Magnetic Resonance At the Heart of our Company

Transcription

1 Bruker News Eric Leonardis Regional Sales Manager Western&Southern Europe Bruker BioSpin, France BeNeLux Users Meeting Brussels, November 25 th, 2016

2 Magnetic Resonance At the Heart of our Company Committed to serve the MR community Continue to invest heavily in innovation with ~10% annual R&D investment Provide scientists with Cutting-edge innovations: e.g. GHz NMR technology, DNP-NMR Highest performance NMR, EPR, DNP, preclinical MRI instruments Drug discovery & development p plus QC tools for Biopharma High-value analytical solutions for Applied, Industrial & Clinical Markets: e.g. NMR FoodScreener, Avance IVDr, Minispec TD-NMR First-class global support and service, & after-market services: LabScape

3 Bruker Announces René Lenggenhager as BioSpin Group President Appointment of Dr. René Lenggenhager as President of the Bruker BioSpin Group, effective November 1st, 2015 Since 2004, Dr. Lenggenhager has served as General Manager for Laboratory Weighing at METTLER TOLEDO (MTD). Very successful track record in sustainable, profitable growth with a focus on customers and innovation Dr. René Lenggenhager combines academic and scientific qualification with international management skills.

4 The Richard R. Ernst Prize in Magnetic Resonance Inauguration of a new Prize to be awarded in an annual fashion at the European Magnetic Resonance (EUROMAR) conference Awarded to recognize recent beneficial applications of Magnetic Resonance going beyond fundamental research 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio Frydman, Robert Griffin, Wiktor Kozminski, Vladimir Sklenar, and Thomas Vosegaard

5 The Evolution of Magnetic Resonance Bigger and Better Innovation in Magnetic Resonance New Applications Productivity and Throughput

6 World's first shielded Aeon 1 GHz installed Active shielding reduces space requirements by > one order of magnitude Aeon 1 GHz magnets leverage advanced BEST superconductors Active refrigeration eliminates LN2, reduces LHe boil-off essentially to zero New GHz-class magnet, novel CryoProbes, 111 khz MAS probes, and new NMR methods expand frontiers in structural biology, membrane protein and intrinsically disordered protein (IDP) research Aeon 1 GHz at Research Center for Bio-Macromolecules at University of Bayreuth

7 Solid-State DNP Spectrometer Gyrotron and Klystron Options DNP with Gyrotron Work in Progress: 263 GHz Klystron Offer a lower-price more compact microwave source at 263 GHz Design compatible with possible upgrade later to gyrotron for full power performance Power output ~ 5W DNP with Klystron (EIK) Available 2017

8 Triple-Resonance 111kHz MAS 1GHz Probe Fully protonated 15N,13C Proteorhodopsin Courtesy: Guido Pintacuda, Daniela Lalli, ENS Lyon

9 Pharma: Shorter time-to-market Drug Discovery New TS tools facilitate FBS data analysis Complete workflow: samplepro Tube, samplejet, QCI/TCI, CMC_q & TS FBS tools! Process Understanding and Optimisation Growing InsightMR family with InsightXpress & InsightEPR InsightXpress greatly streamlines Rxn optimisation, monitors decay t 1/2 =1s! QC Potency by qnmr One single experiment determines the amount of active ingredient in a drug Rapid, selective, reliable method that frees the expert from routine testing! QC Quantification of Components in Solid Mixtures Rapid, push-button, bench top: The minispect mq20 + Dynamics Center Quantifies components based on their t1 saturation recovery curve

10 High Field Benchtop NMR: Lab2NMR Researcher sees this: The details:

11 Honey Profiling and updated Wine Modules of the NMR FoodScreener Authentication, fraud detection and labeling compliance enable brand protection, guarantee quality and protect investment and reputation of merchants Quickly gaining acceptance by global food analysis labs and honey-packers Stand-alone application modules further enhance ROI of our Food Screeners Fam. Michaud Apiculteurs, MELI first honeypackers to adopt novel NMR solution Wine module now includes extended coverage of regions in France, Italy and Spain Laboratory at Bruker for food authenticity and quality determination granted ISO/IEC accreditation

12 Preclinical Imaging Innovations New 3T Preclinical MRI System with Superior Cryogen-free Magnet and PET/MRI Option Novel, superior liquid cryogenfree 3 Tesla magnet No liquid Helium or Nitrogen filling required Magnet stays at field up to 4 hours during power or cold water failure Upgradable to PET/MRI

13 LabScape Service and Life Cycle for Support Magnetic Resonance & Preclinical Imaging New, flexible approach to lifecycle management, maintenance and service Maintenance, repair and upgrade agreements for NMR, EPR, MRI and other preclinical imaging product lines Reliable, optimal instrument performance Access to up-to-date expertise from trained engineers and applications scientists More at bruker.com/labscape

14 AVANCE Console Generations & Support AVANCE D*X: end of production 2000 AVANCE I: end of production 2004 AVANCE II: end of production 2006 AVANCE III: end of production 2012 AVANCE III HD: in production (since 2012)

15 AVANCE Console Generations & Support AVANCE II AVANCE II: 2016: 10 years end of production End of Service (EOS) January 2018, support on best effort at reasonable endeavour basis

16 A new look to a very successful site!

17 Announcement: Free TopSpin Processing Download your free version today!

18 Sales and Service organization in Benelux Bruker BioSpin Sales Sales Manager : Marc Penders Leiderdorp Sales engineer : Chu Sun Wong Application/Training Henny Janssen Service Brussels Michel Gilles (BE) Adri Schipper (NL) Henri van Etten (NL) Bert Van Zijl (NL) Back-office in Brussels and Leiderdorp

19 Welcome to our Guest Speaker! Dr. Alex De Groot Janssen Pharmaceutica Q2C-NMR: a new way of using NMR

20 Copyright Innovation 2011 Bruker Bruker with Corporation. Integrity Corporation. All rights reserved. All rights reserved.