Biomedical Engineering

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1 Biomedical Engineering A New Era of Multi-Disciplinary Research Jackrit Suthakorn, Ph.D. Norased Nasongkla, Ph.D. Panrasee Rittipravat, Ph.D. Pornpimol Sritongkham, Ph.D. Department of Biomedical Engineering, Faculty of Engineering, Mahidol University

2 Biomedical Engineering

3 Current Biomedical Engineering in Thailand Mahidol University: Multi-Research Track Department of Biomedical Engineering (1998) Ph.D., Master and Bachelor s Programs Chulalongkorn University: Bioelectronics and Tissue Engineering Research Ph.D. and Master Programs (2007) Chiang Mai University: Bio-image Processing Research Ph.D. and Master Programs (2006) KMITL: Medical Imaging Research Master and Bachelor s Programs (2012) Prince of Songkla University: Bio-Signal Processing Research Bachelor s Program (2007) Srinakharinwirot University: Generic Bachelor s Program (2008)

4 Department of Biomedical Engineering, Mahidol University Research Tracks: 1. Bio-signal and Image Processing 2. Tissue Engineering and Drug Delivery System 3. Advanced Computing in Medicine 4. Rehabilitation Engineering and Artificial Organs 5. Robotics and Computer-Integrated Surgery 6. Biosensors and Medical Instrumentation Number of Students: Ph.D. Program: Master Program: Undergrad Programs: 23 students 42 students 40 students/year

5 Department of Biomedical Engineering, Mahidol University Research Center and Labs: 1. Center for Biomedical and Robotics Technology (BART LAB) 2. Artificial Intelligent in Medicine Lab (AIM LAB) 3. Scaffold for Tissue Engineering Lab (STEN LAB) 4. Biopolymers and Nanoengineering for Drug Delivery and Molecular Imaging Lab (BioNEDD LAB) 5. Brain-Computer Interface Lab (BCI LAB) 6. Cardiovascular Engineering and Artificial Organs Lab (CardioArt LAB) 7. Biosensors and Bioelectronics Lab (BIOSENS LAB) 8. Neuro-EXploration Technology Lab (NEXT LAB) 9. Smart Motion and Rehabilitation Technology Lab (SMART LAB)

6 Collaboration Selected National Institutes: Mahidol University: 1. Faculty of Medicine Siriraj Hospital 2. Faculty of Medicine Ramathibodi Hospital 3. Faculty of Science 4. Faculty of Physical Therapy 5. Faculty of Medical Technology and Other Faculties Other Institutes and National Research Center: 1. NSTDA by NECTEC, MTEC and NANOTEC 2. Chulalongkorn University 3. Chulabhorn Research Institute 4. Thailand Center of Excellence for Life Sciences (TCELS) 5. National Cancer Institute 6. MOST, MOPH and MICT Selected International Institutes: 1. Johns Hopkins University, USA 2. Columbia University, USA 3. Harvard University, USA 4. University of Massachusetts, Amherst, USA 5. Case Western Reserve University, USA 6. University of California, Los Angeles, USA 7. Queen's University, Canada 8. Osaka University, Japan 9. Kyushu University, Japan 10. Seoul National University, Korea 12. National University of Singapore, Singapore 13. Nanyang Technological University, Singapore 14. University of Glasgow, UK 15. Medical University of Vienna, Austria 16. Bonn-Rhein-Sieg, Germany

7 Artificial Intelligence in Medicine Asst.Prof. Panrasee Ritthipravat

8 AI in Medical Applications Bioinformatics Medical Image Analysis CAD, CAS Robotics and Rehabilitation Prognosis Problems Biosignal Analysis Medical Reasoning Etc. Asst.Prof.Dr.Panrasee Ritthipravat

9 AIM LAB projects Computer Aided Diagnosis: IM-AIM IM-AIM supports NPC and bone tumor region identification from CT and MRI respectively. 3D visualization of the tumor can be viewed. Risk of NPC recurrence is provided for each patient. Asst.Prof.Dr.Panrasee Ritthipravat

