Agilent s Portfolio for Food Safety. Ruby Ong Marketing Program Manager Chemical Analysis Group SAPK

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1 Agilent s Portfolio for Food Safety Ruby Ong Marketing Program Manager Chemical Analysis Group SAPK

2

3 A Heritage of Innovation: Varian & Agilent The acquisition will establish Agilent as a clear market leader in analytical solutions and give us the talent and technology base for creating unique new products and markets. - Bill Sullivan, President and CEO, Agilent Technologies

4 Today s Agilent Today s Agilent offers the broadest product portfolio in the industry and a robust and diverse pipeline to continually feed our customers quest for scientific innovation. Food Testing and Agriculture Energy and Fuels Environmental Forensics and Drug Testing Materials Science, Specialty Chemicals Pharmaceutical and Biopharmaceutical Clinical Diagnostics & Research Genomics, Metabolomics, Protein Studies Vacuum Solutions

5 Agilent Product Portfolio for Food Applications Product Categories include Gas Chromatography (GC) Liquid Chromatography (LC) Gel Permeation Chromatography (GPC) Mass Spectrometry (GCMS, GC-QQQ, etc.) Atomic Spectroscopy (AAS, ICP-OES, ICPMS) Molecular Spectroscopy (FTIR, UV-Vis) Dissolution Consumables and Supplies And many more

6 Food Applications Nutritional Labeling - Vitamins and Minerals Food Authenticity - Halal Verification - Organic Foods Food Safety - Contaminants and Residues - Pesticides / Herbicides Residues - Antioxidants and Mycotoxins - Preservatives and Additives - Allergens - Organic Residues (Dioxin, Melamine, PCB etc) - Illegal Dyes - Veterinary Residues - Heavy Metals Regulatory Bodies (Food) Malaysia Food Act 1983 & Food Regulation 1985 US Food Drug Administration (FDA) Agri-Food and Veterinary Authority of Singapore Japan Food Safety Commission

7 Agilent s Gas Chromatography Instrumentation Gas Chromatography Food Direct Injection of Fish Oil for the GC- ECD Analysis of PCBs Analysis of Preservative Additives in Food Analysis of Fusel Oils

8 Agilent s GCMS, GCMS/MS and Ion Trap Instrumentation GCMS and GCMS/MS Food Trace-Level Analysis of Melamine in Milk Products using GCMS Rapid Screening and Confirmation of Melamine and its Analogs in Baby Formula and Soy Products using GCMS/MS GCMS Approaches to the Analysis of Acrylamide in Foods

9 GC with Low Thermal Mass (LTM) Technology

10 Agilent s Liquid Chromatography Instrumentation HPLC Food Quantitative Liquid Chromatography Analysis of Melamine in Diary Products using Agilent's 1120 Compact LC and 1200 RRLC Determination of Acrylamide in Cooking Oil Ultrafast analysis of synthetic antioxidants in vegetable oils using the Agilent 1290 Infinity LC system

11 Agilent s LCMS (TOF, Ion Trap, Triple Quadrupole, Q-TOF) Instrumentation Food Rapid Screening and Confirmation of Melamine in Milk and Its Products by LCMS LCMS A Low Femtogram Target Screen Method for Perfluorinated Compounds in Food Matrices and Potable Water using Triple Quadrupole LCMS LC-TOFMS As a Tool to Support Can Coating/Food Interaction Studies

12 Agilent s Atomic Spectroscopy (ICPMS, ICP-OES, AAS) Instrumentation Atomic Spectroscopy (ICPMS, ICP-OES, AAS) Food Determination of Trace Metals in Food, Trace Metals in Edible Oil Determination of Isotope Ratios in Elements provided as Trace Element Supplements Measuring Metals in Proteins to monitor Elemental Absorption from the Diet

13 Agilent s Molecular Spectroscopy (FTIR) Instrumentation Food Molecular Spectroscopy (FTIR) Food Adulteration by FTIR Fats and Oils, Alcoholic Beverages by FTIR

14 Agilent s Nuclear Magnetic Resonance (NMR) Instrumentation Food Determination of Solid Fat Content or Ingredient Purity NMR Composition Studies of Food Ingredients / Fresh Vegetable Tissue Studies of the effects of Processing on Food Properties and Quality

15 Agilent Consumables and Supplies

16 Agilent s Analyzers

17 Agilent s Analyzers

18 Today s Quality Standards are Demanding and Increasing Importance on Food safety GxP or ISO/IEC requirements - proof of Instrumentation is suitable for intended use, proof of calibration and maintenance, proof of data quality Agilent Services and Support Predictable cost of ownership, all inclusive Service package Instrument Qualification service (IQOQ, FVS) Maintenance service Training (classroom and onsite) Consultancy

