The European Medical Technology Industry. in figures / 2018
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1 The European Medical Technology Industry in figures / 2018
2 Table of contents What is Medical Technology? 4 Innovation 10 Employment 14 Companies 18
3 Expenditure on Medical Technology 20 MedTech Market in Europe 24 Trade in Europe 32 About MedTech Europe 38
4 What is Medical Technology?
5 Medical technology is any technology used to save lives or transform the health of individuals suffering from a wide range of conditions. In its many forms, medical technology is already diagnosing, monitoring and treating virtually every disease or condition that affects us. For the sake of this document, medical technology includes medical devices and in vitro diagnostic medical devices. Medical devices are products intended to perform a therapeutic or diagnostic action on human beings by physical means. In vitro diagnostic medical devices are products which provide medically useful diagnostic information by examination of a specimen derived from the human body. What is Medical Technology? 5
6 There are more than 500,000 medical technologies currently available and they all share a common purpose: improving, extending and transforming people s lives. Medical technology can be familiar, everyday products such as blood glucose meters, sticking plasters, syringes or latex gloves. Alternatively, it can also be pregnancy tests, spectacles, wheelchairs and hearing aids. Meanwhile, Visual 1: at Diversity the high-tech and end classification of the scale, medical of medical technology technology includes molecular diagnostics, total Medical body scanners, Devices ultrasounds, life-supporting machines, implantable devices such as heart valves In Vitro and pacemakers, Diagnostics neurostimulators and replacement joints for knees and hips. The common thread through all applications of medical technology is the beneficial impact on health, quality of life and in society as a whole. Medical technologies contribute to living longer and better, and empower citizens to contribute to society for longer. In so doing, they improve the quality of care and the efficacy, efficiency and sustainability of healthcare systems. 6 What is Medical Technology?
7 Regulation and classification of medical technologies In the European Union, medical technologies are tightly regulated by laws that govern the safety and performance of devices across their lifetime, pre- and post-market. Over the next few years, the European medical technology sector will transition from being regulated under the current medical devices directives to two new regulations. What is Medical Technology? 7
8 Classification of in vitro diagnostic medical devices Today, the in vitro diagnostic (IVD) sector is regulated by Directive 98/79/EC. From 26 May 2022, the new Regulation 2017/746/EU will fully apply. Until this date, manufacturers can choose to comply with either the Directive or the Regulation. Classification of IVDs is important as it determines the level of involvement by a third party (the notified body ) in assessing IVDs both pre- and post-market. This level of control is generally relative to the risk of an erroneous result from the assay. Under the IVD Directive, IVDs are classified into four classes following a positive list approach: Annex II List A Annex II List B Devices for self-testing Self-declared devices (e.g. ABO bloodtyping) (e.g. blood glucose monitoring) (e.g. pregnancy tests) (e.g. clinical chemistry analyser) Under the IVD Regulation, all IVDs will be classified under a new risk-based classification system according to the risk the device poses to the health of the public and or an individual as result of an incorrect test result. All IVDs will be classified under class A, B, C or D, with class D being the highest risk class. 8 What is Medical Technology?
