ASCP 2019 Baltimore Workshops for Laboratory Professionals May 7-10, Tuesday, May 7, 2019

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1 ASCP 2019 Baltimore Workshops for Laboratory Professionals May 7-10, 2019 Schedule and Session Descriptions: Tuesday, May 7, Clinical Chemistry: Review and Update Robert Christenson, PhD Professor of Pathology; Professor of Medical & Research Technology, University of Maryland Medical System, Baltimore, MD Larry A. Broussard, PhD, DABCC Professor Emeritus, Department of Clinical Laboratory Sciences, School of Allied Health Professions, LSU Health Sciences Center, New Orleans, LA Get up-to-date knowledge of critical areas in clinical chemistry: Biochemical Markers of Heart Disease: As we enter into the era of high-sensitivity cardiac troponin, it will be critical to understand how the laboratory and our clinical colleagues will be impacted. B-type natriuretic peptide and NT-proBNP biomarkers of hemodynamic stress that are available to assist in diagnosis, risk assessment and monitoring of heart failure and cardiovascular disease. Discover how to add value to the laboratory and its professionals. The need for knowledgeable consultation and collaboration between the laboratory and clinical areas has never been greater. Learn about introduction of new markers and for improved performance of established markers. Diabetes Mellitus: Learn about current recommendations for laboratory testing for the diagnosis and monitoring of diabetes, and the laboratory's role in detecting complications of uncontrolled diabetes. Discuss the current tests available and potential new markers for diabetes detection and monitoring of the diabetic patient. Liver Function and Dysfunction: The liver is susceptible to metabolic disease, attack by viruses and various toxins, as well as ischemia. Learn about the metabolite and enzyme analyses and various marker assays that are available for assessing liver function. Clinical and Workplace Toxicology Update: Gain in-depth knowledge about the drug tests available to the laboratory for purposes of detection and support of the overdosed patient, pain management and workplace regulations. Learn about new guidelines for workplace drug testing that can impact the clinical toxicology testing capability of your laboratory. List the biochemical markers that assist in diagnosis and monitoring of myocardial injury (MI) and heart failure. Specify guideline-directed use of biomarkers. Articulate the role of the laboratory in the diagnosis and monitoring of diabetes mellitus. List and explain hepatic physiology and the laboratory assays available to assess liver function and dysfunction. List and discuss recommended tests for the evaluation of patients suspected of drug overdose, patients being treated for pain management, and donors being evaluated for workplace purposes/incidents Update on Diagnostic Medical Parasitology 8:30 am - 5:00 pm 7.0 CMLE Credits Lynne S. Garcia, MS, CLS, MT, FAAM Director, LSG & Associates, Santa Monica, CA This presentation provides a review of important and emerging parasites and practical testing in Diagnostic Medical Parasitology, including routine, molecular, and STAT procedures. Topics will include patient profile information, specimen collection requirements, routine testing and special rapid tests, organism nomenclature, classification, morphology,

2 pathogenicity and test recommendations, and the clinical relevance of test results/reports/report comments. Various protozoa, helminths, and blood parasites will be included. Emerging and neglected parasitic infections within the US will also be covered. An extensive handout will also be provided. Discuss the pros and cons of practical diagnostic procedures in medical parasitology, including STAT requirements and molecular testing. Discuss the relevance of using fixatives with no mercury, no formalin, and no need for PVA or albumin. Describe the importance of report formats and report comments per results. List several emerging and/or neglected parasitic diseases within the U.S Management Rules and Tools: Your Primer for Success! 8:30 am - 5:00 pm 7.0 CMLE Credits Anthony Kurec, MS, H(ASCP)DLM Clinical Associate Professor, Emeritus, SUNY Upstate Medical University, Syracuse, NY If you want to jump start your supervisory career or enhance your laboratory management skills, this workshop is for you! Today s clinical laboratory is a highly complex and busy environment that requires skilled supervisors and managers who are well versed in the various aspects of management. But if you ve spent your formative years immersed in science and medicine or you ve recently taken on a management role you probably haven t had the opportunity or time to focus on all the management rules and tools that you need. This workshop will establish your professional development foundation, with essential information in the crucial management areas of finance, operations, human resources, and marketing/customer relations. Topics will include budgeting, leadership, regulatory issues, staff concerns, and much more! In addition, resources for further career enhancement will be provided. Discuss key elements in laboratory finances and perform test-cost and break-even analyses. Achieve quality laboratory services, using information, facility, risk, and safety management practices. Describe the four components in laboratory marketing. Apply appropriate skills in managing staff, including recruiting, maintaining, and professional development. Wednesday, May 8, A Case History Approach to a Review of Hematology Kathleen Finnegan, MS, MT(ASCP)SH CM Clinical Associate Professor, Clinical Laboratory Sciences, School of Health Technology and Management, Stony Brook University, Stony Brook, NY Examine all aspects of hematology by reviewing a series of case presentations. These case studies will be used to explain significant findings for a variety of hematologic disorders, including: acquired and inherited anemias nonmalignant white cell disorders acute and chronic leukemias myeloproliferative disorders

