES AND EUKARYOTES. UNIT-7 GENETICS OF BACTERIA UNIT-4 TRANSLATION IN PROKARYOTES AND EUKARYOTES UNIT-4 GENOME ORGANISATION AND FINE STRUCTURE OF GENE. UNIT-6 TRANSPOSABLE ELEMENTS UNIT-9 INTRODUCTION TO GENOMICS AND PROTEOMICS UNIT-4 REGULATION OF GENE EXPRESSION: Lac OPERON, GALACTOSE AND TRYPTOPHANE. UNIT-8 GENE MUTATION

8 B.Sc VI SEMESTER (Paper-VII) JANUARY FEBRUARY NUMBER OF HOURS 2hrs UNIT-2:Evolutionary genetics: Mutation theory, Neo -Darwinism, speciation and its methods UNIT-1 Developmental genetics Factors controlling development, nuclear transplantation, fate mapping. UNIT-2 Evolution at molecular level, isolating mechanism, speciation methods. UNIT-3 Population genetics; Gene pool gene frequency Hardy- Weinberg law, Evolutionary agents UNIT-1 Developmental genetics Differential expression of haemoglobin genes. Genetics of development in Arabidopsis. MARCH SJ UNIT-4 Quantitative characters and inheritance quantitative characters- types and features of polygenic traits. Transgressive inheritance. UNIT-1 Developmental genetics Genetics of Development in Drosophila.

9 APRIL UNIT-5 Biometrical genetics: ANOVA analysis. variances in polygenic traits, heritability, quantitative trait loci. Significance of polygenic inheritance. Problems related to variance and heritability. UNIT-1 Developmental genetics Role of maternal genes in Drosophila B.Sc VI SEMESTER (PAPERVIII) DECEMBER JANUARY NUMBER OF HOURS 2hrs UNIT-3 Genetics resources and biodiversity Germplasm,classification and activities UNIT -6 Bioinformatics Introduction world wide web-types of web sites. bioinformatics in genome analysis UNIT-3 Genetics resources and biodiversity Genetic erosion and gene sanctuaries UNIT-2 DNA fingerprinting and its applications

10 FEBRAURY MARCH SJ UNIT-5 Introduction to plant tissue cultureembryo,anther, ovary, shoot and root cultures UNIT-4. Heterosis: Breeding in animals and crop plants UNIT-1 Genetics in medicine and industry UNIT-1 Preparation of DNA probes UNIT-4 Heterosis: Breeding in animals and crop plants UNIT-2 Molecular markers- RFLP and RAPD and application UNIT-5 callus culture, protoplast culture economic benefits of plant tissue culture