THE FUTURE OF HEALTH IS BEING INVENTED IN NANTES SAINT-NAZAIRE

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1 JOIN A RICH ECOSYSTEM Atlanpole Science a Technology Park, European Business & Innovation Center, Regional Incubator for the Pays de la Loire. Atlanpole Biothérapies Competitiveness cluster with 30 members focused on immuno-biotherapies, regenerative medicine, innovative technologies for biotherapies a radiopharmaceuticals. NANTES SAINT-NAZAIRE DÉVELOPPEMENT FACILITATES YOUR PROJECTS: OUR ECONOMIC DEVELOPMENT AGENCY IS THERE TO MAKE IT EASY FOR YOU! The French HealthTech network Creative Care Factory Cluster of Cultural a Creative Iustries bringing together a community of actors a innovative projects in the fields of health, wellness a prevention. has certified NantesTech We seek out a la or property solution to match your needs DO YOU WANT TO START A BUSINESS IN NANTES SAINT-NAZAIRE? They chose to invest in Nantes Saint-Nazaire GROUPS AND MULTINATIONALS We assist you to recruit your talents a staff We introduce you to the local networks a ecosystem that will help develop your business : healthcare institutions, academic research a universities, iustry a startups, venture capital a investment fus We provide you with the economic data that will facilitate your decision-making B I O F O R T I S M É R I E U X l B I O L O G I C A L E l B O I R O N l C I T O X L A B AT L A N B I O l C H R I S T E Y N S E F S - AT L A N T I C B I O G M P l E U R O F I N S l L N A S A N T E l P H I L I P S H E A LT H C A R E l T H E R M O F I S H E R l VA L N E VA We welcome employees that will be moving with you, by giving them personalized support : assistance to fi accommodation, job for the spouse, schools SMEs AND STARTUPS A F F I L O G I C l AT L A N TA G R O U P l H O R A M A l I N F L E C T I S B I O S C I E N C E l K E O S Y S l L E M E R PA X MYELOMAX l NEOSTEO l OSE IMMUNOTHERAPEUTICS l OWKIN l PHERECYDES PHARMA l XENOTHERA The city of Nantes offers numerous advantages, such as a fabric of biotechnology companies, an array of high-level public a academic research teams, significant public incentives that help biotechnology SMEs a a high-quality living environment, a all while maintaining very accessible operating costs. OWKIN Camille Marini PHERECYDES PHARMA Jérôme Gabard Technical Director of the Machine Learning platform CEO THE FUTURE OF HEALTH IS BEING INVENTED IN NANTES SAINT-NAZAIRE Mathieu Evrard +33 (0) mathieu.evrard@nantes-saintnazaire.fr HERE S WHAT THEY SAY There were two main reasons why we decided to set up in Nantes: the proximity to Paris a the partnership with the University Hospital, which has just the right size to remain agile. As a dynamic a efficient hospital, it provides effective support for the companies it collaborates with. YOUR CONTACT: For us, local anchoring is essential to the good performance of the company, a the Nantes environment is instrumental in this dynamic. We have an active a large ecosystem that enables every player to be identified. This facilitates collaborations a partnerships, especially with bodies such as the Gérontopôle of Pays de la Loire (ageing a longevity cluster), Atlanpole a Nantes Métropole. LNA SANTÉ Willy Siret Chief Operating Officer agence@nantes-saintnazaire.fr +33(0) Conception : Vu Par... Impression : VAL PG 50 copies October 018 Copyrights : Valneva - Stéphane Bellanger Art & Build Architecte/Pargade The future University Hospital of Nantes