10 AIM LAB projects Rehabilitation System for Stroke Patients Haptic and VR technologies are integrated into the system. Asst.Prof.Dr.Panrasee Ritthipravat

11 AIM LAB projects Therapeutic Robots for Children with ASD Asst.Prof.Dr.Panrasee Ritthipravat

12 What is a biosensor? Biosensors are diagnostic tools that can provide rapid results, are highly sensitive, simple to use, inexpensive, and can be miniaturized. Dr.Pornpimol Sritongkham

13 Multidisciplinary dimension of biosensor prototype design and system integration is shown in the diagram. Dr.Pornpimol Sritongkham

14 Biosensors and Bioelectronics Laboratory Current Researches An amperometric homocysteine biosensor for screening and point-of-care testing for patients with cardiovascular disease. Simultaneous determination of biomarkers for Alzheimer s disease using biosensor array and microfluidic chips. Electrochemical characterisation of coimmobilised enzymes/aunp/pedot-pss for acetylcholine detection. Paper-based microfluidic chip for using in electrochemical biosensor applications Dr.Pornpimol Sritongkham

15 Medical Robotics and Computer Integrated Surgery Main Applications: 1. Surgery 2. Rehabilitation and Diagnosis 3. Hospital Services and Logistics Jackrit Suthakorn, Ph.D.

16 Surgical Robotics and Navigation System Fluoro Navigation for Closed Intramedullary Nailing of Femur Banchong Mahaisavariya, Siriraj Hospital Supported by: National Metal and Materials Technology Center (MTEC) MU LapaRobot: ACooperative Surgical Robot for Laparoscopic Surgery Chumpon Wilasrusmee, Ramathibodi Hospital Supported by: National Research University (NRU) Breast Biopsy Navigation using Mammogram Image with RT Ultrasound Cholatip Wiratkapu, Ramathibodi Hospital Supported by: Mahidol University The Electronic Simulator Eye Model for Ophthalmic Anesthesia Adisai Varadisai, Chulalongkorn Hospital Supported by: National Science and Technology Development Agency (NSTDA) Jackrit Suthakorn, Ph.D.

17 Rehabilitation and Diagnosis Mems Based Intracranial Pressure Sensor for Traumatic Brain Injury Sorayouth Chumnanvej, Ramathibodi Hospital Supported by: National Research University (NRU) Colonoscope Tracking using Electromagnetic Tracking System Sathaporn Manatsathit, Siriraj Hospital Supported by: National Metal and Materials Technology Center (MTEC) BART LAB LL EXO 1: A Lower Exoskeleton for Spine Injured Patients Supported by: National Research Council of Thailand (NRCT) MAGIC Socks Chumpon Wilasrusmee, Ramathibodi Hospital Supported by: National Research University (NRU) Robotic Mono Filament Testing Device for Diabetic Neuropathy Chumpon Wilasrusmee, Ramathibodi Hospital Supported by: Mahidol University Jackrit Suthakorn, Ph.D.

18 Hospital Service and Logistics Robotics for Drug Dispensing and Delivery in Hospital Logistics Applications Golden Jubilee Medical Center Supported by: National Research Council of Thailand (NRCT) Jackrit Suthakorn, Ph.D.

19 Faculty Member: 3 Collaborators: 10 Full-Time Researcher: 4 Ph.D. Student: 7 Master Student: 13 Alumni: 20 Jackrit Suthakorn, Ph.D.

20 Brain Computer Interface Lab (BCI Lab) Department of Biomedical Engineering, Mahidol University Overview of BCI System

21 Selected Projects of BCI Lab Brain Controlled Wheelchair: Using brain wave to control the direction of wheelchair with the navigation and error correction system via laser scanner ithink2: Smart home control via brain wave Brain based Sleep Analysis: The 1 st sleep competition in the world to use brain wave as the alarm to wake people up from power napping International Patent System and Method for SSVEP Based Control of Electrical Devices PCT/TH2010/ Neurofeedback Device for Person with Mental Disabilities: The 1 st system to simultaneously use hemoencephalogram and electroencephalogram