Research Area: Ecotoxicogenomics / Environmental Biotechnology/Plant Molecular Biology

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1 Dr. Meetu Gupta Assistant Professor (Sr.) Department of Biotechnology Jamia Millia Islamia, Central University New Delhi Research Area: Ecotoxicogenomics / Environmental Biotechnology/Plant Molecular Biology Research Interest: Heavy metal toxicity is one of the major environmental health problems in modern society, with potentially dangerous bioaccumulation through the food chain. When accumulated in excess in plant tissues, these metals can function as stressors causing physiological constraints and alterations in various vital growth processes, such as mineral nutrition, transpiration, photosynthesis, enzyme activities related to metabolism, and biosynthesis of chlorophyll and nucleic acids. My group is interested in studies on Plant-Metal Interactions from molecules to ecosystem. Work involves interaction of heavy metals with certain crop plants, metal-binding complexes, role of signaling molecules, toxicity reversal mechanisms, metal-ion interactions with micronutrients, impact of metal-ions on growth, photosynthesis and co-stress phenomena. The interactions of heavy metal with plants are analyzed at physiological, biochemical and molecular level with an aim leading towards phytoremediation or phytotechnology (green technology). Academic Qualification From May 2009 till date: Working as Assistant professor in the Department of Biotechnology, Jamia Millia Islamia, New Delhi September 2007 to May 2009: Worked as Assistant Professor in the Department of Biosciences, Jamia Millia Islamia, New Delhi Oct Sep 2007 (CSIR Pool Officer) Worked at School of Life Sciences, Jawaharlal Nehru University, New Delhi

2 Sep 2002-Sep 2005 (Principal Investigator, DST Young Scientist): Worked at School of Life Sciences, Jawaharlal Nehru University, New Delhi April 2002 to June 2002 Worked as Guest Researcher at Dept. of Pharmaceutical Biology, University of Wuerzburg, Germany. April 1997-March 2002 (CSIR Research Associate) Worked at National Botanical Research Institute, Lucknow Ph.D, (1996) - National Botanical Research Institute, Lucknow (Degree awarded from Banaras Hindu University, Varanasi) Bachelor of Science (B.Sc) and Master of Science (M.Sc.) from Banaras Hindu University, Varanasi with First Division. Projects Completed as PI: Three 1. From DST, New Delhi India for a period of three years from From University Grant Commission, India for a period of three years from From Ministry of Environment and Forest (MoEF), Govt. of India for a period of three and a half years from Awards and Achievements: National: Awarded DST-fast track Young Scientist-2002 Awarded SRA (Pool Officer) from CSIR, New Delhi, India, 2005 Awarded Research Associate (with higher slab) from CSIR, New Delhi, India, 1997 Awarded JRF and SRF from CSIR, New Delhi, India, 1992 & 1994 International: Awarded Guest Research Fellowship at University of Wuerzburg, Germany, 2002 Courses Taught at UG and PG level: Plant Diversity I (B.Sc. Biosciences) and (B.Sc. Biotechnology) Molecular Biology (B.Sc. Biosciences) Plant Diversity II (B.Sc. Biotechnology) Microbiology and Immunology (B.Sc. Biotechnology) Ecology/Environmental Biotechnology (B.Sc. Biotechnology) Ecology (B.Sc. Biotechnology, III semester) 2014-current Environmental Biotechnology (B.Sc. Biotechnology, V semester) current Environmental Biotechnology (M.Sc. Biotechnology, III semester) , current

