CEVA-PHYLAXIA. Diarsanyl. Kiire ja usaldusväärne vahend koerte ja kasside kõhulahtisuse peatamiseks

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1 CEVA-PHYLAXIA Diarsanyl Kiire ja usaldusväärne vahend koerte ja kasside kõhulahtisuse peatamiseks

2 PATOFÜSIOLOOGIA ÜKSKÕIK, mis kõhulahtisuse põhjustab, toimuvad ikka kokkuvõttes samad protsessid: muudatused mutsiinkihis enterotsüütide vigastused naaberrakkude ühenduskohtade lõhkumine basaalmembraani kahjustused seeduvuse ja imendumise häired elektrolüütide kadu toitainete kadu vedelike kadu osmootsel teel negatiivne energiatasakaal sügavamate kudede kaasamine: põletik ja nakkused 2

3 RAVI Dieet Limaskesta kaitse Kahjulike ainete sidumine ja eemaldamine Vedeliku, happe-aluse, energia ja elektrolüütide tasakaalu stabiliseerimine Põhjuslik ravi - siseparasiitide tõrje - antibiootikumid Muud - analgeesia - spasmolüütikumid - tugevdavad ravimid 3

4 LIMASKESTA KAITSE Eesmärk limaskesta kaitsmine - mutsiini viskoossuse taastamine - mukolüüsi peatamine - mutsiiniproduktsiooni stimuleerimine - limaskesta edasise hävitamise peatamine Savimineraalid: montmorilloniit, kaoliin jne. Iseloomustav omadus: aktiivse välispinna suurus Külső aktív felület Aktiivne välispind m 2 /gramm Montmorilloniit Montmorillonit 82 Kaolin Kaoliin 22 Dupuis, C.: Les argiles en thérapeutique digestive Thése D. Pharm, Université de Poitiers,

5 ADSORBENDID Eesmärk: kahjulike ainete sidumine ja Savimineraalid eemaldamine Iseloomustavad omadused: - aktiivse sisepinna suurus katioonivahetuse võime - lamellidevahelise pinna suurus - kihtide arv Kihtide Rétegek arvszáma Montmorilloniit Montmorillonit 3 Kaoliin Kaolin 2 Belső Aktiivne aktív sisepind felület m 2 /gramm Montmorilloniit Montmorillonit 660 Kaoliin Kaolin 45 Kationcserélő képesség Katioonivahetuse võime me / 100g Montmorilloniit Montmorillonit 60 Kaoliin Kaolin 5 Lamellidevaheline Interlamelláris tér pind Å* Montmorilloniit Montmorillonit 14 Kaoliin Kaolin 7 * 1Å = m Dupuis, C.: Les argiles en thérapeutique digestive Thése D. Pharm, Université de Poitiers,

6 HOMEOSTAASI TAASTAMINE Vedeliku, happe-aluse, energia ja elektrolüütide tasakaalu stabiliseerimine - elektrolüütide kaotamine seedevedelikega Na +, K +, Cl - - energia kaotamine seedumatuse ja imendumishäirete tõttu näit. dekstroos* * Vajame kiiresti toimiva, kuid organismi mitte ülekoormava energia allikat (osmootne kõhulahtisus) 6

7 Diarsanyl -i koostis montmorilloniit Na +, K + dekstroos Pasta on maitsestatud viskoosne lihtsalt kasutatavas süstlas 7

8 MONTMORILLONIIT On tõestatud, et montmorilloniit on võrreldes paljude teistega parem limaskesta kaitsevahend ja adsorbent Dupuis, C.: Les argiles en thérapeutique digestive Thése D. Pharm, Université de Poitiers, 1996 vähendab mukolüüsi takistab limaskesta hävimist toimib bakterite sissetungi vastu suurendab vee ja elektrolüütide adsorptsiooni Rateau, J.G. et al: A histological, enzymatic and water-electrolyte study of the action of smectite, a mucoprotective clay, on experimental infectious diarrhoea in the rabbit. Curr. Med. Res. Opin., Vol. 8, No4, (1982) aitab kaasa seedetrakti motoorikale Fioramonti, J., Droy-Lefaix, M. T. and Bueno, L.: Changes in gastrointestinal motility induced by cholera toxin and experimental osmotic diarrhea in dogs. Effects of treatment with an argillaceous compound. Digestion 36: (1987) suurendab limaskesta resistentsust Droy, M.T. et al.: La filiance: nouvelle approche de l aggression intestinale et de sa thérapeutique. Gastroent. Clin. Biol. 9: (1985) 8

9 Annustamine koertele ja kassidele diarsanyl paste should generally be given for 3 days Diarsanyl i pastat antakse reeglina 3 päeva järjest For Looma animals kaal weighing Üks One ab of the mõõtevahemik injector delivers sisaldab Annus (mõõtevahemike ( arv) ) Hommik Õhtu Number 3-päevaseks of injectors raviks requiredvajalik for a 3- süstalde days treatment arv Diarsanyl10ml 2-7 kg 1ml kg kg Diarsanyl24ml kg 2ml 3 3 1, kg Above50 Üle kg kg 5 5 2,5 9

10 TEISED LOOMALIIGID Tuhkur Küülik Merisiga Rott Taimetoiduline roomaja Lihatoiduline roomaja Hobune Poni Varss Vasikas Lammas Kits Põrsas 2 x 1 ml 2 x 0,5 1 ml 2 x 0,5 1 ml 2 x 0,5 1 ml 2 x 0,1 0,2 ml 2 x 0,2 0,3 ml 2 x 30 ml 2 x 10 ml 2 x 10 ml 2 x 10 ml 2 x 10 ml 2 x 10 ml 2 x 4 10 ml 10

11 -i EDU KOLM PÕHJUST Sobiv koostis kahjulike ainete sidumine ja eemaldamine limaskesta kaitse ja mutsiinikihi regeneratsioon elektrolüütide ja energia kao kompenseerimine Optimaalne viskoossus homogeenne kaitsekiht Lihtne kasutada maitsestatud pasta 10 ml ja 24 ml praktiline süstal 11

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