9 Classification of medical devices The medical device (MD) sector is regulated by Directives 93/42/EC and 90/385/EEC. From 26 May 2020, the new Regulation 2017/745/EU will fully apply. Until this date, manufacturers can choose to comply with either the Directives or the Regulation. Classification of medical devices (estimated to be more than ) drives many pre- and postmarket requirements. Due to the large variety of products, the level of control made by a thirdparty (the notified body ) before placing them in the market depends on the level of impact on the human body that their use might imply. The same notified body is involved post-market to ensure the continued safety and performance of medical devices. Under the MD Directive, MDs are classified into 4 classes following a risk based classification system: Class I Class IIa Class IIb Class III (e.g. simple bandages or wound care products) (e.g. syringes without the needle) (e.g. anaesthesia machines) (e.g. pacemakers) Under the new MD Regulation, the risk-based classification system contained in the current Directives has been maintained, although some changes/additions have been introduced. The principle is the same: to link the class of the device to the potential risk posed to the health of the public and an individual as result of fault in the functioning. All MDs are classified under class I, IIA, IIB or III, with class III being the highest risk class. What is Medical Technology? 9
10 Innovation
11 Medical technology is characterised by a constant flow of innovation, which is the result of a high level of research and development within the industry, and of close co-operation with the users. Products typically have a lifecycle of only months before an improved product becomes available. In 2016, more than 12,200 patent applications were filed with the European Patent Office (EPO) in the field of medical technology 7.7% of the total number of applications, still more than any other sector in Europe. 41% of these patent applications were filed from European countries (EU28, Norway and Switzerland) and 59% from other countries, out of which with the majority of applications filed from the US (38%). In comparison, around 5,700 applications were filed in the pharmaceutical field and around 5,700 also in the field of biotechnology. While over the last decade the number of EPO filings in the field of medical technology has doubled, pharma and biotech patent applications were relatively stagnant 1. PATENT APPLICATION IN MEDICAL TECHNOLOGY FIELD FILLED WITH EPO IN % EU28, Norway and Switzerland 59% Other countries Innovation 11
12 TOP 10 TECHNICAL FIELDS IN PATENT APPLICATIONS. NUMBER OF PATENT APPLICATIONS FILED WITH EPO, 2016 (REF. 1) 12,263 MEDICAL TECHNOLOGY 10,915 10,657 DIGITAL COMMUNICATION COMPUTER TECHNOLOGY 10,293 ELECTRICAL MACHINERY, APPARATUS, ENERGY 8,402 7,442 6,301 TRANSPORT MEASUREMENT ENGINES, PUMPS, TURBINES 6,189 5,754 5,744 ORGANIC FINE CHEMISTRY PHARMACEUTICALS BIOTECHNOLOGY
13 EVOLUTION OF EUROPEAN PATENT APPLICATIONS BY TECHNICAL FIELD (REF. 1) Medical technology Biotechnology Pharmaceuticals Innovation 13
14 Employment
15 >675,000 3 employees The European medical technology industry employs directly more than 675,000 people. Germany had the highest absolute number of people employed in the medical technology sector, while the number of medtech employees per capita is highest in Ireland and Switzerland. This high level of employment shows that the medical technology industry is an important player in the European economy. In comparison, the European pharmaceutical industry employs more than 740,000 people 2. Europe refers to EU 28, Norway and Switzerland unless specified otherwise. Employment 15
16 TOP 7 COUNTRIES WITH HIGHEST EMPLOYMENT IN THE MEDICAL TECHNOLOGY INDUSTRY (REF. 3) United Kingdom 100,000 Germany 210,000 Ireland 35,000 Switzerland 54,000 France 85,000 Spain 23,000 Italy 38, MedTech Market in Europe
17 NUMBER OF PEOPLE DIRECTLY EMPLOYED IN THE MEDICAL TECHNOLOGY INDUSTRY PER 10,000 INHABITANTS IN 2016 (REF. 3) Ireland 74 Switzerland 64 Denmark 26 Germany 25 Sweden 23 Belgium 15 UK 15 France 13 Italy 13 Netherlands 9 Spain 5 Greece 5 Portugal 4 Employment 17
18 Companies