3 Recombinant DNA Technology (M.Sc. Biotechnology, II semester) IPR issues (M.Sc. Biotechnology, III semester) , current Projects Guided at PG Level (last 6 years): S.No. Name Affiliation 1 Raghvendra Dubey (M.Sc Biosciences, JMI) 2 Sulekha Diwaker (M.Sc Biosciences, JMI) 3 Shilpa Bharti (M.Sc Biotechnology, JMI) 4 Asha Meena M.Sc Biotechnology, JMI) 5 Misfiqua M.Sc Biotechnology, JMI) 6 Afsana Parveen (M.Sc Biotechnology, JMI) 7 Farah Khanam (M.Sc Biotechnology, IFTM University, Moradabad) 8 Anjum Bi (M.Sc Biotechnology, IFTM University, Moradabad) 9 Medha Panthri M.Sc. Industrial Microbiology, DAV, Indore) 10 Divya Sharma B.Tech., Amity University) Ph.D Students: 1. Mohd. Anwar Ahmad (Awarded, currently working as Assistant Professor in Maulana Ali Jauhar University, Rampur) - Cellular/ molecular mechanisms involved for arsenic detoxification and tolerance in rice and Indian mustard varieties 2. Rashmi Gaur (Awarded, currently working as Post-Doc in School of Life Sciences, JNU, New Delhi)- Transcript analysis and molecular mapping of genes from chickpea (Cicer arietinum L.) 3. Shikha Gupta (Ongoing) 4. Chandana Pandey (Ongoing) 5. Ehsanullah Khan (Ongoing) 6. Afsana Parveen (Ongoing) Participation in different Departmental activities: M.Sc. Course Coordinator Time table In-charge Member of Syllabus, Equipment, Space, Moderation committee and Board of studies. Salient Achievements: Teaching Experience: > 7 years Research Experience: > 18 years Total number of papers published: 26 Total Citations: 801 (as on November 2014) H index: 14 i10 index: 18

4 List of Publications : Papers in Journals Impact Factor Chandana pandey and Meetu Gupta (2015) Selenium and auxin mitigates arsenic stress in rice (Oryza sativa L.) by combining the role of stress indicators, modulators and genotoxicity assay. J. Hazard. Mat. [accepted, IF: 4.3] 2. Meetu Gupta and Mohd. Anwar Ahmad (2014) Arsenate induced differential response in rice genotypes. Ecotoxicology and Environmental Safety. 107, [IF: 2.48] 3. Rashmi Gaur, Sabhyata Bhatia and Meetu Gupta (2014). Generation of expressed sequence tags under cadmium stress for gene discovery and development of molecular markers in chickpea. Protoplasma. DOI /s , [IF: 3.17] 4. Mohd. Anwar Ahmad and Meetu Gupta (2013) Exposure of Brassica juncea (L.) to arsenic species in hydroponic medium: comparative analysis in accumulation and biochemical and transcriptional alterations. Environ. Sci. Pollu. Res Y (IF: 2.75) 5. Mohd. Anwar Ahmad, Rashmi Gaur and Meetu Gupta (2012) Comparative biochemical and RAPD analysis in two varieties of rice (Oryza sativa) under arsenic stress by using various biomarkers. J. Hazard. Mat , , [IF: 4.3] 6. Rao K.P., Vani G., Kumar K., Wankhede D.P., Misra M., Gupta M. and Sinha A.K. (2011). Arsenic stress activates MAP kinase in rice roots and leaves. Arch. Biochem. Biophy. 506, [IF: 3.1] 7. Gupta M., Sharma P., Sarin N.B. & Sinha A.K. (2009) Differential response of arsenic stress in two varieties of Brassica juncea L. Chemosphere (74): [IF: 3.4] 8. Thoma, I, Loeffler, C, Sinha, A.K., Gupta, M., Krischke, M., Steffan, B., Roitsch, T. and Mueller, M.J. (2003) Cyclopentenone isoprostanes induced by reactive oxygen species trigger defense gene activation and phytoalexin accumulation in plants. The Plant Journal, 34, (Cover article). [IF: 6.98] 9. Gupta Meetu & Chandra P (1998) Mercury accumulation and physiological changes in rooted submerged plant Vallisneria spiralis L. Environ. Pollution, 103 (2-3) [IF: 3.90] 10. Gupta Meetu, Tripathi, R.D., Rai,U.N. & Chandra P. (1998) Role of glutathione and phytochelatin in Hydrilla verticillata (l.f.) Royle and Vallisneria spiralis L. under mercury stress. Chemosphere, 37(4): [IF: 3.4] 11. Rai, U.N., Gupta Meetu, Tripathi, R.D. & Chandra P. (1998) Cadmium regulated nitrate reductase activity in Hydrilla verticillata (l.f.) Royle. Water Air and Soil Pollution 106: [IF: 2.63]