2 KEY FIGURES FOR THE HEALTH SECTOR WELCOME TO NANTES SAINT-NAZAIRE! airdon ON Lby AMSTERDAM NANTES UNIVERSITY HOSPITAL Amsterdam Loon Berlin Brussels 9 sites,500 beds 1,500 employees 1H0 1 major seaport UNIVERSITY OF NANTES 1,00 1H OUTSTANDING RESEARCH TEAMS FROM : FIELDS OF EXCELLENCE physicians COMPANIES AND RESEARCH H by train 1H15 Geneva Lyon 1 airport connected to more than 80 international destinations University of Nantes Oniris Veterinary a Agri-Food School Centrale Nantes Polytech Nantes Audencia Business School IMT Atlantique Icam Nantes University Hospital University of Nantes Cancer Institute of Western France INSERM CNRS INRA Oniris a more Nantes Saint-Nazaire A LEADING CENTRE OF HIGHER EDUCATION : than 5,000 students in the Faculty of Medicine 700 students in the Faculty of Pharmacy including Paris 30 million metric tons a year direct a iirect jobs Connections to over 450 ports worldwide EUROPEAN LEADER FOR RESEARCH IN BIOTHERAPIES 10 businesses HAEMATOLOGY CARDIOVASCULAR AND THORACIC DISEASES 5,000 employees Milan TRANSPLANTATION CANCER than 30 biotechs emerging from academia CELL AND GENE THERAPY REGENERATIVE MEDICINE,500 health research staff DIGESTIVE SYSTEM DISEASES Roma Madrid DRID MA1H30 CANCER INSTITUTE OF WESTERN FRANCE 1,300 employees than 40,000 patients per year 1 st fastest growth in digital tech a iustrial jobs in France (01-017) fastest growth in traffic for a regional airport in France 800,000 inhabitants 1 million by 030 leading cancer center in terms of number of patients 60,000 students NUCLEAR MEDICINE AND RADIOPHARMACEUTICALS 3,400 employees 700 physicians within : Confluent Group, the leading iepeent clinic in France Hospi Gra Ouest A HEALTH CAMPUS AND THE FUTURE UNIVERSITY HOSPITAL BY 06 THE LARGEST HOSPITAL PROJECT IN FRANCE : 1 BILLION EUROS OF INVESTMENTS.3 billion euros in public investments by 03 1 billion euros of investments dedicated to a new hospital in line with the challenges of the Health of the Future a P4 Medicine IMMUNOBIOTHERAPY PRIVATE HOSPITALS AND CLINICS ELSAN Group 5,000 SQM IMMUNOLOGY 54 OPERATING THEATRES International winner of the European Healthcare Design Congress 018 in the category Future Healthcare Design 10 HECTARES OF TOTAL LAND AREA A unique opportunity to build a Health Campus where care, higher education, research a innovation converge REAL ESTATE SOLUTIONS FOR COMPANIES AT THE HEART OF THE ECOSYSTEM 1,880 progress at Nantes University Hospital 486 Both progress at the Cancer Institute of Western France institutions are certified «Early Phase Clinical Trial Center» in oncology 0 technological platforms in genomics, proteomics, functional exploration, bio-imaging, structural a metabolomic analysis, bio-informatics, microalgae (Algosolis)... ARRONAX Cyclotron: a state of the art equipment to produce innovative radio-isotopes for nuclear medicine a radiopharmacy IHU CESTI: University Hospital Institute - European Center for Transplantation a Immunotherapy Sciences NExT Nantes Excellence Trajectory : I-SITE accreditation, focused on the Health of the Future Technology Transfer Offices: SATT Ouest Valorisation a Capacités, private subsidiary of the University of Nantes Health Research Institute (IRS) - Nantes Biotech: a unique building gathering teams in infectious diseases, gene therapy a bio-statistics, a also open to companies

3 KEY FIGURES FOR THE HEALTH SECTOR WELCOME TO NANTES SAINT-NAZAIRE! airdon ON Lby AMSTERDAM NANTES UNIVERSITY HOSPITAL Amsterdam Loon Berlin Brussels 9 sites,500 beds 1,500 employees 1H0 1 major seaport UNIVERSITY OF NANTES 1,00 1H OUTSTANDING RESEARCH TEAMS FROM : FIELDS OF EXCELLENCE physicians COMPANIES AND RESEARCH H by train 1H15 Geneva Lyon 1 airport connected to more than 80 international destinations University of Nantes Oniris Veterinary a Agri-Food School Centrale Nantes Polytech Nantes Audencia Business School IMT Atlantique Icam Nantes University Hospital University of Nantes Cancer Institute of Western France INSERM CNRS INRA Oniris a more Nantes Saint-Nazaire A LEADING CENTRE OF HIGHER EDUCATION : than 5,000 students in the Faculty of Medicine 700 students in the Faculty of Pharmacy including Paris 30 million metric tons a year direct a iirect jobs Connections to over 450 ports worldwide EUROPEAN LEADER FOR RESEARCH IN BIOTHERAPIES 10 businesses HAEMATOLOGY CARDIOVASCULAR AND THORACIC DISEASES 5,000 employees Milan TRANSPLANTATION CANCER than 30 biotechs emerging from academia CELL AND GENE THERAPY REGENERATIVE MEDICINE,500 health research staff DIGESTIVE SYSTEM DISEASES Roma Madrid DRID MA1H30 CANCER INSTITUTE OF WESTERN FRANCE 1,300 