Stephen Strom (Cell Transplantation and Regenerative Medicine, KI) Stem Cell Therapy of Liver Disease

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1 Final Programme Tuesday 13 th October Location: HERM Seminar Room, NOVUM, 4 th Floor (entrance through HERM) Welcome and Introduction to the Sessions Chair: Hong Qian (HERM, KI) Hong Qian (HERM, KI) Mesenchymal stem and progenitor cells in maintenance of normal hematopoiesis Stephen Strom (Cell Transplantation and Regenerative Medicine, KI) Stem Cell Therapy of Liver Disease Coffee Cecilia Österholm- Corbascio (MMK, KI) Immunomodulatory properties of fetal cardiac MSCs Lunch Session 2 Chair: Cecilia Götherström (HERM, KI) Cecilia Götherström (HERM, KI) Boost Brittle Bones Before Birth Paul Kingham (Department of Integrative Medical Biology, Umeå University) The biology and therapeutic potential of adipose derived stem cells for repairing damaged nerves and soft tissue defects Coffee Johan Bengzon, (Lund Stem Cell Center, Lund University Hospital) Mesenchymal Stromal Cells in Brain Tumors - function and therapeutic potential

2 Wednesday 14 th October Location: Hörsalen, NOVUM, 4 th floor Welcome and Introduction to the Sessions Chair: Lindsay Davies (HERM, KI) Stellan Hertegård (CLINTEC, KI) Regeneration of scarred vocal folds with mesenchymal stem cells. A clinical study Christian Göritz (Cell Transplantation and Regenerative Medicine, KI) The Role of Pericytes in Central Nervous System Scarring and Fibrosis Coffee Stefan Scheding (Lund Stem Cell Centre, Lund University) Isolation and characterization of primary human bone marrow mesenchymal stem cells Lunch Session 2 Chair: Katarina Le Blanc (HERM, KI) Katarina Le Blanc (HERM, KI) Bringing Mesenchymal Stem Cells into the clinic Lindsay Davies (HERM, KI) Oral progenitor cells- natural defenders of the oral cavity? Coffee Koen Schepers (Leiden University Medical Centre, The Netherlands) Understanding the role of the microenvironment in normal and diseased hematopoiesis

3 Thursday 15 th October Location: Hörsalen, NOVUM, 4 th floor Chair: Stefan Scheding (Lund Stem Cell Centre, Lund University) Welcome and Introduction to the Sessions Simón Méndez- Ferrer (Stem Cell Institute and Department of Haematology, University of Cambridge, UK) The two faces of MSCs in myeloid neoplasias Marc Raaijmakers (Department of Hematology and Erasmus Stem Cell Institute, The Netherlands) Deconstructing mesenchymal contributions to malignant transformation in the hematopoietic system Coffee Jens Kastrup (Rigshospitalet, Copenhagen, Denmark) MSC therapy an option in patients with heart failure? Elena Jones (Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, UK) Native MSCs in human bones and joints Lunch Session 2 Chair: Lindsay Davies (HERM, KI) Eva Mezey (National Institute of Dental and Craniofacial Research/NIH, Bethesda, MD, USA) Immune- suppressive properties of human BMSCs: Donor variability and possibilities for priming Sven Brandau (Department of Otorhinolaryngology, University Hospital Essen, Germany) Immunological consequences of TLR signalling in MSCs Coffee Moustapha Kassem (Endocrinology and Metabolism, University Hospital of Odense, Denmark) Targeting skeletal stem cells for enhancing bone formation

4 Hans- Jörg Bühring (Laboratory for Stem Cell Research, University Clinic of Tübingen, Germany) Markers for the prospective isolation of human bone marrow- derived MSC: identification of two functionally and phenotypically distinct subsets

5 Friday 16 th October Location: Hörsalen, NOVUM, 4 th floor Chair: Katarina Le Blanc (HERM, KI) Welcome and Introduction to the Sessions Christian Jorgensen (Department for Biotherapy at University Hospital CHU Lapeyronie University Hospital, Montpellier, France) Adipose derived stem cells for osteoarthritis: the adipoa experience Francesco Dazzi (Department of Haemato- Oncology, King s College London, UK) Host dependent mechanisms of MSC therapeutics Coffee Willem Fibbe (Leiden University Medical Center, The Netherlands) Immunoregulatory assessment of MSC therapy Mauro Krampera (Stem Cell Research Laboratory, University of Verona, Italy) Immunological assays as functional release criteria for MSCs Jacques Galipeau (Winship Cancer Institute, Emory University, Atlanta, GA, USA) Mechanistic analysis of MSCs for optimized use in clinical trials End of course wrap up

6 Instructions on how to get to Novum lecture hall and seminar rooms from Blickagången 6 or Hälsovägen 7 entrances Contact person: Lindsay Davies Mobile phone: Lili Andersson Mobile phone: Address lecture hall and seminar rooms: Monday, Tuesday = HERM seminar room, Novum 4 th floor Wednesday, Thursday, Friday = Novum Lecture Hall, 4 th Floor, Hälsovägen 7, Huddinge Thursday evening, buffet for course participants (registration required): HERM, Novum 4 th floor Instructions: By train Once you arrive at Flemingsberg, walk towards Karolinska University Hospital (Huddinge) Novum. Follow the signs. Cross the big square, on your left side there is a library. After a small bridge you are on Blickagången, the Entrance is at Blickagången 6. The NOVUM building is to your right. By car Drive from Stockholm to Novum Research Park, Hälsovägen 7. Go southwards on E4, and then turn off at Vårby (exit 148). Please follow the hospital signs to Karolinska University Hospital in Huddinge and Novum Research Park. There is guest parking outside the main entrance as well as outside Hälsovägen 7. Map

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