5 12. Tripathi, R.D., Rai, U.N, Gupta Meetu & Chandra P. (1995) Cadmium transport in submerged macrophyte Ceratophyllum demersum L. in presence of various metabolic inhibitors and calcium channel blockers. Chemosphere. 31 (7) : [IF: 3.4] 13. Gupta Meetu, Rai U.N., Tripathi R.D. & Chandra P. (1995) Lead induced changes in glutathione and phytochelatin in Hydrilla verticillata (l.f.) Royle. Chemosphere 30 (10) : [IF: 3.2] Papers in Journals Impact Factor > Meetu Gupta and Chandana Pandey (2013) c-dna RAPD analysis in Oryza sativa and Brassica juncea under arsenic stress. Int. J. Adv. Res. 1(6), (IF: 1.67). 15. Gupta Meetu and Sarin N.B. (2009) Heavy metal induced DNA changes in aquatic macrophytes: RAPD analysis and identification of SCAR marker. J. Env. Sci. Vol. 21 (5), [IF: 1.70] 16. Ranade SA, Verma, A, Meetu Gupta, N. Kumar and (2002) RAPD profile- based distinction between Kapoori and Bangla types of Betel vine varieties. Biologia Plantarum 45(4) [IF: 1.74] 17. Gupta Meetu, Kumar A, Yunus, M. (2000) Effect of fly-ash on metal composition and physiological responses in Leucaena leucocephala (Lamk.) de. wit. Environ. Monitor. Assess., 61, [IF: 1.67] 18. Gupta Meetu (1999) Effect of lead and mercury on changes in protein profile in the aquatic macrophytes Hydrilla verticillata (l.f.) Royle and Vallisneria spiralis L. J. Environ. Sci. Health, 34(5), [IF: 1.64] 19. Tripathi, R.D. Rai, U.N., Gupta Meetu & Chandra, P. (1996) Induction of phytochelatin in Hydrilla verticillata (l.f.) Royle under cadmium stress. Bull. Environ. Contam. Toxicol. 56: [IF: 1.21] 20. Gupta Meetu & Chandra P. (1996) Bioaccumulation and physiological changes in Hydrilla verticillata (l.f.) Royle in response to mercury. Bull. Environ. Contam. Toxicol. 56 : [IF: 1.21] 21. Rai, U.N., Tripathi, R.D., Gupta Meetu & Chandra P. (1995) Induction of phytochelatin under cadmium stress in water lettuce (Pistia stratiotes) L. J. Environ. Sci. Health. A 30(9): [IF: 1.64] 22. Gupta Meetu & Chandra P. (1994) Lead accumulation and toxicity in Vallisneria spiralis and Hydrilla verticillata (l.f.) Royle. J.Environ. Sci. Health. A 29(3): [IF: 1.64] Papers in Journals Impact factor < 1 and with ISSN-ISBN Number 23. Meetu Gupta and Chandana Pandey (2013) Assessment of genotoxic effect of arsenic and selenium in Indian mustard (Brassica juncea L.) by using RAPD analysis. Pl. Arch. Vol. 13 No. 2,