employees than 40,000 patients per year 1 st fastest growth in digital tech a iustrial jobs in France (01-017) fastest growth in traffic for a regional airport in France 800,000 inhabitants 1 million by 030 leading cancer center in terms of number of patients 60,000 students NUCLEAR MEDICINE AND RADIOPHARMACEUTICALS 3,400 employees 700 physicians within : Confluent Group, the leading iepeent clinic in France Hospi Gra Ouest A HEALTH CAMPUS AND THE FUTURE UNIVERSITY HOSPITAL BY 06 THE LARGEST HOSPITAL PROJECT IN FRANCE : 1 BILLION EUROS OF INVESTMENTS.3 billion euros in public investments by 03 1 billion euros of investments dedicated to a new hospital in line with the challenges of the Health of the Future a P4 Medicine IMMUNOBIOTHERAPY PRIVATE HOSPITALS AND CLINICS ELSAN Group 5,000 SQM IMMUNOLOGY 54 OPERATING THEATRES International winner of the European Healthcare Design Congress 018 in the category Future Healthcare Design 10 HECTARES OF TOTAL LAND AREA A unique opportunity to build a Health Campus where care, higher education, research a innovation converge REAL ESTATE SOLUTIONS FOR COMPANIES AT THE HEART OF THE ECOSYSTEM 1,880 progress at Nantes University Hospital 486 Both progress at the Cancer Institute of Western France institutions are certified «Early Phase Clinical Trial Center» in oncology 0 technological platforms in genomics, proteomics, functional exploration, bio-imaging, structural a metabolomic analysis, bio-informatics, microalgae (Algosolis)... ARRONAX Cyclotron: a state of the art equipment to produce innovative radio-isotopes for nuclear medicine a radiopharmacy IHU CESTI: University Hospital Institute - European Center for Transplantation a Immunotherapy Sciences NExT Nantes Excellence Trajectory : I-SITE accreditation, focused on the Health of the Future Technology Transfer Offices: SATT Ouest Valorisation a Capacités, private subsidiary of the University of Nantes Health Research Institute (IRS) - Nantes Biotech: a unique building gathering teams in infectious diseases, gene therapy a bio-statistics, a also open to companies

4 KEY FIGURES FOR THE HEALTH SECTOR WELCOME TO NANTES SAINT-NAZAIRE! airdon ON Lby AMSTERDAM NANTES UNIVERSITY HOSPITAL Amsterdam Loon Berlin Brussels 9 sites,500 beds 1,500 employees 1H0 1 major seaport UNIVERSITY OF NANTES 1,00 1H OUTSTANDING RESEARCH TEAMS FROM : FIELDS OF EXCELLENCE physicians COMPANIES AND RESEARCH H by train 1H15 Geneva Lyon 1 airport connected to more than 80 international destinations University of Nantes Oniris Veterinary a Agri-Food School Centrale Nantes Polytech Nantes Audencia Business School IMT Atlantique Icam Nantes University Hospital University of Nantes Cancer Institute of Western France INSERM CNRS INRA Oniris a more Nantes Saint-Nazaire A LEADING CENTRE OF HIGHER EDUCATION : than 5,000 students in the Faculty of Medicine 700 students in the Faculty of Pharmacy including Paris 30 million metric tons a year direct a iirect jobs Connections to over 450 ports worldwide EUROPEAN LEADER FOR RESEARCH IN BIOTHERAPIES 10 businesses HAEMATOLOGY CARDIOVASCULAR AND THORACIC DISEASES 5,000 employees Milan TRANSPLANTATION CANCER than 30 biotechs emerging from academia CELL AND GENE THERAPY REGENERATIVE MEDICINE,500 health research staff DIGESTIVE SYSTEM DISEASES Roma Madrid DRID MA1H30 CANCER INSTITUTE OF WESTERN FRANCE 1,300 employees than 40,000 patients per year 1 st fastest growth in digital tech a iustrial jobs in France (01-017) fastest growth in traffic for a regional airport in France 800,000 inhabitants 1 million by 030 leading cancer center in terms of number of patients 60,000 students NUCLEAR MEDICINE AND RADIOPHARMACEUTICALS 3,400 employees 700 physicians within : Confluent Group, the leading iepeent clinic in France Hospi Gra Ouest A HEALTH CAMPUS AND THE FUTURE UNIVERSITY HOSPITAL BY 06 THE LARGEST HOSPITAL PROJECT IN FRANCE : 1 BILLION EUROS OF INVESTMENTS.3 billion euros in public investments by 03 1 billion euros of investments dedicated to a new hospital in line with the challenges of the