UCSD Department of Bioengineering

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1 UCSD Department of Bioengineering Adam J. Engler, Ph.D. Assistant Professor of Bioengineering, Biomedical Sciences Program and Material Sciences Program

2 University of California San Diego Founded in 1960s in La Jolla, California 7 th ranked Public University in the US US News and World Report 1 st in UC system for federal research funding (2008) Hottest University for Science Newsweek and 2006 Kaplan/Newsweek College Guide

3 Bioengineering at UCSD: Milestones 1966 Joint Program: AMES Department & School of Medicine 1975 NIH Bioengineering Training Grant 1991 Institute of Biomedical Engineering 1993 Whitaker Foundation Development Award ($5M) 1994 Department of Bioengineering 1998 Powell Foundation Gift for New Building ($8M) 1998 Whitaker Foundation Leadership Award ($18M) 1999 Whitaker Institute for Biomedical Engineering 2001 von Liebig Foundation: Center for Entrepreneurism ($10M) 2002 Powell-Focht Bioengineering Hall Dedication and Move-In 2008 Institute for Engineering in Medicine 2nd/4th ranked (Grad/Undergrad) Bioengineering Department US News and World Report $9.2M in extramural funding in FA09

4 Faculty, Scientists, and Students 24 Core Faculty 11 Affiliate Faculty 10 Adjunct Faculty 14 Research/Project Scientists 48 Postdoctoral Fellows 125 Ph.D. Students 28 M.S. Students 13 M. Eng. Students 837 Undergraduate Students in 4 Majors

5 Core Bioengineering Faculty 1966 Yuan-Cheng Fung 1966 Marcos Intaglietta 1976 David Gough 1979 Geert Schmid-Schönbein 1987 Andrew McCulloch 1988 Shu Chien 1992 Robert Sah 1994 Lanping Amy Sung 1995 Bernhard Palsson 1999 Shankar Subramaniam 2001 Michael Heller 2002 Jeff Hasty 2002 Xiaohua Huang 2003 Trey Ideker 2003 Gabriel Silva 2003 John Watson 2006 Melissa Micou 2007 Kun Zhang 2007 Karen Christman 2007 Shyni Varghese 2008 Adam Engler 2009 Gert Cauwenberghs 2010 Pedro Cabrales 2010 Ratnesh Lal

6 Our Mission Statement To improve health and quality of life by applying engineering principles to scientific discovery and technology innovation, and to train future leaders in Bioengineering through inspiring education and dedicated mentorship.

7 Our Vision: Integrative Bioengineering Bioengineering integrates: engineering with biological and medical science complex biomedical data into systematic models biological properties across physical scales research and education with technology transfer & healthcare Biology Medicine Academia Healthcare Education Engineering Industry Government

8 Powell-Focht Bioengineering Hall Space: 104,000 ft 2 2 Teaching Laboratories Multimedia Laboratory Y-C Fung Auditorium Graduate Student Lounge 17 Research Laboratories 2 Core Research Facilities Industrial Internship Office

9 Bioengineering Degree Programs BS Bioengineering (ABET) BS Bioengineering: Biotechnology (ABET) BS Bioengineering: Bioinformatics BS/MS: 5-Year Integrative Bachelor s/master s MS Bioengineering MEng Bioengineering MS/MD PhD Bioengineering PhD Bioinformatics (interdepartmental) MD/PhD (MSTP, PSP)

10 Bioengineering Degree (ABET) Bioengineering Core Science & Engineering Fundamentals 1: Introduction to Bioengineering BILD 1: The Cell 100: Introduction to Bioengineering Design CHEM 6A: Chemistry I 101: Foundations of Biomedical Imaging CHEM 6B: Chemistry II 103B: Bioengineering Mass Transfer CHEM 6BL: Inorganic Chemistry Lab 109: Bioengineering Statics & Dynamics PHYS 2A: Mechanics 110: Continuum Mechanics PHYS 2B: Electricity & Magnetism 112A: Biomechanics PHYS 2BL: Mechanics & Electrostatics Lab 112B: Biomechanics PHYS 2C: Fluids, Waves, Thermodynamics 122A: Biosystems & Control PHYS 2CL: Electricity & Magnet., Waves Lab 125: Modeling & Computation in MAE 3: Engineering Graphics and Design 130: Molecular Physical Chemistry MAE 9: C/C++ Programming 140A: Bioengineering Physiology MAE 140: Linear Circuits 140B: Bioengineering Physiology 172: Bioengineering Lab Math 186A: Principles of Biomaterials Design 20A: Calculus 186B: Principles of Bioinstrumentation 20B: Calculus 187A: Design Project: Planning 20C: Calculus & Analytic Geometry 187B: Design Project: Development 20D: Differential Equations 187C: Design Project: Implementation 20E: Vector Calculus 187D: Design Project: Presentation 20F: Linear Algebra XXXA: Design Elective Course "A XXXB: Design Elective Course "B Technical Elective (TE) Courses-2 Required MAE 107: Computational Methods in Engineering MAE 150: Computer-Aided Design Elective Courses MAE 170: Experimental Techniques 191, 197, 199 Humanities & Social Science

