EXTREME BIOTECHNOLOGY: High-performance Enzymes TM for industrial biocatalysis

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1 EXTREME BIOTECHNOLOGY: High-performance Enzymes TM for industrial biocatalysis Felipe Sarmiento, PhD Business Innovation Director North American Markets

2 Swissaustral has the know how to hunt down innovative enzymes for your specific industrial requirements

3 Our company exploits the potential of extreme microorganisms and their unexplored metabolic pathways as a unique and diverse source of industrial innovation. Swissaustral is a worldwide specialist on: EXTREME BIOTECHNOLOGY

4 SWISSAUSTRAL ACTIVITIES Swissaustral proprietary microbial Bio-bank of unique extremophilic microorganisms High-performance Enzymes TM Enzyme Discovery and Development Services TARGET MARKETS: Textile Pulp & Paper Detergents Feed Diagnostics Scientific research

5 OUR ENZYMES ARE DIFFERENT Isolated from Extremophiles PERFORMANT Optimal activity under extreme conditions RELIABLE Keep high activity in a wide range of temperatures and ph RESISTANT Can be scaled up and industrialized

6 INTERNATIONAL BIOTECH GROUP Monthey, Switzerland Athens, GA U.S.A. Santiago, Chile Through our High-Performance Enzymes and customized R+D Services we provide state of the art solutions that serve a wide range of industries worldwide.

7 v Developing High-performance Enzymes TM

8 SOURCE OF INNOVATION POWER OF EXTREMOPHILES 0 C Temperature 120 C 0 UV Resistance 100% 0 Salinity 4 M 1 ph 14 Psychrophiles optimal T < 15 C Thermophiles optimal T > 60 C Radioresistant UVA, B, C Halophiles [NaCl] > 3,5% Alkaliphiles ph > 9 Alcidophiles ph < 5

9 SWISSAUSTRAL BIOBANK Unparalleled Diversity Over 400 isolated strains Constantly Growing 15 new extremophiles per year High Quality and Novelty Unique microorganisms Biotechnological Potential Excellent source of extreme molecules

10 DEVELOPMENT PLATFORM FUNCTIONAL DISCOVERY EXTREME DEVELOPMENT OPTIMIZATION & SCALE-UP HIGH-PERFORMANCE ENZYMES TM Extremophilic Bio-prospection and Development (EBD) Platform Main engine of Swissaustral internal pipeline R+D Service Platform

11 Biocatalytic Solutions - One stop shop development service of customized enzymes - Diverse and proprietary microbial collection for extremophilic enzymes discovery - Specialized know-how for extremophilic enzymes development - Novel High-performance enzymes and wild type backbones for industrial applications

12 PRODUCT PORTFOLIO

13 High-performance Enzyme Microbial Recombinant Catalase - Discovered from a new psychrotolerant bacteria - Optimal activity at 40 ºC and ph=8 - Competitive price and scalable production - Long-term storage stability

14 Effective, Reliable & Resistant - It maintains over 75% of its activity in a broad range of temperatures - Textile, bioremediation and other applications

15 NEW PRODUCT! High-performance Enzyme Microbial Recombinant Glutamate Dehydrogenase - Diagnostic and other applications - It works over a broad range of temperature conditions (20-70 ºC)

16 SWISSAUSTRAL DEVELOPMENT PIPELINE OUR ENZYMES Laccase PROPERTIES Thermo-resistant and extreme alkaline enzyme Xylanase Thermo-resistant enzyme Lipases Thermo-resistant, stereospecific, highly active Nitrilase Thermo-resistant, stereo specific, highly active for aromatic and aliphatic substrates

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