3 myelodysplastic syndromes The- WHO classifications, as well as additional confirmatory testing, will be discussed. Recognize morphologic changes and the identification of normal and abnormal cells. Correlate clinical data with hematologic disease states. Describe appropriate laboratory testing to identify and differentiate hematological disorders Passing Inspections: Practical Game Plans and Proven Strategies 8:30 am - 12:00 pm (Half-day Session) 3.5 CMLE Credits Sharon S. Ehrmeyer, PhD, MT(ASCP) Professor Emeritus, Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI Managers, supervisors, POCCs, and medical laboratory scientists preparing for an inspection, this session is for you! This program will provide a blueprint for developing strategies to successfully comply with the numerous and often confusing, regulatory requirements (CLIA, TJC, CAP, COLA). The workshop will provide an up-to-date assessment of the current regulatory environment, the latest changes to the requirements, the top 10 deficiencies cited, common pitfalls, and tactics to meet the surveyor/inspector and pass inspection with confidence! Following this session, you will be able to: Describe the latest testing regulations that will specifically impact your testing situation. Discuss common deficiencies and pitfalls cited by inspectors/surveyors. Develop strategies to identify and avoid inspection failures. Integrate workshop information to create an appropriate game plan for keeping inspection ready Improving Quality: QC is More than Statistics! 1:30 pm - 5:00 pm (Half-day Session) 3.5 CMLE Credits Sharon S. Ehrmeyer, PhD, MT(ASCP) Professor Emeritus, Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI Is your laboratory/poct QC program under development or in need of rejuvenation, or, should it be? Are you wondering how many controls are really needed, what QC approach/rule is the best to meet quality goals and regulatory requirements, how to interpret QC data and respond to out-of-control situations, and how to fit all this information into a total quality (risk) assessment process to ensure quality test results? If so, this workshop will provide you with basic information and tools to answer these questions. You will be able to apply the important elements of an effective QC program into strategies for ensuring quality test results. In addition, you ll gain an understanding of the importance of QC, including IQCP, in quality assessment and risk management. Audience participation and exercises will reinforce the information presented. Describe the key components of an effective quality control program. Compare and contrast current QC approaches to determine appropriate QC for your testing situation. Apply collected method performance verification data to QC rule selection. Evaluate and appropriately respond to QC data for corrective actions.

