DAS FRAUNHOFER IKTS ALS INNOVATIVER PARTNER IM BEREICH BIO- UND MEDIZINTECHNIK

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1 DAS FRAUNHOFER IKTS ALS INNOVATIVER PARTNER IM BEREICH BIO- UND MEDIZINTECHNIK Andreas Lehmann, Dr. rer. nat. Jörg Opitz Medizintechnik in Sachsen

2 Our Business Divisions Fraunhofer IKTS in profile MATERIALS AND PROCESSES SYSTEMS EXPERTISE ENVIRONMENTAL AND PROCESS ENGINEERING MECHANICAL AND AUTOMOTIVE ENGINEERING ELECTRONICS AND MICROSYSTEMS MATERIALS DIAGNOSTICS Reliability Quality assurance BIO- AND MEDICAL TECHNOLOGY OPTICS ENERGY TECHNOLOG Y EXPERTISE WERKSTOFF- KOMPETENZ MATERIALS AND PROCESS ANALYSIS

3 Fraunhofer IKTS - BioMed Business Division Bio- and Medical Technology Competencies Development, processing and integration of biomaterials Shaping and surface technologies Microsystems technology Sensors and actuators Integration of functional mechatronic components (Bio)medical analytics and diagnostics Applications Dental technology Implants/endoprosthetics Instruments Medical components Biosensors and actuators Analytics and diagnostics

4 BioMed - competencies Competencies Biomaterials Development of customized biomaterials with defined property and structural parameters Material groups Oxide ceramics as a high purity dense or porous bioceramicsbased on Al 2 O 3 andzro 2 (ATZ, ZTA, Y-TZP, Ca 3 (PO 4 ) 2 ) andhap ceramic(lithium) Foam ceramic and metal foams Oxide and non-oxide ceramics with specific electrical, thermal and mechanical features Polymer ceramics and composites Individual material development DIN EN ISO 9001:2008 und EN ISO Scale-Up to the preindustrial scale

5 BioMed - competencies Competencies Sensor and actuator Development of functional materials, miniaturized components and systems Ceramic micro system technology(htcc, LTCC) Thick film (screen, template, pad printing) Thin film technology(cvd, PECVD, ALD) Direct writing method (aerosol, inkjet) Biocompatible assembly and packaging technology Housing und Interfaces Functional components (di-, piezo and ferroelectrics) Linking structural and functional ceramics Application centres for technology testing

6 BioMed - competencies Competencies Characterization Monitoring & testing and diagnostic methods Complex material characterization on nano, micro and macro levels (TEM, SEM, AFM, AFAM) Biophysical characterization body and surfaces Development of in vivo and in vitro analysis systems and diagnostic systems CellTissueMonitoring Investigation of stimulation and suppression processes Fluorescence-based tumor diagnosis Quality assurance of production processes (inline und post mortem) Fraunhofer IKTS branch materials diagnostics Service and method development

7 BioMed - applications Applications Implants Material development Biofunctional and biomimetic ceramics Oxid ceramicbasedon Al 2 O 3 andzro 2 High purity dense or porous Al 2 O 3 bioceramicswith sub-µm/nano-structures for shaped implants Foam ceramics and metal foams for bone replacement material Technology development Foaming-and molding technologies, slip casting, sol-gel and plasma coating, generative techniques Bioceramicsurface and shape body design Knee endoprosthesis

8 BioMed - applications Applications Dental ceramics Customer-specific material development Oxid ceramicbasedon Al 2 O 3, ZrO 2 andtheirdispersions with finely dispersed microstructure and high strength ceramicmaterialsbasedon Li 2 Si 2 O 5 Efficient process development Slip casting of ceramic components with complex geometries Closed CAD / CAM process chain certified EN ISO 13485: AC:2009 3D digitizer Dental ceramics under UV illumination SEM image Y-TZP

9 BioMed - applications Applications Biosensors and -actors Sensors for diagnostics Multisensor-Arrays CellTissueMonitoring Development of nanoparticles for diagnostics Bioactors Functional stimulation module (electric / acoustic / mechano-stimulation in vitro and in vivo) Ultrasonic transducer arrays for particle manipulation Ultrasonic transducer arrays for particle manipulation Energy systems Scalable power transmission systems ex-vivo to in vivo (eg. for theranostical hip implants) Mobile power transmission system

10 BioMed - applications Applications Monitoring systems / testing and diagnostic systems Process development Qualification optical diagnostics for medical and life sciences (OCT, Nanoraman) Monitoring of cell and bacterial growth processes Sensors for the detection of biogenic and biosynthetic polymers Intraocular pressure measurement using air-ultrasound Sterility detection by nanoparticles(sterihealth ) Device development Fluorescence-basedcancerdiagnostic(OCD) 3D visualization of a tooth using optical coherence tomography

11 BioMed - applications Applications Surgical instruments and components Materials, technology and component developments (Micro) Surgical instruments and cutting materials Ceramic tips for minimally invasive surgery Functional (conductive, bioactive, biosuppressive) layers Functional films Ceramic springs Components for X-ray equipment Plasma gel-coated surgical instrument

12 THANK YOU FOR YOUR ATTENTION! Contact: Andreas Lehmann Fraunhofer IKTS Maria-Reiche-Str Dresden andreas.lehmann@ikts.fraunhofer.de

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