Health of the Future a P4 Medicine IMMUNOBIOTHERAPY PRIVATE HOSPITALS AND CLINICS ELSAN Group 5,000 SQM IMMUNOLOGY 54 OPERATING THEATRES International winner of the European Healthcare Design Congress 018 in the category Future Healthcare Design 10 HECTARES OF TOTAL LAND AREA A unique opportunity to build a Health Campus where care, higher education, research a innovation converge REAL ESTATE SOLUTIONS FOR COMPANIES AT THE HEART OF THE ECOSYSTEM 1,880 progress at Nantes University Hospital 486 Both progress at the Cancer Institute of Western France institutions are certified «Early Phase Clinical Trial Center» in oncology 0 technological platforms in genomics, proteomics, functional exploration, bio-imaging, structural a metabolomic analysis, bio-informatics, microalgae (Algosolis)... ARRONAX Cyclotron: a state of the art equipment to produce innovative radio-isotopes for nuclear medicine a radiopharmacy IHU CESTI: University Hospital Institute - European Center for Transplantation a Immunotherapy Sciences NExT Nantes Excellence Trajectory : I-SITE accreditation, focused on the Health of the Future Technology Transfer Offices: SATT Ouest Valorisation a Capacités, private subsidiary of the University of Nantes Health Research Institute (IRS) - Nantes Biotech: a unique building gathering teams in infectious diseases, gene therapy a bio-statistics, a also open to companies

5 JOIN A RICH ECOSYSTEM Atlanpole Science a Technology Park, European Business & Innovation Center, Regional Incubator for the Pays de la Loire. Atlanpole Biothérapies Competitiveness cluster with 30 members focused on immuno-biotherapies, regenerative medicine, innovative technologies for biotherapies a radiopharmaceuticals. NANTES SAINT-NAZAIRE DÉVELOPPEMENT FACILITATES YOUR PROJECTS: OUR ECONOMIC DEVELOPMENT AGENCY IS THERE TO MAKE IT EASY FOR YOU! The French HealthTech network Creative Care Factory Cluster of Cultural a Creative Iustries bringing together a community of actors a innovative projects in the fields of health, wellness a prevention. has certified NantesTech We seek out a la or property solution to match your needs DO YOU WANT TO START A BUSINESS IN NANTES SAINT-NAZAIRE? They chose to invest in Nantes Saint-Nazaire GROUPS AND MULTINATIONALS We assist you to recruit your talents a staff We introduce you to the local networks a ecosystem that will help develop your business : healthcare institutions, academic research a universities, iustry a startups, venture capital a investment fus We provide you with the economic data that will facilitate your decision-making B I O F O R T I S M É R I E U X l B I O L O G I C A L E l B O I R O N l C I T O X L A B AT L A N B I O l C H R I S T E Y N S E F S - AT L A N T I C B I O G M P l E U R O F I N S l L N A S A N T E l P H I L I P S H E A LT H C A R E l T H E R M O F I S H E R l VA L N E VA We welcome employees that will be moving with you, by giving them personalized support : assistance to fi accommodation, job for the spouse, schools SMEs AND STARTUPS A F F I L O G I C l AT L A N TA G R O U P l H O R A M A l I N F L E C T I S B I O S C I E N C E l K E O S Y S l L E M E R PA X MYELOMAX l NEOSTEO l OSE IMMUNOTHERAPEUTICS l OWKIN l PHERECYDES PHARMA l XENOTHERA The city of Nantes offers numerous advantages, such as a fabric of biotechnology companies, an array of high-level public a academic research teams, significant public incentives that help biotechnology SMEs a a high-quality living environment, a all while maintaining very accessible operating costs. OWKIN Camille Marini PHERECYDES PHARMA Jérôme Gabard Technical Director of the Machine Learning platform CEO THE FUTURE OF HEALTH IS BEING INVENTED IN NANTES SAINT-NAZAIRE Mathieu Evrard +33 (0) mathieu.evrard@nantes-saintnazaire.fr HERE S WHAT THEY SAY There were two main reasons why we decided to set up in Nantes: the proximity to Paris a the partnership with the University Hospital, which has just the right size to remain agile. As a dynamic a efficient hospital, it provides effective support for the