4 Examine current QC practices and transform them, if necessary, to valuable improvement activities for ensuring quality test results Creative Problem Solving Techniques You Can Apply Today! 8:30 am - 5:00 pm 7.0 CMLE Credits Anthony Kurec, MS, H(ASCP)DLM Clinical Associate Professor, Emeritus, SUNY Upstate Medical University, Syracuse, NY Baby-boomer retirement, new technology, decreasing laboratory reimbursements, staffing shortages, and the overarching goal of providing the best patient care... these are just a few of the challenges causing problems that demand creative solutions from everyone in the laboratory! Whatever your position in the laboratory, you can accomplish inventive and successful problem solving by utilizing appropriate techniques to correctly analyze a situation and achieve your desired goal. Attend this workshop to acquire those how-to procedures, which you can easily apply, even to complex situations such as instrumentation limitations, coworker concerns, quality assurance issues, timely reporting of results, and more. You'll learn how to best manage a problem to achieve a successful resolution and prevent future occurrences! Creating work teams by stimulating and implementing creative problem solving ideas that are not found in a procedure manual can be difficult if not nurtured properly. Short-term or easy fixes are often implemented with lackluster results. Whether you're a bench tech, lead tech, or a manager, successfully solving problems in a creative and successful manner can be better accomplished when one learns how to fully understand the problem(s) and utilize appropriate facilitating techniques to achieve the intended goals. These techniques can easily be applied by anyone, whether dealing with complex problem areas such as instrumentation limitations, co-worker concerns, quality assurance issues, poor turn- around times, phlebotomy errors, or timely reporting of results. Participants will learn how to best manage a problem and derive an outcome that successfully resolves and prevents future occurrences. Define and understand what is problem solving. Introduce proven steps to problem solve. Learn from simple exercises how to unlock your potential to create. Create milestones and develop metrics to assure the success of your solutions. Thursday, May 9, Introduction to Molecular Diagnostics: The How, What, and Why 6.5 CMLE credits William T. Bellamy, PhD, HCLD(ABB) Director, Molecular Diagnostics Division, Department of Pathology; Professor of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR Molecular diagnostics is one of the most rapidly growing disciplines within all clinical laboratories. Stay current with this indepth presentation! A review of the fundamental principles of molecular biology and nucleic acid chemistry, with emphasis on their application to human disease testing, will create a solid knowledge base in molecular diagnostics. Then, you ll hear a discussion of specimen handling and storage, and critical aspects of the isolation and purification of DNA and RNA. Practical aspects of a molecular diagnostic laboratory will be covered, including commonly utilized techniques and instrumentation. The workshop will highlight qualitative and quantitative polymerase chain reaction methodologies, fluorescence in situ hybridization (FISH), and

5 will touch on next generation sequencing. You ll learn how to establish a test menu, deal with local expertise and work force issues, and resolve variables associated with assay validation. You ll also learn about molecular testing for diagnosis and in monitoring patient response to drug therapy. Discuss essential concepts in molecular diagnostic testing. Describe current molecular approaches to disease diagnostics and screening. Explain key aspects involved in the setting up and running a molecular diagnostic laboratory. Develop a logical systematic procedure to analyze molecular targets important in diagnosis and monitoring of patient response to drug therapy Coagulation: What Makes It Go and What Holds It Back? Susan S. Graham, MS, MT(ASCP)SH CM Associate Professor and Chair, Department of Clinical Laboratory Science, SUNY Upstate Medical University, Syracuse, NY With advances in technology, coagulation studies have become more automated, making it difficult to fully appreciate the role hemostatic testing plays in patient care. Attend this session to maintain or increase your knowledge of this important area of the laboratory. The workshop will begin with a review of the physiological events associated with platelet plug formation and clot formation. These concepts will be applied in a discussion of screening studies and confirmatory testing for both primary and secondary hemostatic abnormalities. Algorithms and a case study format will contribute to an evaluative presentation of commonly encountered coagulation inhibitors, including anticoagulant and anti-platelet therapy and anti-phospholipid inhibitors. Describe the events that take place in primary and secondary hemostasis and identify potential coagulation inhibitors. Discuss the use of laboratory screening tests to evaluate hemostasis and develop algorithms to identify and confirm abnormalities. Interpret laboratory results, suggest additional testing, and identify hemostatic disorders by applying the concepts presented. New! 5771 From the Pisse Prophets to the Present: An Overview of Renal Function and Urinalysis 8:30 am - 4:00 pm 6.0 CMLE Credits Karol Sublett, MT(ASCP)SC CM Senior Educator, Indiana University Health Methodist Hospital, Clinical Laboratory Sciences Program, Indianapolis, IN This workshop will assist the laboratory generalist and Core Lab technologist to develop clinical correlation skills. The topics discussed will include renal function, renal diseases, BUN and creatinine, and urinalysis. The urinalysis portion will include a general review of the basic principles of the physical, chemical, and microscopic exam, including microscopic identification of cells, crystals, casts, and other findings in a urine sediment. There will be a special emphasis on correlating the above three portions of the urinalysis with disease conditions. There will also be a discussion on discrepant findings and corrective actions. Discuss the physiology and pathophysiology of the kidney, relating disease conditions to typical chemistry and urinalysis laboratory findings.