6 24. Shikha Gupta and Meetu Gupta (2013) Indian mustard varieties (Brassica juncea) respond differently under selenium stress. Intern. J. Environ. Res. Develop. 3: Kumar M., Gupta Meetu., Srivastava D., Prasad M., Prasad U.S. and Sarin N.B. (2006) Genetic relatedness among Indian litchi accessions (Litchi chinensis Sonn.) by RAPD markers. Int. J. Agricul. Sci. 1 (4), [IF: 0.67] 26. Gupta Meetu, Tripathi R.D., Rai U.N. & Haq, W. (1999) Lead induced synthesis of metal binding peptides (phytochelatins) in submerged macrophyte Vallisneria spiralis L: Physiol. Mol. Biol. Plants, 5, [IF: 0.56] BOOK CHAPTERS: 1. Monika Jaggi, Meetu Gupta, Narendra Tuteja and Alok Krishna Sinha (2012) Mitogen activated Protein Kinases in Abiotic Stress Tolerance in Crop Plants: Omics Approaches. In "Improving Crop Productivity in Sustainable Agriculture" published by Wiley-Blackwell, Germany pp Dhamprakash P Wankhede, Meetu Gupta, and Alok Krishna Sinha (2013) Arsenic Toxicity in Crop Plants: Approaches for Stress Resistance. In "Crop Improvement Under Adverse Conditions" published by Springer, New York, pp Conferences / Workshops. Lecture / Seminars: S.No. Presented / attended Conferences, Workshops, Lectures, Seminars from (last 5 years) 1. Paper presented in 12th Annual Conference of Society of Science and Environment on Interdisciplinary Approaches in Environmental Sciences. at Department of Zoology, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, October 9-10, Paper presented in 4 th International conference on Plants and Environmental Pollution held by NBRI, Lucknow from 8-11 Dec, Attended 94 th Orientation Programme, organized by the Academic Staff College, Jamia Millia Islamia, New Delhi., 28 days (July 16, 2010 to August 16, 2010) 4. Paper presented in 80 th Annual Meeting of Society of Biological Chemists, held by CIMAP, Lucknow from th Nov Attended one day workshop, Biotikos on 15 th March 2011 in TERI, New Delhi 6. Attended 14 days workshop on Fermentation Technology held by Post Harvest Department, IARI, Pusa, New Delhi in December Participated in International Science Conference (I-ISC 2011) on Bioinformatics: An Interface between Computer Science and Biology, Organized by Centre for Interdisciplinary Research in Basic Sciences, Jamia

7 Millia Islamia, New Delhi 8. Paper presented in 81 st Annual Meeting of Society of Biological Chemists, November 9-11, 2012 at Science City Auditorium Complex, Kolkata, India. 9. Paper presented in International Conference on Sustainable Innovative Techniques In Civil and Environmental Engineering (SITCEE ) Organized by Krishi Sanskriti On 5th & 6th June 2013,Jawaharlal Nehru University, New Delhi. 10. Paper presented in International Conference On Various Facets of Energy Technologies and its Management for Sustainable Development (ET & MSD-2013) 16 th and17 th March at JNU, New Delhi. 11. Paper presented in 7 th Annual Convention of ABAP and International Conference on Plant Biotechnology, Molecular Medicine and Human health, October 18-20, 2013 at Department of Genetics, University of Delhi, South campus, New Delhi. 12. Attended 11th International Symposium on Rice Functional Genomics (ISRFG11) held during November 20-23, 2013 at hotel The Grand, New Delhi, India. 13. Attended Refresher Course as 2 nd Summer Special Programme from 16 th May th June 2014 (21 days) organized by the Academic Staff College, Jamia Millia Islamia, New Delhi 14. Delivered lecture as expert during ten day refresher training programme on Science, Social Science and Languages, organized by the Faculty of Education, Jamia Millia Islamia, New Delhi on 15 th may Paper presented in National Conference on Nanotechnology and Renewable Energy (NCNRE), April 28-29, 2014, Organized by Department of Applied Science and Humanities Faculty of Engineering and Technologies Jamia Millia Islamia, New Delhi. 16. Attended UGC-SAP Sponsored National Seminar on Metal Toxicity and Oxidative Stress from Sep, 2014, Organized by Department of Biosciences, Jamia Millia Islamia, New Delhi. 17. Paper presented in International conference on Emerging Trends in Biotechnology, November 6-9, 2014, organized by School of Environmental Sciences, JNU, New Delhi, India 18. Paper presented in National conference on Waste Disposal and its Effect on Biodiversity, November 15-16, 2014, organized by Mohammad Ali Jauhar University, Rampur.