For order enquiries. Telephone Fax For technical information

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1 Sanquin is responsible for safe and efficient blood supply in the Netherlands on a not-for-profit basis. Sanquin also develops and produces pharmaceutical products, conducts high-quality scientific research, and develops and performs a multitude of diagnostic services. Continuous research and innovation lead to new and improved products and services. Quality and development therefore go hand in hand. Sanquin Divisions Blood Bank Diagnostic Services Plasma Products Research Reagents Sanquin Division Reagents Plesmanlaan CX Amsterdam P.O. Box AD Amsterdam The Netherlands For order enquiries Telephone Fax reagentsorders@sanquin.nl For technical information Telephone reagents@sanquin.nl 2016/7

2 Product list 2016 BLOOD GROUP SEROLOGY

3 2 CELLBIND GEL CARDS Cellbind gel cards article number article name package description K7000 Cellbind Screen 48 cards Universal Cellbind gel card for all blood group serology tests, including typing for blood group antigens, reverse typing, antibody screening, antibody identification, crossmatch and DAT. Each column contains anti-igm, anti-igg and anti-c3d. K7011 Cellbind Direct 48 cards Cellbind gel card for the identification of the reaction subtype in samples with a positive DAT. Two columns with anti-igg, two columns with anti-c3d and two columns for negative controls. K7012 Cellbind Direct Type 48 cards Cellbind gel card for ABO, Rhesus phenotyping and Kell typing of samples with a positive DAT. Each column contains anti-igm.

4 Blood group serology 3 Cellbind gel cards, as easy as can be Reagents for use in Cellbind gel cards ABO article number article name package clone method K11883 Pelikloon anti-a 3x10mL BIRMA1 No incubation K Pelikloon anti-a 10x10mL BIRMA1 No incubation K11893 Pelikloon anti-b 3x10mL LB2 No incubation K Pelikloon anti-b 10x10mL LB2 No incubation K11903 Pelikloon anti-a,b 3x10mL ES4 ES15 K Pelikloon anti-a,b 10x10mL ES4 ES15 No incubation No incubation

5 4 Reagents for use in Cellbind gel card Rhesus article number article name package clone method K1255 Pelikloon anti-d 10mL RUM-1 No incubation K Pelikloon anti-d 10x10mL RUM-1 No incubation K1151 Pelikloon anti-d enhanced 10mL LDM1 ESD1M No incubation One phase reagent for detection of (weak) D positive and D variant red blood cells K1157* Pelikloon anti-d mix 10mL TH28 MS26 K115710* Pelikloon anti-d mix 10x10mL TH28 MS26 Combination of incubation and no incubation Combination of incubation and no incubation K1195 Pelikloon anti-c 5mL MS24 No incubation K1196 Pelikloon anti-c 5mL MS33 No incubation K1191 Pelikloon anti-e 5mL MS260 No incubation K1197 Pelikloon anti-e 5mL MS62 MS69 K1113* Pelikloon anti-cde 10mL MS24 MS201 MS80 MS26 No incubation Combination of incubation and no incubation Rhesus second line article number article name package clone method K1202 Pelikloon anti-c 5mL MS273 No incubation K1203 Pelikloon anti-c 5mL MS35 No incubation K1204 Pelikloon anti-e 5mL MS80 MS258 K1205 Pelikloon anti-e 5mL MS21 MS63 No incubation No incubation Rare antigens article number article name package clone method K1199 Pelikloon anti-k 5mL MS56 No incubation K1236 Anti-Fy a 3mL P3TIM Incubation * K1157, K and K1113 Two phase reagent: Direct agglutination of (weak) D positive red blood cells (IgM) Indirect agglutination of weak D and D variant red blood cells (IgG)