companies it collaborates with. YOUR CONTACT: For us, local anchoring is essential to the good performance of the company, a the Nantes environment is instrumental in this dynamic. We have an active a large ecosystem that enables every player to be identified. This facilitates collaborations a partnerships, especially with bodies such as the Gérontopôle of Pays de la Loire (ageing a longevity cluster), Atlanpole a Nantes Métropole. LNA SANTÉ Willy Siret Chief Operating Officer agence@nantes-saintnazaire.fr +33(0) Conception : Vu Par... Impression : VAL PG 50 copies October 018 Copyrights : Valneva - Stéphane Bellanger Art & Build Architecte/Pargade The future University Hospital of Nantes

6 JOIN A RICH ECOSYSTEM Atlanpole Science a Technology Park, European Business & Innovation Center, Regional Incubator for the Pays de la Loire. Atlanpole Biothérapies Competitiveness cluster with 30 members focused on immuno-biotherapies, regenerative medicine, innovative technologies for biotherapies a radiopharmaceuticals. NANTES SAINT-NAZAIRE DÉVELOPPEMENT FACILITATES YOUR PROJECTS: OUR ECONOMIC DEVELOPMENT AGENCY IS THERE TO MAKE IT EASY FOR YOU! The French HealthTech network Creative Care Factory Cluster of Cultural a Creative Iustries bringing together a community of actors a innovative projects in the fields of health, wellness a prevention. has certified NantesTech We seek out a la or property solution to match your needs DO YOU WANT TO START A BUSINESS IN NANTES SAINT-NAZAIRE? They chose to invest in Nantes Saint-Nazaire GROUPS AND MULTINATIONALS We assist you to recruit your talents a staff We introduce you to the local networks a ecosystem that will help develop your business : healthcare institutions, academic research a universities, iustry a startups, venture capital a investment fus We provide you with the economic data that will facilitate your decision-making B I O F O R T I S M É R I E U X l B I O L O G I C A L E l B O I R O N l C I T O X L A B AT L A N B I O l C H R I S T E Y N S E F S - AT L A N T I C B I O G M P l E U R O F I N S l L N A S A N T E l P H I L I P S H E A LT H C A R E l T H E R M O F I S H E R l VA L N E VA We welcome employees that will be moving with you, by giving them personalized support : assistance to fi accommodation, job for the spouse, schools SMEs AND STARTUPS A F F I L O G I C l AT L A N TA G R O U P l H O R A M A l I N F L E C T I S B I O S C I E N C E l K E O S Y S l L E M E R PA X MYELOMAX l NEOSTEO l OSE IMMUNOTHERAPEUTICS l OWKIN l PHERECYDES PHARMA l XENOTHERA The city of Nantes offers numerous advantages, such as a fabric of biotechnology companies, an array of high-level public a academic research teams, significant public incentives that help biotechnology SMEs a a high-quality living environment, a all while maintaining very accessible operating costs. OWKIN Camille Marini PHERECYDES PHARMA Jérôme Gabard Technical Director of the Machine Learning platform CEO THE FUTURE OF HEALTH IS BEING INVENTED IN NANTES SAINT-NAZAIRE Mathieu Evrard +33 (0) mathieu.evrard@nantes-saintnazaire.fr HERE S WHAT THEY SAY There were two main reasons why we decided to set up in Nantes: the proximity to Paris a the partnership with the University Hospital, which has just the right size to remain agile. As a dynamic a efficient hospital, it provides effective support for the companies it collaborates with. YOUR CONTACT: For us, local anchoring is essential to the good performance of the company, a the Nantes environment is instrumental in this dynamic. We have an active a large ecosystem that enables every player to be identified. This facilitates collaborations a partnerships, especially with bodies such as the Gérontopôle of Pays de la Loire (ageing a longevity cluster), Atlanpole a Nantes Métropole. LNA SANTÉ Willy Siret Chief Operating Officer agence@nantes-saintnazaire.fr +33(0) Conception : Vu Par... Impression : VAL PG 50 copies October 018 Copyrights : Valneva - Stéphane Bellanger Art & Build Architecte/Pargade The future University Hospital of Nantes