19 27,000 medical technology companies in Europe 95% SMEs There are approximately 27,000 medical technology companies in Europe. Most of them are based in Germany, followed by the UK, Italy, Switzerland, France and Spain. Small and medium-sized companies (SMEs*) make up almost 95% of the medical technology industry, the majority of which employ less than 50 people (small and micro-sized companies) 3. *An enterprise is considered to be a SME if it employs fewer than 250 persons and has an annual turnover not exceeding 50 million (small company- employs fewer than 50 persons and has a turnover of less than 10 million). Companies 19
20 Expenditure on Medical Technology
21 203 Expenditure on medical technology per capita in Europe In Europe, an average of 10% of gross domestic product (GDP) is spent on healthcare. Of this figure, around 7.2% is attributed to medical technologies, i.e. less than 1% of GDP. The spending on medical technology is estimated to vary significantly across European countries, ranging from around 5% to 10% of the total healthcare expenditure 4. Expenditure on medical technology per capita in Europe is at around 203 (weighted average). Expenditure on Medical Technology 21
22 BREAKDOWN OF TOTAL HEALTHCARE EXPENDITURE IN EUROPE (REF. 5) 7.2% Medical technology 0.7% In vitro diagnostics 15.9% Phamaceuticals & other medical non-durables 6.5% Medical devices (incl. imaging) 76.9% Inpatient & outpatient care, other 22 Expenditure on Medical Technology
23 Expenditure on Medical Technology 23
24 MedTech Market in Europe
25 110 billion market The European medical technology market in 2016 is estimated at roughly 110 billion 6. Based upon manufacturer prices the European medical technology market is estimated to make up 29% of the world market. It is the second largest medical technology market after the US (approximately 43%). MedTech Market in Europe 25
26 EUROPEAN MEDICAL DEVICE MARKET BY COUNTRY, BASED UPON MANUFACTURER PRICES, 2016 (REF. 6) GERMANY 28 % FRANCE 15 % UK 12 % ITALY 10 % SPAIN 6 % NETHERLANDS 4 % SWITZERLAND 4 % BELGIUM 3 % SWEDEN 2 % AUSTRIA 2 % OTHER 14 % 26 MedTech Market in Europe The biggest medtech markets in Europe are Germany, France, the United Kingdom, Italy and Spain 6. The same countries form the top 5 IVD markets in Europe 7.
27 EUROPEAN IVD MARKET BY COUNTRY, 2016 (REF. 7) GERMANY 21 % ITALY 15 % FRANCE 13 % SPAIN 9 % UK 9 % SWITZERLAND 4 % BELGIUM 3 % NETHERLANDS 3 % POLAND 3 % AUSTRIA 2 % OTHERS 17 % MedTech Market in Europe 27
28 WORLD MEDICAL DEVICE MARKET BY REGION BASED UPON MANUFACTURER PRICES, 2016 (REF. 6) USA EUROPE JAPAN CHINA 43 % 29 % 7 % 6 % CANADA BRAZIL RUSSIA OTHER 2 % 1 % 1 % 11 % 28 MedTech Market in Europe
29 WORLD MEDICAL TECHNOLOGY MARKET BY AREA AND SALES GROWTH, (REF. 8) WW Market Share in % 16% 14% 12% 10% 8% 6% 4% 2% 0% Diagnostic imaging Orthopedics Wound management Cardiology Ophthalmics Drug delivery General & Plastic Surgery Dental In Vitro Diagnostics (IVD) Endoscopy +3.0% +3.5% +4.0% +4.5% +5.0% +5.5% +6.0% +6.5% +7.0% Source: Evaluate, September 2017 % Sales Growth: CAGR Medical technology offers solutions for many disease areas. On a worldwide perspective, in vitro diagnostics are the largest sector, followed by cardiology and diagnostic imaging 8. Note: Size of Bubble = WW Sales in 2022 MedTech Market in Europe 29
30 EUROPEAN MEDICAL DEVICE MARKET GROWTH RATES, BASED UPON MANUFACTURER PRICES, (REF. 6) 15% 10% 5% 0% % The European medical technology market has been growing on average by 4,4% per annum over the past 9 years. Demand fell in 2009 due to the economic crisis, resulting in a growth rate of only 1%. The market recovered in 2010, but growth rates fell back in MedTech Market in Europe
31 EUROPEAN IN VITRO DIAGNOSTICS MARKET GROWTH RATES, BASED UPON MANUFACTURER PRICES, (REF. 7) 5% 4% 3% 2% 1% 0% % -2% -3% -4% The European IVD market growth has been slowing down until 2013, while annual growth rates in the pre-crisis period were at around 2-4%. In 2013 the European market started to recover and the annual growth rate in 2016 was around 1%. * Market size estimated in manufacturers prices, not including margins, such as value added in the wholesaling and retailing, transportation costs, some taxes included in the final price, etc. MedTech Market in Europe 31
