White Biotechnology Needs Green Backing!

Transcription

1 White Biotechnology Needs Green Backing! Dr. Ganesh M Kishore, PhD Spruce Capital Partners MLS CF I and II Montreal July

2 MLSCF MLSCF I, A $162M fund, fully committed MLSCF II, first closing at $150M in late 2014 and working towards a $ M final close by late 2015 Spruce Capital Partners (Drs. Wyse, Kishore and Mr. Young) and Xeraya Capital, co-manage MLSCF funds Investing globally in innovation-led in biogreentech ventures Addressing major opportunities in energy, food, feed, materials and wellness

3 MLSCF I Strategy and Execution Improving feedstock productivity Harvesting natural resources sustainably Efficiently converting biomass to feedstocks Addressing gaps in supply feedstock mix Next generation fine & specialty chemicals Health Care Investments, pertinent to ASEAN LSO, Sentinext, Cerca, BLSCF III Malaysian Industrial Biotech Expansion MYBIOMASS; SD-VERDEZYNE, CJ

4 MLS II Strategy and Status Addressing Unmet and/or Underserved opportunities in Agriculture Changing paradigm for industrial biotechnology Leveraging Data Analytics, Sensors, Robotics and Automation in Agricultural value chain UNDER WAY Human and Animal Nutrition to improve Health and Wellness Innovative applications for biochemicals food industry; materials and fibers 4

5 Major megatrends shape investments in life sciences Middle Class expected to be 4.9Billion people by 2030; 1.8 Billion today Consumption by this middle class expected to be $35 Trillion more than today ($21 T now) Most consumption growth in Asia (>75% growth) Growth in areas of Energy, Food, Materials, Health and Wellness 30-60% growth by 2030) Population contributes another billion people Understanding of Genome, enabled by IT, Miniaturization and automation AND CREATE SUBSTANTIAL OPPORTUNITIES FOR COMPETITIVE ENTERPRISES 3

6 Agriculture has to address both Quantity and Consistency July 11, % of farms in US experienced Drought in 2012 Corn Average Yield of Bu vs. 165 Bu per a Soy Average Yield of 35.3 Bu per a vs Bu per a 6

7 Divergent technologies are converging to address the need and opportunity in agriculture Improved Genetics Molecular Breeding Biotechnology Cell biology Improved Genetics Third wave of technology convergence 7

8 The convergence of technologies is not limited to improved genetics it extends into the value chain Robotics, Automation Sensors Improved Genetics, Chemistry, Biologicals, Nutrients IT Increased Yield, productivity, quality, Sustainability Bigger, Faster, More Intense 8

9 Opportunities for Crop Improvement No sex Nutrient content & quality Pest resistance More crop Per drop Indicators of stress; stress tolerance light response/efficiency - Duration of Photosynthesis Shelf life Nutrient response Modified from E. Pennisi Science 327, (2010) 28

10 Applications of BioDirect Technology Initial Focus Pest control Longer Term - Quality 31

11 Transforming Agriculture N-Fix Food Grade Bacteria Naturally occurring, Nitrogen fixing bacteria from sugarcane (inter-cellular) - takes up and uses Nitrogen from the air Applied to the cells of plants (intra-cellular) via the seed - provides every cell in the plant with the ability to fix Nitrogen Nitrogen fixing bacteria intracellularly into plants via the seed - replaces around 60% of plant s Nitrogen needs N-Fix is neither genetic modification (GM) nor bio-engineering Seed dressing & soil inoculant can be easily mass produced through normal fermentation 11 32

12 We are migrating from mechanization to automation Enabled by Big Data Capabilities 35

13 Venture Capital Backed Innovators The Emerging Bioeconomy Is Reshaping The Chemical Industry Increasing Convergence Of Petro/Oleo/Bio Companies To Biogreentech Innovation Addressing Demand for Green and Responding to Broad Market Drivers O&G Feedstocks & Refiners Petro-chemical Companies Market Demand Bio Feedstocks & Refiners CONVERGENCE TOWARDS INNOVATIONS IN BIOGREENTECH, NANOTECH, SUSTAINABILITY Oleo/Bio-chemical Companies Market Drivers Regulatory Trends, Price Volatility, Diminishing Natural Resources Note: Companies represented on this slide are only a subset of examples for each category 13

14 Technology at commercial scale world s first Iso Butanol Plant

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16 The Pathway for biosynthesis of rebaudiosides in Yeast Fine Chemical Production

17 Enormous Market most oil from wells is unrecovered! Biology and Oil Recovery 2/3 of 1.2 trillion bbls conventional reserves typically reserves left behind worldwide 1 2/3 of resources typically left behind 1 EIA International Energy Annual Report Unrecoverable reserves several times higher than 1.2 trillion bbls 2 $90 oil >$2 billion annual value creation from 1% market capture 2 8 billion bbls annual production from candidate reservoirs worldwide >$70 trillion value 2

18 Glori Energy is using biotechnology to harvest oil 18

19 For start ups Significant opportunities remain in agriculture: Input reduction Pest protection Yield protection Light efficiency CO2 fixation efficiency Yield genes Yield enhancement Breeding, Germplasm Cell biology Consistent Yield IT, Automation Plants as factories Differentiated Grains

20 For Start Ups Significant Opportunities in Specialty and Fine Chemicals and Enabling Platforms: Conversion of C1 and C2 substrates to innovative products with applications in food, feed, chemical and material industries Reducing fermentation time and increasing concentrations of substrates and products Nutritional, Wellness products in Human and Animal Nutrition Pest Control Agents with unique modes of action; materials with unique properties etc. 20

21 Contact: THANK YOU Merci Beaucoup Terima Kasi 21

22 Key Take Home Messages: Innovation in Bio Green technology is essential for global Nutrition, Energy and Material Security population, economic growth & climate change Green Biotechnology has enabled superior pest control still need to address the calorie needs and protein needs of seven billion plus people Securing consistent and higher yield remains an imperative for Bio Economy Developments in synthetic biology and chemistry enable the improved productivity of agriculture and forestry feedstocks and leveraging them for both fuel and chemical applications First generation of White Biotech products continue to expand; Second Generation of White Biotechnology products are addressing the issues of scale up and capital Regulations and public support is essential for the emergence of bioeconomy 22