6 Blood group serology 5 Reagents red cells for use in Cellbind gel card ABO (0.5% suspension) article number article name package description K7240 Cellbind A 1 reagent red cells 10mL Confirmation of ABO groups K7241 Cellbind A 2 reagent red cells 10mL Control cells K7242 Cellbind B reagent red cells 10mL Confirmation of ABO groups K7243 Cellbind O, D-positive reagent red cells 10mL Control cells Screening and identification (0.5% suspension) Donors are blood group O article number article name package description K7200 Cellbind P2 2x10mL For the detection of antibodies K7210 Cellbind P3 3x10mL For the detection of antibodies K7211 Cellbind P3-P 3x10mL Papain treated cells, for the detection of antibodies K7230 Cellbind ID16 16x3mL For the identification of antibodies K7231 Cellbind ID16-P 16x3mL Papain treated cells, for the identification of antibodies Cellbind LISS For preparation of 0.5% red blood cells article number article name package description K7100 Cellbind LISS 250mL For diluting cells intended for typing DAT, crosmatch and autocontrol K7110 Cellbind LISS 100mL For diluting cells intended for typing DAT, crosmatch and autocontrol K7130 Cellbind LISS 3x25mL For diluting cells intended for typing DAT, crosmatch and autocontrol K7180 Cellbind DILUENT 100mL For diluting cells intended for reverse typing, screening and identification

7 6 CELLBIND EQUIPMENT Magister C24, the perfect solution for safe, accurate and efficient blood group analysis in low throughput labs Manual article number article name description K7300 Cellbind dispenser For the addition of Cellbind LISS K7302 Cellbind centrifuge (without rotor) For 24 Cellbind gel cards K7303 Cellbind rotor K7304 Cellbind incubator For 48 cards at 37 C K7315 Cellbind workstation - Donors Holder for donor tubes K7316 Cellbind workstation - Samples Holder for sample tubes K7317 Cellbind workstation - Gelcards Holder for Cellbind gel cards

8 Blood group serology 7 Semi-Automated article number article name description K7309 Cellbind reader Cyclops-6 SA, stand alone reader for reading of Cellbind gel cards Fully Automated article number article name description K7320 Magister C24 Fully automated blood group serology system for Cellbind gel cards

9 8 REAGENTS FOR BLOOD GROUP TYPING ABO article number article name package clone method slide tube MTP Cellbind K11883 Pelikloon anti-a 3x10mL BIRMA1 Direct K Pelikloon anti-a 10x10mL BIRMA1 Direct K11893 Pelikloon anti-b 3x10mL LB2 Direct K Pelikloon anti-b 10x10mL LB2 Direct K11903 Pelikloon anti-a,b 3x10mL ES4 ES15 K Pelikloon anti-a,b 10x10mL ES4 ES15 Direct Direct

10 Blood group serology 9 Lectines article number article name package clone method slide tube MTP Cellbind K1328 K1327 Anti-A 1 (lectin) Dolichos biflorus Anti-H (lectin) Ulex europaeus 5mL Direct 3mL Direct

11 10 Rhesus article number article name package clone method slide tube MTP Cellbind K1255 Pelikloon anti-d 10mL RUM-1 Direct K Pelikloon anti-d 10x10mL RUM-1 Direct K1151 Pelikloon anti-d enhanced 10mL LDM1 ESD1M Direct One phase reagent for detection of (weak) D positive and D variant red blood cells K1157* Pelikloon anti-d mix K115710* Pelikloon anti-d mix 10mL 10x10mL TH28 MS26 TH28 MS26 Direct & indirect Direct & indirect ** ** K1195 Pelikloon anti-c 5mL MS24 Direct K1196 Pelikloon anti-c 5mL MS33 Direct K1191 Pelikloon anti-e 5mL MS260 Direct K1197 Pelikloon anti-e 5mL MS62 MS69 Direct K1201 Pelikloon anti-c w 2mL MS110 Direct K1113* Pelikloon anti-cde 10mL MS24 MS201 MS80 MS26 Direct & indirect ** Rhesus second line article number article name package clone method slide tube MTP Cellbind K1202 Pelikloon anti-c 5mL MS273 Direct K1203 Pelikloon anti-c 5mL MS35 Direct K1204 Pelikloon anti-e 5mL MS80/258 Direct K1205 Pelikloon anti-e 5mL MS21/63 Direct * K1157, K and K1113 Two phase reagent: Direct agglutination of (weak) D positive red blood cells (IgM) Indirect agglutination of weak D and D variant red blood cells (IgG)