19 Agilent is uniquely positioned to forge the swiftest path toward new food safety applications Each year worldwide: Tens of millions of food-borne illness cases Hundreds of thousands hospitalized Thousands of lives lost Hundreds of billions (money) lost to food-borne illnesses Why? Globalization Aging populations Pathogens entering the food supply in new ways Opportunity: The demand for applications is growing significantly faster in the food testing industry than in any other segment

20 Agilent will be the first to harvest new food testing applications. Here s why. Uniting the chemical and biological components of food safety testing An established leader in chemical testing applications An emerging leader in biological testing space Deeply integrating customers into our application-development pipeline Knowledgeable sales force with close customer ties Agilent-sponsored lab-bench to lab-bench collaboration Local marketing resources such as people/research facilities localized throughout major geographic regions tied together through technology We were succeeding with customer collaborations decades before they became trendy

21 Agilent s Lab-bench to Lab-bench Market Development Model Create local research/technical development teams in Europe, the Americas, China, and India Identify key chemical and biological applications (unmet needs) Collaborate with respected researchers to make these applications a reality Support researchers world wide on specific applications Communicate our findings worldwide Commercialize successful applications

22 Agilent exclusive technologies dedicated to Food Safety Applications Biological Mass Code PCR reagents: highly multiplexed PCR techniques made possible by MS detection New Capability GC/Q-TOF technologies: extend Agilent s high-resolution accurate mass TOF technologies to GC Biological PCR/RFLP species identification: rapid, simple technique for food sample speciation In-depth Solutions Evolution and application of existing technologies to the analysis of pesticides, veterinary drugs, mycotoxins, dioxins, trace metals, allergens and other categories

23 Sample Preparation and Automation We make sample preparation cleaner, faster, and simpler with: High-performance auto-samplers and integrated systems that process more samples, faster SPE products that extract and concentrate samples from complex matrices A complete range of columns, supplies and reagents

24 By pinpointing emerging application needs Agilent will Become the #1 global leader in food safety, species identification and traceability technologies Achieve double-digit revenue growth from commercialized food applications by Maintaining existing applications Forging new applications with respected researchers worldwide As the food industry s premier measurement company, we will help our customers ensure the safety of the global food supply

25 What critical Chemical and Biological Food Safety application areas have our customers asked us to focus on?

26 Existing Core Chemical Applications GC/MS, LC/MS, GC/QQQ, LC/QQQ, LC/Q-TOF, LC/TOF, ICP/MS Pesticides Quantification of known pesticides Identification/quantification of new pesticides and metabolites Veterinary drugs Identification/quantification of antibiotics, steroids, and other growth hormones Trace metals Identification/quantification of elements such as lead and mercury The challenge: increase speed and sensitivity while decreasing cost

27 Emerging Chemical Applications Mycotoxins (over 300 known; immediate toxic effects) Typically LC/MS Steroid hormones (difficult to measure through conventional techniques) GC/QQQ Dramatic success in 2010 Winter Olympics Dioxins in food (traditionally requires high-res equipment/specialized skills) GC/QQQ Fast, simple, more sensitive than conventional GC approaches Marine toxins (small-molecule compounds produced by shellfish) LC/QQQ (quantification of known targets) LC/TOF (discovery of unknowns) Allergens (chemical aspects to identification) LC/MS, LC/Q-TOF, GC/QQQ Small-molecule allergens

28 Emerging Biological Applications Allergens (biological aspects to identification) LC/MS, LC/Q-TOF Intact protein discovery with bio-confirm software can determine the exact sequence of molecule in question Measurement by biological reagents Species identification (accidental contamination vs. intentional fraud) PCR, bioanalyzer, specialty bioreagents Identify biological compounds at the DNA level; Manipulate genetic information Pathogen identification (serotype) Mass Codes PCR with MS detection Identification at the DNA level DNA manipulation Tag and recognize dangerous bacteria Serotype determination At what point in manufacturing process is contamination taking place?

29 We ve talked about lab-bench to lab-bench collaboration Now, here s what Agilent brings to the bench

30 We bring: Supporting research efforts with: Hardware/software Supplies/consumables/reagents Expertise/training/services Communicating findings to respected leaders worldwide through: Peer-reviewed publications Technical seminars/workshops/webinars Individual consultations

31 To solve the toughest problems, we will partner with some of the world s best sites: Global food industry organizations Major laboratories Leading government agencies Prestigious universities Single-application sites Global leaders and emerging researchers in specific application areas Multi-application sites Sites with enough bandwidth to research multiple facets of the food industry at the same time Tackle multiple problems simultaneously

32 Only Agilent has the chemical and biological technology/measurement capabilities to support a comprehensive food safety program Only Agilent is prepared to put time, money, and talent toward finding and developing new food safety applications Only Agilent has created a collaborative process for meeting current and future food safety challenges