11 Biotechnology Degree (ABET) Bioengineering Core 1: Introduction to Bioengineering 100: Introduction to Bioengineering Design 103B: Bioengineering Mass Transfer 123: Systems Biology & Bioengineering 125: Modeling & Computation in 130: Molecular Physical Chemistry 160: Chemical & Molecular Tech. 161A: Bioreactor Engineering 161B: Biochemical Engineering 162: Biotechnology Laboratory 166A: Cell & Tissue Engineering 168: Biomolecular Engineering 186A: Principles of Biomaterials Design CENG 101A: Fluid Mechanics MAE 170: Experimental Techniques 187A: Design Project: Planning 187B: Design Project: Development 187C: Design Project: Implementation 187D: Design Project: Presentation XXXA: Design Elective Course "A XXXB: Design Elective Course "B Elective Courses 191, 197, 199 Humanities & Social Science Science & Engineering Fundamentals BILD 1: The Cell BIBC 100: Structural Biochemistry BIBC 102: Metabolic Biochemistry BICD 100: Genetics CHEM 6A: General Chemistry I CHEM 6B: General Chemistry II CHEM 6C: General Chemistry III CHEM 6BL: Inorganic Chemistry Lab CHEM 140A: Organic Chemistry I CHEM 140B: Organic Chemistry II MAE 9: C/C++ Programming PHYS 2A: Mechanics PHYS 2B: Electricity & Magnetism PHYS 2C: Fluids, Waves, Thermodynamics PHYS 2CL: Electricity, Magnet., Waves Lab Math 20A: Calculus 20B: Calculus 20C: Calculus & Analytic Geometry 20D: Differential Equations 20E: Vector Calculus 20F: Linear Algebra Technical Elective (TE) Courses-2 Required

12 Bioinformatics Degree Computer Science Science & Engineering Fundamentals CSE 11: Intro to Comp Sci-JAVA BILD 1: The Cell CSE 12: Basic Data Structures & Obj Oriented Design BILD 2: Multicellular Life CSE 21/Math. 15B: Math for Algorithms & Systems BILD 3: Organismic/Evolutionary Biol CSE 100/Math 176: Advanced Data Structures BILD 94: Prof Issues in Bioinformatics CSE 101/Math 188: Design/Analysis of Algorithms CHEM 6A: General Chemistry I CHEM 6B: General Chemistry II Math CHEM 6C: General Chemistry III 20A: Calculus CHEM 6BL: Inorganic Chemistry Lab 20B: Calculus CHEM 140A: Organic Chemistry I 20C: Calculus & Analytic Geometry CHEM 140B: Organic Chemistry II 20D: Differential Equations BIBC 102: Metabolic Biochemistry 20F: Linear Algebra BIBC 103: Biochemical Techniques 186: Probability Stats for Bioinformatics BIMM 100: Molecular Biology BIMM 101: Recombinant DNA Tech Bioinformatics BICD 100: Genetics 181: Molecular Sequence Analysis BICD 110: Cell Biology 182: Biological Databases PHYS 2A: Mechanics 183: Applied Genomic Technologies PHYS 2B: Electricity & Magnetism 184: Computational Molecular Biology Thermodynamics PHYS 2C: Fluids, Waves, BIMM 185: Bioinformatics Lab 130: Molecular Physical Chemistry Elective Courses 191, 197, 199 Humanities & Social Science Technical Elective (TE) Courses 3 Required

