Joint Programming in Neurodegenerative Disease Research (JPND)

Transcription

1 Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe Adriana Maggi JPND Vice-Chair Rome Dec 15, 2017

2 A European Research Area and beyond We cannot tackle neurodegenerative diseases by acting as single countries JPND is the largest global ND research initiative led by EU countries, with 30 participating EU member states Associated countries Third countries Increasing coordination of national research programmes to improve impact and effectiveness Australia Bulgaria Albania Austria Belgium Canada Croatia Czech Republic Denmark Finland France Germany Greece Hungary Ireland Israel Italy Luxembourg Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden Switzerland Turkey United Kingdom

3 Scope of the initiative Focus on Three Domains Scientific Animal models Biobanks Cohorts/registries Disease pathology Social Health care delivery Home automation Health economics Ethics Medical Early diagnosis Prevention Clinical trials

4 JPND brings together Researchers (Basic, Clinical, Healthcare/Social) National Funding Bodies National Research Strategies and Investments Industry

5 Referenti JPND - Italia Fabrizio Tagliavini Ministero Salute Aldo Covello MIUR Valeria Cardia MIUR Adriana Maggi Vice-chair

6 Implementing transnational and additional joint calls Total investment 128 M Joint Transnational Calls: o Between 20 and 175 proposals o Between 122 and 892 teams o 95 projects supported + ongoing 23 million call o including 24 projects in the Center of Excellence Network program

7 JPND JTC number of proposals Success rate from 30% to 12%

8 Come ha lavorato fino ad ora JPND Total investment 128 M Joint Transnational Calls: Portals: Current EU research projects on ND on human cohorts on animal models in Parkinson Between 20 and 175 proposals Between 122 and 892 teams 95 projects supported + ongoing 23 million call including 24 projects in the Center of Excellence Network program

9 2018 JPND call 2018 Multinational research projects on health and social care for Neurodegenerative Diseases Deadline March 2018

10 Attività future Call 2019 (risposta entro il 22/12) Personalized Diagnosis, prevention and care to promote researh aimed at changing the trajectory of ND through the development of personalized approaches: predictive diagnostic tools, preventive approaches and interventions, clinical and patient-oriented translational research Challenges of Brain Imaging in fundamental research and clinical studies harmonization and establishment of guidelines for future research and use of brain imaging in ND Discovery and validation of biomarkers for diagnosis and clinical studies discovery and validation of novel biomarkers for clinical usage: the call may :the call may equally target clinical and basic research and may even support existing cohorts as well as ethics of preclinical screening Genetic and environmental risk factors discovery and modelling of genetic and environmental risk factors which pronounces the pathogenetic relevance. Research dominated by fundamental research, might as well be open to cohorts support Model systems: from cells to animals cell and animal models are fundamental for clinical and translational researchand represent an excellent entering point for collaborative research projects of academics and industry: the call will focus on the translation from cell to animals and thus address fundamental research

11 Keep up to date Visit the JPND website: Sign up to the JPND News Feeds

12 Influenza sui contenuti futuro PQ Siamo stati consultati, tuttavia sono perplessa in quanto non ci sono state call sulle malattie neurodegenerative /brain nell ambito di Horizon 2020

13 Come ha lavorato fino ad ora JPND Total investment 128 M Joint Transnational Calls: Between 20 and 175 proposals Between 122 and 892 teams Portals: on human cohorts on animal models in Parkinson 95 projects supported + ongoing 23 million call including 24 projects in the Center of Excellence Network program

14 Aree di Focus JPND Disease areas Alzheimer's disease and other dementias Huntington's disease Motor Neurone Diseases Parkinson's disease and PD-related disorders Prion disease Spinal muscular atrophy (SMA) Spinocerebellar ataxia (SCA) Scientific Animal models Biobanks Cohorts/registries Disease pathology Social Health care delivery Home automation Health economics Ethics Focus on Three Domains Medical Early diagnosis Prevention Clinical trials

15 Attività future 2018 Multinational research projects on health and social care for Neurodegenerative Diseases Deadline March 2018

16 Attività future Call 2019 (risposta entro il 22/12) Personalized Diagnosis, prevention and care to promote researh aimed at changing the trajectory of ND through the development of personalized approaches: predictive diagnostic tools, preventive approaches and interventions, clinical and patient-oriented translational research Challenges of Brain Imaging in fundamental research and clinical studies harmonization and establishment of guidelines for future research and use of brain imaging in ND Discovery and validation of biomarkers for diagnosis and clinical studies discovery and validation of novel biomarkers for clinical usage: the call may :the call may equally target clinical and basic research and may even support existing cohorts as well as ethics of preclinical screening Genetic and environmental risk factors discovery and modelling of genetic and environmental risk factors which pronounces the pathogenetic relevance. Research dominated by fundamental research, might as well be open to cohorts support Model systems: from cells to animals cell and animal models are fundamental for clinical and translational researchand represent an excellent entering point for collaborative research projects of academics and industry: the call will focus on the translation from cell to animals and thus address fundamental research

17 Come i singoli gruppi possono partecipare Ricercatori di base e clinici tutti potranno essere finanziati Entrare in reti internazionali di ricerca

18 Referenti JPND - Italia Fabrizio Tagliavini Ministero Salute Aldo Covello MIUR Valeria Cardia MIUR Adriana Maggi Vice-chair