6 Discuss BUN and creatinine according to their normal formation, renal excretion, and disease states in which the laboratory values are abnormal. Understand the clinical usefulness of creatinine clearance testing. Identify the following in a urine sediment examination: cells, bacteria, casts, normal/ abnormal crystals, and other possible formed elements. Correlate physical, chemical, and microscopic findings in a urinalysis in order to identify reportable or discrepant findings. Friday, May 10, Body Fluids Improving Your Skills 8:30 am - 4:00 pm 6.0 CMLE Credits Maria L. Brock, MT(ASCP)SH; ART Manager of Hematology, Florida Hospital, Orlando, FL When it's up to you to perform body fluids analysis, are you comfortable with the various techniques? Would you like to gain new confidence in your ability to identify cellular and other elements? This workshop will provide valuable guidance for updating and enhancing your skills in this important area of the laboratory. You ll expand your knowledge base with an overview of the normal anatomy and physiology of the various body fluids, including cerebrospinal, pleural, peritoneal, pericardial, serous and synovial fluids. Normal laboratory findings will be analyzed for each body fluid, followed by a discussion on significant cellular findings on wet preparations and Wright-stained smears in correlation to the related disease state. Case histories will be presented to reinforce the information shared. Assess body fluids pre-analytically in preparation for testing. Recognize normal and abnormal cell lineage in body fluids. Describe the differential diagnosis of body fluids Blood Banking for the Generalist Jack A. Hager, MS, MT(ASCP)SBB Vice President, Laboratory Operations, QualTex Laboratories, San Antonio, TX Knowledge and skill with blood typing and antibody detection and identification are essential in transfusion services and donor centers to avoid mistakes or delays that can adversely affect patient care. But, as you rotate through the blood bank, are you unsure of the steps to take if you get a front and back type discrepancy or a positive antibody screen on a patient who has STAT blood bank needs? Do you need confidence when handling a call from the emergency room or surgery for results or products before the problems are fully resolved? Then, this workshop is for you! Specifically designed for laboratory professionals who need a blood bank refresher to upgrade their skills and become more valuable in the workplace, this presentation will focus on performing and interpreting front and back types, antigen screening, and antibody identification. The most prevalent RBC antigens and antibodies will be discussed to give you the knowledge and proficiency you need to increase your confidence to work in the blood bank, make decisions regarding type discrepancies and positive antibody screens, and deal with issuing non-type specific products or those that are not fully compatible. Exercises and case studies will reinforce the information presented.

7 Correctly apply the principles of the ABO system, discuss common variations of antigens and antibodies of the ABO system, identify and investigate common front/back type discrepancies and help guide physicians in selection of both type specific and type compatible products. Discuss the Rh System antigens and phenotype prevalence, and determine how and when to proceed with antigen screening and selection of antigen typed RBC to avoid sensitization. Distinguish clinically significant from clinically insignificant antibodies to other common blood group antigens, perform antibody screening and routine antibody identification and evaluate methods for antigen screening and cross match. New! 5998 Quality Begins with You Olga Kochar, MS, CSSGB Divisional Director, Laboratory and Transfusion Services, The George Washington University Hospital, Washington, DC This workshop will address the following concepts in QA utilizing interactive examples and case studies emphasizing real-life implementation in the lab setting: 1. Outline the overall Quality Management System concept why is it necessary and what were approaches that were used before. 2. Quality Management System and 12 Quality System Essentials as per CLIA concept. Outline of each of the elements and relevance to the Medical Technologists through examples and interactive discussions of each element to reinforce it conceptually. 3. Process Control and what can be done to ensure that every result, every time is reliable, dependable, and a quality result. 4. Nonconforming Event Management tools and tricks to use, effective investigations and documentation.