13 Major Flowcharts UCSD BIOENGINEERING: BIOINFORMATICS MAJOR (ALL COURSES REQUIRED FOR THE MAJOR MUST BE TAKEN FOR A LETTER GRADE.) Revised 01/15/09 UCSD BIOENGINEERING: BIOTECHNOLOGY MAJOR Accredited by the Engineering Accreditation Commission of the Accreditation Board for Engineering & Technology [EAC/ABET] FRESHMAN (ALL COURSES SOPHOMORE REQUIRED FOR THE MAJOR MUST BE JUNIOR TAKEN FOR LETTER GRADES.) SENIOR Fall Winter Spring Fall Winter Spring Fall Winter Spring Fall Winter Spring 20A (FW) FRESHMAN SOPHOMORE JUNIOR SENIOR 15B/ Fall 20B Winter 20C Spring 20D Fall Winter CSE21 Spring Fall 20F Winter Spring Fall Winter Spring (ALL COURSES REQUIRED FOR THE MAJOR MUST BE TAKEN FOR LETTER GRADES.) PHYS MAE 2CL 187A 187C 187D 9 or 10 FRESHMAN SOPHOMORE JUNIOR SENIOR (FWSSU) Fall Winter Spring Fall 2 UNITS Winter Spring Fall Winter 1 UNIT Spring Fall 1 UNIT Winter 1 UNIT Spring PHYS 2A PHYS PHYS2A PHYS 2BL 2B 2 UNITS UCSD BIOENGINEERING MAJOR PHYS 2C PHYS 2C B (F) 1 UNIT Revised 04/24/08 Accredited by the Engineering Accreditation Commission of the Accreditation Board for Engineering & Technology [EAC/ABET] MAE 9 or 10 (FWSSU) PHYS PHYS2B 2CL 2 UNITS MAE 3 (FS) 187B (F) 1 UNIT MAE 150 (FW) Revised 04/24/08 187D 1 UNIT 20A (FW) BILD PHYS94 2A (1 UNIT) 20B 20C PHYS BILD 2B 1 20D PHYS BILD 2C 2 20F BILD 3 (FS) 20E CSE100/ CENG 101A (F) CSE101/ B 187A 182 (F) 1 UNIT 166A (F) 187C 1 UNIT CSE 11 CHEM 6A 20A CSE (FW) 12 CHEM 6B 1* 1 UNIT 20B 1* 1 UNIT CHEM 6BL CHEM 6C CHEM 6BL 3 UNITS 20C BILD 1 20D CHEM 6BL 3 UNITS CHEM 140A 130 1* 1 UNIT 20F 109 1* 1 UNIT CHEM 140B BICD 20E100 BIBC102/ CHEM114B MAE 170 (FS) 101 (F) 110 BIMM100/ 123 (F) CHEM114C BICD 100 BICD A BIMM101/ CHEM112B 186B B 183 (F) 162 (F) 112B BIBC 161A 103 (F) DE # COURSE (F) 3 UNITS MAE (FS) DE ## COURSE 3 UNITS DE # COURSE 161B (F) UNITS TE TE BIMM DE ## COURSE 186A TE 3 UNITS BILD MAE CHEM CHEM CHEM 1 CHEM 140 CHEM BIBC BIBC 6A 6B 6C 140A (FW) 140A 140B B ** TE MAE 170 (FS) A TE 186A 125 CHEM CHEM 6A 6B TE Student Affairs/Undergrad Flowcharts/BINFFlowchart TE * 1 can be taken either in ** 191 is recommended but # DE COURSES (FALL): ## DE COURSES (WTR.): 119B, Electives: the Freshman or Sophomore Year. not required. For graduating seniors only. 119A, 126A,127A, 128A, 129A, 139A, 147A, 148A, 149A, 169A, or 126B, 127B, 128B, 129B, 139B, 147B, 148B, 149B, 169B, or 179B Student Affairs/UG Flowcharts/BTECFlowchart A. * 1 can be taken either in the Freshman or Sophomore Year. ** 191 is recommended but not required. For graduating seniors only. Student Affairs/UG Flowcharts/Flowchart # DE COURSES (FALL): 119A, 126A, 127A, 128A, 129A, 139A, 147A, 148A, 149A, 169A, or 179A. ## DE COURSES (WTR.): 119B, 126B, 127B, 128B, 129B, 139B, 147B, 148B, 149B, 169B, or 179B. Electives: ** 199

14 Follow Curriculum in General Catalog BIOENGINEERING: BIOINFORMATICS FALL WINTER SPRING FRESHMAN YEAR Math. 20A Math. 20B Math. 20C Chem. 6A Chem. 6B Chem. BL 1 / 6C CSE 11 CSE 12 BILD 94 (1 unit) 4 4 4

15 Advising Student Affairs program, scheduling, petitions advisory meetings Faculty career issues Biomedical Engineering Society panel discussions (streaming video) Career Services Office pre-med, Vet, Law, Business Colleges College vs. requirements

16 Undergraduate Studies Committee: Faculty David Gough (Co-Chair) Gabriel Silva (Co-Chair) Geert Schmid-Schönbein Melissa Micou Adam Engler Kun Zhang Gert Cauwenberghs

17 Bioengineering Student Affairs - Undergraduate Staff Betty Gunderson Director of Student Affairs Margene Wight Undergraduate S.A. Advisor Kelly Thorpe Undergraduate S.A. Advisor Kelly Escobedo Undergraduate Intake Advisor

18 BMES at a Glance Our goal is to provide students with guidance, services and events which will enhance both academic and professional development in the field of biomedical engineering and related topics. All while providing an environment to foster social interactions and good fun!

19 Instructional and Computing Facilities

20 Teaching Laboratories Biotechnology Laboratory: biochemical processes, cell culture, tissue engineering Bioengineering Laboratory: medical instrumentation, physiological measurement, biomechanics Bioengineering Design: Hands-on senior design projects

21 Integrative Bioengineering: Thematic Areas Multi-Scale Bioengineering: Integration from molecular to cellular, tissue, organ and systems levels. Measurement, analysis and manipulation from nano- to micro-, meso- and macroscales. Systems Biology: Integration of biological components into interaction networks and predictive models for understanding the dynamic emergent function of living systems. Regenerative Medicine: Engineering of (stem) cells and their microenvironment to repair, replace or regenerate injured and diseased tissues.

22 Regenerative Medicine Cardiac Regenerative Medicine Neural Engineering Cartilage Tissue engineering Muscle Repair Bioengineering Stem Cell Engineering Materials Engineering Blood substitutes

23 Multi-Scale Bioengineering Functional MRI Multi-scale Brain Imaging Molecular Biomechanics Cardiac Biomechanics Bionanotechnology Biosensors

24 Systems Biology Genome sequencing technologies Bioinformatics Biological network reconstruction Genetic Circuits Systems Biodynamics