RiboPrinter microbial characterization system

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1 DuPont Qualicon RiboPrinter microbial characterization system Staphylococcus epidermidis RiboGroup

2 OK. You found it. Now what? DuPont Qualicon

3 RiboPrinter microbial characterization system Only the DuPont Qualicon RiboPrinter system combines automation with the power to accurately identify and track sources of contamination at the strain level and gain control of your process and environment. Efficient and consistent identification of microorganisms. Unique genetic RiboPrint patterns are like DNA snapshots for an error-free match. The RiboPrinter microbial characterization system provides the speed, accuracy and resolution needed to identify microorganisms and characterize them efficiently and consistently. These determinations can be applied to virtually all bacteria. Using powerful genetic information, the RiboPrinter system provides an automated genetic snapshot, or RiboPrint pattern, of any bacterium in less than eight hours. RiboPrint patterns characterize environmental isolates, pathogens, spoilage organisms, control strains, beneficial organisms or any bacterium that is important to the pharmaceutical, personal care and food safety industries. Until now, the methods for genetic characterization of bacteria required highly skilled technicians and lacked standardization and consistency. The RiboPrinter system provides the speed, accuracy, reproducibility and confidence never before possible. From start to finish, the RiboPrinter system process is automated, simplifying operator training and minimizing errors due to technique. Loading and operating the characterization unit are easy and intuitive. The workstation software is user-friendly, providing sophisticated data analysis that eliminates the need for subjective interpretation of results. Only the RiboPrinter system combines automation and the power of DNA to go beyond identifying and documenting a problem. The RiboPrinter system produces an exact genetic snapshot of organisms, delivering the unparalleled power to track sources of contamination and gain control of any microbial environment. DuPont Qualicon

4 The flexibility to match any situation. With the RiboPrinter system restriction enzyme flexibility, ribotyping bacteria can be performed with either a prepackaged restriction enzyme or a custom configuration, while retaining the advantages of full automation. Greater speed and confidence throughout the day. Up to eight bacterial isolates can be tested at one time, with results available eight hours from sample input. Because the system can accept new batches every two hours, up to 32 samples can be loaded in a normal workday. This provides rapid, accurate results for great confidence in any product tested. Identification and Characterization The RiboPrinter system generates a RiboPrint pattern which is used to provide taxonomic identification (Genus species) of unknown isolates by an automated comparison to the onboard DuPont database of known patterns (or proprietary custom built databases). RiboPrint patterns can also be used to characterize strains of a common species. Control any microbial environment. The RiboPrinter system provides rapid, standardized identification and characterization of bacteria. The power to track and identify bacteria increases every time a sample is run. With a comprehensive, dynamic picture of any microbial environment, technicians can track and manage data at the strain level, letting them pinpoint contamination with more speed, ease and precision than ever before possible. Data Management Easy-to-use software features let you link detailed sample information to any pattern and allow you to manage sample data at the strain level. Tracking and Trending Identical sample patterns are automatically clustered into RiboGroups that allow you to instantly view previous occurrences of any particular pattern. DuPont Qualicon

5 Database The ever-expanding identification database includes more than 5,700 patterns, covering more than 180 genera and 1,200 species. Bacillus circulans Burkholderia cepacia Harnessing the power of DNA. More than the building blocks of life, DNA and technology that uses genetic information can be the foundation for powerful business results. DuPont Qualicon provides advanced, automated systems that use DNA to detect, identify and track the presence of environmental isolates, pathogens, spoilage organisms, control stains, beneficial organisms or other bacteria. Just as DNA information has forever changed the criminal justice system, the accuracy and speed of genetic-based solutions from DuPont Qualicon have revolutionized the detection and identification process for the pharmaceutical, personal care and food safety industries. Escherichia coli Micrococcus luteus Pseudomonas aeruginosa Staphylococcus aureus Staphylococcus epidermidis Leadership is in the genes. Leadership is not something that can be manufactured. For over 200 years, DuPont has been the leader in technological solutions with powerful business value. DuPont Qualicon is part of that strong tradition and has grown in technology, understanding and size to become a global leader in DNA-based diagnostic solutions. DuPont Qualicon supports current technology and customers, while developing new innovations and improving existing technology from a solid foundation of DuPont history. This ensures customers enjoy measurable business benefits today and well into the future. Stenotrophomonas maltophilia Streptomyces aureofaciens DuPont Qualicon

6 RiboPrinter system components Characterization unit (shown) Computer workstation (shown) RiboExplorer software/microsoft Windows based Laser printer Heat treatment station Handheld mixer Sample preparation rack DuPont Qualicon

7 DuPont Qualicon DNA-BASED COMMERCIAL DIAGNOSTICS SOLUTIONS qualicon.com DuPont Qualicon 3531 Silverside Road Bedford Building Wilmington, DE USA phone phone outside US fax DuPont (UK) Limited Wedgwood Way, Stevenage Herts SGI 4QN, UK +44(0) phone +44(0) fax DuPont Singapore Pte, Ltd. One Maritime Square, World Trade Centre Singapore phone fax inside cover: Escherichia coli The DuPont Oval logo, DuPont and The miracles of science are trademarks or registered trademarks of E.I. du Pont de Nemours and Company. RiboPrint and RiboPrinter are registered trademarks of Qualicon, Inc. Microsoft Windows is a registered trademark of Microsoft Corporation. 1A Copyright 2002 Qualicon, Inc. All rights reserved. Printed in the USA.