12 Blood group serology 11 Rare antigens article number article name package clone method slide tube MTP Cellbind K1199 Pelikloon anti-k 5mL MS56 Direct K1300 Pelikloon anti-jk a 2mL MS15 Direct K1301 Pelikloon anti-jk b 2mL MS8 Direct K1302 Pelikloon anti-m 2mL LM110 LM140 Direct K1313 Pelikloon anti-n 2mL BO3 Direct K1304 Pelikloon anti-s 2mL MS94 Direct K1305 Pelikloon anti-p 1 2mL P3NIL100 Direct K1306 Pelikloon anti-le a 2mL LEA2 Direct K1317 Pelikloon anti-le b 2mL P3F234MD4 Direct K1310 Pelikloon anti-k (Cellano) 2mL Lk1 Direct K1236 Anti-Fy a 3mL P3TIM Indirect ** K1337 Anti-Fy b 3mL Indirect K1334 Anti-Kp a 3mL Indirect K1335 Anti-Kp b 3mL Indirect K1340 Anti-Lu a 3mL Indirect K1343 Anti-s 3mL Indirect K1344 Anti-Wr a 3mL Indirect Controls article number article name package description K1156 Pelikloon control monoclonal 10mL Control on false-positive results with monoclonal blood grouping reagents K1146 AB serum (pooled) 10mL Control on false-positive results with polyclonal blood grouping reagents K1152 Pelikloon enhanced control 10mL Control for K1301 Pelikloon anti-jk b ** K1157, K115710, K1113 and K1236 can only be used in Cellbind Screen (K7000) and not in Cellbind Direct Type (K7012)

13 12 ANTI-HUMAN GLOBULIN (COOMBS SERA) AHG contains anti-human IgG antibodies and/or anti-complement antibodies and can be used for the (in)direct antiglobulin test. All AHG (Coombs sera) are suitable for the tube technique. Monospecific article number article name package clone method K1131 Monospecific anti-human IgG 10mL IAT (LISS or PEG) DAT K1124 Monospecific anti-human IgG (green) 10mL K1377 Pelikloon anti-human C3d 5mL BRIC8 DAT K1378 Pelikloon anti-human C3c, C3d 5mL C3-14/BRIC8 DAT K1375 Monospecific anti-human IgA 5mL DAT K1376 Monospecific anti-human IgM 5mL DAT IAT (LISS or PEG) DAT

14 Blood group serology 13 Polyspecific article number article name package clone method K1193 K1194 Pelikloon polyspecific anti-human serum Pelikloon polyspecific anti-human serum (green) 10mL BRIC8 IAT (LISS or BSA) DAT 10mL BRIC8 IAT (LISS or BSA) DAT

15 14 POTENTIATING REAGENTS All potentiating reagents are suitable for use in the tube technique. Bovine Serum Albumin article number article name package method K1106 BSA 22% 10mL BSA-IAT K1107 BSA 30% 10mL BSA-IAT Polyethylene Glycol article number article name package method K1159 PEG % 20mL PEG-IAT

16 Blood group serology 15 Low Ionic Strength Solution article number article name package method K1110 PeliLISS 10mL LISS-IAT Enzyme article number article name package method K1121 Bromelin (lyophilised) 5mL enzyme test

17 16 REAGENT RED CELLS Characteristics Identification panels always include a Kpa, Lua and Wra positive cell, a k negative cell and a RzR2 cell The panels always contain Cw positive cells and the 3 cell screening panels are Bga, Bgb and Bgc negative All characteristics, such as unique rare antigens and mutations, are reported if known. Produced every 4 weeks

18 Blood group serology 17 ABO (3% cell suspension) article number article name package description K1140 A 1 reagent red cells 10mL Confirmation of ABO groups K1141 A 2 reagent red cells 10mL Control cells K1142 B reagent red cells 10mL Confirmation of ABO groups K1143 O, D-positive reagent red cells 10mL Control cells K1144 O, D-negative reagent red cells 10mL Control cells Coombs (3% cell suspension) Donors are blood group O/D positive. The red blood cells are sensitised with IgG anti-d antibodies. article number article name package description K1138 Coombs Control Cells strong 10mL Control cells K1145 Coombs Control Cells 10mL Control cells Screening Donors are blood group O article number article name package description K1388 Screening set 1+2 2x10mL For the detection of antibodies (3%) K1148 Screening panel 123 3x10mL For the detection of antibodies (3%) K1393 Wr a -positive reagent red cells 3mL For the detection of antibodies (3%) K5010 Column Screen 123 3x10mL For the detection of antibodies (0.8%) Identification Donors are blood group O article number article name package description K1385 Makropanel 16 16x3mL For the identification of antibodies (3%) K1384 Makropanel 16P (papain) 16x3mL Papain treated cells, for the identification of antibodies (3%) K5020 Column Panel 16 16x3mL For the identification of antibodies (0.8%) Miscellaneous article number article name package K1150 Preservation medium for red cells 10mL

