Back to Basics: Making Science Fun Again Bridging high school and University. Crystale Lim Siew Ying, PhD

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1 Back to Basics: Making Science Fun Again Bridging high school and University Crystale Lim Siew Ying, PhD

2 A little a out e BSc (Hons) Biomedical Science, UPM PhD (Molecular Medicine), UPM 2010 Lecturer, UCSI University 2013 Senior Lecturer, UCSI University 2016 Associate Professor, UCSI University crystalelim@ucsiuniversity.edu.my

3 My se o d ho e.

4 Undergraduate programmes

5 Postgraduate programmes

6 Strategies: Physical Attract attention, instill interest Show Tell - models and actual products - help to visualize abstract infomation

7 Strategies: Physical Attract attention, instill interest Group brainstorming - let them discuss, then compete!

8 Strategies: Solving cases Self-learning & critical thinking Case studies - learn a topic from a story - questions designed for understanding

9

10 Challenge: making science fun For students: boring classes

11 Challenge: making science fun For teacher: boring job

12 Challenge: no rote learning knowledge for exams, not everyday life

13 Challenge: no rote learning knowledge for exams, not everyday life

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17 School-UCSI activities

18 Outcome: lifelong learning Students today, leaders tomorrow

19 Going Gaga over Genetics: A Hands-on Introduction to Biotechnology Crystale Lim Siew Ying, PhD Faculty of Applied Sciences

20 DNA as genetic material DNA of all living things are unique

21 The Setup Preparation of materials by lab technicians

22 The Process Registration of participants (and teachers) Grouping of students into groups of 5 each Each student receives a handbook Gimmick: CSI agents walk-in Introduction of all facilitators LET THE FUN BEGIN!!!

23 The Case: Lady Gaga the Accused Use of facilitators dressed as FBI agents Powerpoint slides of the case background

24 Lady Gaga

25 Lady Gaga s Weird Dresses

26 Lady Gaga s Meat Dresses Where did the meat come from?

27 Where did the meat come from? DNA from the meat dress will be compared to the DNA of other eats

28 DNA fingerprints are unique!

29 What meat was used for the meat dress?

30 LET S INVESTIGATE WITH BIOTECHOLOGY!

31 Micropipette Crash Course

32 Training Module I: DNA extraction

33 DNA is the code that makes us who or what we are

34 DNA Extraction: The Process

35 DNA Extraction: The Process Gargling to get cheek cells Breaking the cell membrane Getting the DNA out Separating DNA from the unwanted stuff

36 DNA Extraction: The Process Spool DNA into colored alcohol Your DNA in a bottle forever!

37 Training Module II: Polymerase Chain Reaction

38 PCR: Making copies of DNA What happens in a PCR machine? Separation of DNA Binding of primers Copying of DNA using an enzyme Repeat 40 times!

39 PCR: The Process

40 Training Module III: Agarose gel electrophoresis

41 Agarose Gel Electrophoresis: Separate DNA by size

42 Agarose Gel Electrophoresis: An Introduction Loadi g practice: It s harder than it looks!

43 Agarose Gel Electrophoresis: An Introduction

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45 Training Module IV: DNA Fingerprint Analysis

46 DNA Fingerprinting: Identity matching Which 2 samples have matching DNA fingerprints?

47 DNA Fingerprinting: Solve the case! What meat is the meat dress from?

48

49 Winners get prizes! One workshop 1.5 hours POP QUIZ!

50 POP QUIZ!

51 Pop Quiz!!! What is the size of the circled DNA fragment?

52 Pop Quiz!!! A couple s son and daughter who went missing years ago. Now, they found 4 children, where they are sure 2 of them are the real son and daughter. They come to you to request a DNA fingerprinting test. Which of the children do you think are their son and daughter, and why?

53 Acknowledgement Postgraduate student facilitators + lab staff Faculty of Applied Sciences

54 Acknowledgement

55

56 We Our welcome past junior your scientists school! Workshops available: 1. Biotechnology 2. Microbiology 3. Food Science 4. Nutrition 5. Aquatic Science 6. More coming! Want a personalized science workshop? TALK TO US! crystalelim@ucsiuniversity.edu.my Want a workshop at YOUR SCHOOL? TALK TO US TOO!