32 Trade in Europe
33 17.5 billion Estimation of Europe s trade surplus in 2016 Europe has a positive medical technology trade* balance of 17.5 billion (2016) and this represents a more than twofold increase since In comparison, the US medical technology trade surplus is at 5 billion. Compared to 2012, the main European medtech trade partners remain the same: the US, China and Japan (Ref 6). *Trade section does not include in vitro diagnostics in the figures for medical technology. Trade in Europe 33
34 TOP EUROPEAN MEDICAL DEVICE EXPORT DESTINATIONS, 2016 (REF. 6) Russia 2.8% USA 36.9% China 10.3% Japan 5.4% India 1.9% Brazil 1.4% 34 Trade in Europe
35 TOP SUPPLIERS TO EUROPEAN MEDICAL DEVICE MARKET (IMPORTS), 2016 (REF. 6) Canada 3.0% USA 55.0% India 0,8% Singapore 2.0% China 10.0% Japan 5.0% Australia 4.0% Trade in Europe 35
36 EXPORT AND IMPORTS OF MEDICAL DEVICE BY COUNTRY 2016 (INCLUDING INTRA-COMMUNITY TRADE, MILLION EUROS) (REF. 6) MILLIONS GERMANY NETHERLANDS BELGIUM IRELAND SWITZERLAND FRANCE UNITED KINGDOM ITALY AUSTRIA DENMARK FINLAND SPAIN SWEDEN POLAND CZECH REPUBLIC 36 Trade in Europe
37 MEDICAL DEVICE TRADE BALANCE BY COUNTRY (INCLUDING INTRA-COMMUNITY TRADE, MILLION EUROS), 2016 (REF. 6) MILLIONS % IRELAND GERMANY SWITZERLAND NETHERLANDS BELGIUM FINLAND DENMARK HUNGARY AUSTRIA CZECH REPUBLIC LITHUANIA 46 ESTONIA LATVIA -61 BULGARIA SLOVENIA SWEDEN CROATIA SLOVAKIA ROMANIA POLAND PORTUGAL GREECE NORWAY -604 ITALY UK SPAIN FRANCE Trade in Europe 37
38 About MedTech Europe
39 MedTech Europe is the European trade association representing the medical technology industry from diagnosis to cure. We represent In-Vitro Diagnostics and Medical Devices manufacturers operating in Europe. MedTech Europe s mission is to make innovative medical technology available to more people, while helping healthcare systems move towards a sustainable path. MedTech Europe promotes a balanced policy environment that helps the medical technology industry meet Europe s growing healthcare needs and expectations. We also promote medical technology s value for Europe through our five-year industry strategy, which focuses on valuebased innovations that support more sustainable healthcare systems. We use economic research to show the benefits of medical technology and we organise many initiatives to explain the value we bring to Europe. We bring stakeholders together to discuss trends, issues and opportunities. Each year we also organise the European MedTech Forum, the largest health and industry policy conference in Europe, to engage with stakeholders on common topics of interest. About MedTech Europe 39
40 References 1 European Patent Office, MedTech Europe calculations. Medical technology as defined by World Intellectual Property Organization (based on the WIPO IPC-Technology concordance as revised in August 2014). European countries refer to EU + Norway, Switzerland. Patents are attributed by the country of residence of the applicant. 2 EFPIA The Pharmaceutical Industry in Figures. Key Data Europe refers to EU + Norway, Switzerland. 3 MedTech Europe calculation based on the data obtained from National Associations of 12 countries for the latest year available. Europe refers to EU + Norway, Switzerland. 4 WHO Global Health expenditure Database, Eurostat, BMI Research, MedTech Europe calculations based on the data obtained from National Associations of 15 countries for the latest year available. 5 BMI Research, WHO, Eurostat, EFPIA, EDMA, MedTech Europe calculations. Europe refers to EU + Norway, Switzerland. 6 BMI Research, MedTech Europe calculations. Manufacturer prices. Medical technology excluding in vitro diagnostics. 7 MedTech Europe - European IVD Market Statistics Report Worldwide Medtech Sales by EvaluateMedTech Device Area: Top 15 Categories & Total Market (2016 & 2022)-
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42 MedTech Europe, 2017
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The European Medical Technology Industry in figures
The European Medical Technology Industry in figures Table of contents What is Medical Technology? 4 Innovation 10 Employment 14 Companies 18 Expenditure on Medical Technology 20 MedTech Market in Europe
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