19 18 QUALITY CONTROL PRODUCTS Our quality controls help you to validate your reagents and manual or (semi)-automated procedures on a daily basis. Quality controls article number article name package description K1379 PeliControl panel 2x8mL For daily routine, internal quality control on the ABO/ Rhesus-D test, reverse blood typing and on antibody screening. Contains two whole blood samples. K1399 PeliControl CcEe-K 8mL For daily routine, internal quality control on Rhesus phenotyping and on K blood grouping. Contains one whole blood sample. Proficiency panels article number article name package description K1386 PeliCase 1 1 set Proficiency panel, routine blood group serology K1387 PeliCase 2 1 set Proficiency panel, advanced blood group serology

20 Blood group serology 19 SUPPORTING PRODUCTS Software for antibody identification Our Panel Interpretation Program can assist you with creating your exclusion panel and help you with antibody identification in an efficient and accurate way according to the Fisher Exact Method (p<0.05). article number article name description K3005 PeliPIP Software CD-ROM with software of the Panel Interpretation Program Immunohaematology books The book Immunohaematology is published by Sanquin and discusses the theoretical backgrounds of blood group serology/immunohaematolgy and has become indispensable in today s transfusion laboratory. article number article name description K3010 Erytrocytenserologie Dutch version K3010EN Immunohaematology English version

21 20 SPECIALISED PRODUCTS Platelet crossmatching and screening MTP based platelet test for the detection of anti-hla and anti-hpa platelet antibodies. article number article name package description K1360 MASPAT kit 96 tests One pre-coated microtiter plate and all required reagents K1139 MASPAT Indicator Red Cells 10mL 0.3% sensitised red blood cells for use in MASPAT kit K1367 MASPAT Screening Platelets 6mL Standardised platelets, ready for use in MASPAT kit to screen for anti-platelet antibodies K1368 MASPAT Screen kit 96 tests MASPAT kit and MASPAT Screening Platelets

22 Blood group serology Elution For easy and rapid acid elution of IgG antibodies from sensitised red blood cells. article number article name package description K1398 PeliStrip elution kit 15 tests Contains elution solution and neutralisation solution with a ph colour indicator. 21

23 22 PeliClass IgG subclass reagents Agglutination test to determine the IgG subclasses in case of an IgG positive DAT. article number article name package M1099 Anti-human IgG1 1mL M1101 Anti-human IgG2 1mL M1103 Anti-human IgG3 1mL M1105 Anti-human IgG4 1mL M1397 Control serum 1mL M1174 Set anti-human IgG and control serum 5x1mL

24 Blood group serology 23 INDEX Cellbind gel cards 2 Reagents for use in Cellbind gel cards ABO 3 Rhesus, Rhesus second line 4 Rare antigens 4 ABO (0,5% suspension) 5 Screening and identification (0,5 % suspension) 5 Cellbind LISS 5 Potentiating reagents BSA, PEG 14 LISS, Enzyme 15 Reagent red cells ABO, Coombs, Screening 17 Identification, Miscellaneous 17 Quality control products Quality controls, Proficiency panels 18 Cellbind equipment Manual 6 Semi-Automated, Fully Automated 7 Supporting products Software for antibody identification 19 Immunohaematology books 19 Reagents for blood group typing ABO 8 Lectines 9 Rhesus, Rhesus second line 10 Rare antigens, Controls 11 Anti-human globulin (Coombs sera) Monospecific 12 Polyspecific 13 Specialised products Platelet crossmatching and screening 20 Elution 21 PeliClass IgG subclass reagents 22 Index 23