DAVID HOEY University of Dublin (Trinity College) Dublin Postgraduate Diploma in Statistics

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1 300 W 107 th St #2C New York NY PHONE dh2460@columbia.edu DAVID HOEY PERSONAL INFORMATION Nationality: Irish Age: 27 ACADEMIC QUALIFICATIONS 2008 University of Dublin (Trinity College) Dublin Ph.D. by Research Awarded without correction. Thesis Topic Stress concentrations in bone cement: A critical distance approach Supervisor: Prof. David Taylor, Trinity Centre for Bioengineering, Trinity College Conducted extensive experimental testing on acrylic bone cement, investigating the role of stress concentrations in the fatigue strength of the material. Developed the theory of critical distances (TCD) to predict their role which can now be used in the future design of cemented artificial implants. The results from experimental testing have put forward many suggestions for improving the material as it used in vivo and put forward explanations for various inconsistencies regarding the material in the literature University of Dublin (Trinity College) Dublin Postgraduate Diploma in Statistics 2005 University of Dublin (Trinity College) Dublin Bachelor in Mechanical Engineering Awarded a First Class Honours (1.1) degree in Mechanical Engineering (BA/BAI) Final year subjects: Biomechanics, Management for Engineers, Mechanics of solids & materials, Thermodynamics & Heat transfer, Manufacturing technology & Systems, Mechatronics, Fluid dynamics Final year project: The strength and fracture of orthopedic bone cement. The success of this project led to my PhD described above. HONOURS AND AWARDS 2010 Society for Physical Regulation in Biology and Medicine, Tucson, Arizona Awarded Best Presentation in the Postdoctoral category for my paper entitled Determining the mechanisms of primary cilia bending in response to fluid shear stress IRCSET-Marie Curie International Mobility Fellowship in Science, Engineering and Technology Awarded prestigious INSPIRE fellowship, totaling 227,577 euro, which encourages Irelandbased researchers to avail of a structured period of overseas mobility with associated career development actions, followed by a corresponding return period in Ireland American Society of Mechanical Engineers Bioengineering Division Summer Conference, Marco Island, Florida. Awarded 1st place in the PhD Student Poster competition 2008 Invited to write article for Engineers Ireland Journal D. Hoey, D. Taylor, Study findings show potential for healthcare improvements.

2 Engineers Journal, 62(6), p , Reprinted in BEAI Spectrum: Biomedical and Clinical Engineering, Autumn Engineers Ireland biomedical research medal (2008) Awarded for making a significant contribution to the field of biomedical engineering research in Ireland 2007 Sir Bernard Crossland Symposium Awarded 1st place for demonstrating excellence in research in the mechanical engineering field with industrial relevance WORK EXPERIENCE May 2009 Present Columbia University in the City of New York New York, U.S. Postdoctoral Fellow May 2008 Present Primary Responsibility is to conduct experimental studies of cellular mechanosensing in bone as it relates to stem cell proliferation, homing, and differentiation, to publish this research in international academic journals and contribute to future research proposals on the area of bone mechanosensing. Lab management, entailing supervision of doctoral graduate and undergraduate students, ordering of lab equipment and supplies and general lab maintenance. International Academic Journal Referee Journal of the Mechanical Behaviour of Biomedical Materials Journal of Biomechanics Journal of Biomechanical Engineering Journal of the Mechanical Behaviour of Biomedical Materials Journal of Biomaterials Science: Polymer Edition Clinical Biomechanics 36 th Annual Northeast Bioengineering Conference, U.S September 2005 January 2009 University of Dublin, Trinity College Graduate Student Dublin, Ireland Ph.D. research and related research projects Forensic failure analysis Project Supervision Part-supervised two final year undergraduate research projects Co-supervised an undergraduate summer research project Head Teaching Assistant B3: Mechanics of Solids and Materials, Professor Luca Susmel 3B4: Materials, Professor David Taylor 2E8: Materials, Professor David Taylor Teaching Assistant E6: Engineering Science, Professor Henry Rice Laboratory Demonstrator B3: Strain Gauge Lab, Dr. Daniel Kelly September 2005 October 2008 David Taylor Forensic Failure Consultancy Forensic Research Engineer (Part-Time) Dublin, Ireland

3 Achieved extensive experience in failure analysis working on 16 projects, ranging from failure of cranes, hip implants, trampolines to plumbing fittings. Responsibilities included experimental testing, material analysis and preparing reports on my findings. Achieved strong interpersonal and communication skills dealing with individual clients and multinational corporations. June 2003 September 2003 Masonite International Corporation Mississauga, Canada Quality Engineer Achieved broad and diverse experience in numerous aspects of manufacturing. Responsibilities included quality control testing of all products and manufacturing systems. Worked daily with various groups of people, operating to strict deadlines. SKILLS PROFILE: Results Orientation Strong results orientation demonstrated by my results published in 6 academic journals, 11 academic conference proceedings and ain 1 book in the last four years (detailed below). Team Working and Leadership I have developed a strong level of team participation and leadership skills through working within teams research teams, project teams, line and operations teams throughout my academic and industrial career. I have also taken these skills and used them successfully through playing soccer for various clubs. Communications Excellent written and presentational skills. Making presentations to target audiences has been an integral part of my career thus far: e.g. presenting at international academic conferences to visiting schools to promote engineering. Applications Engineering: ANSYS finite element analysis, MatLab, Pro-Engineer Wildfire, AutoCAD, Minitab, MS-Word, MS-Excel, MS- Powerpoint, Paintshop Pro, ImageJ analysis software, Windows 95/98/NT/2000/Vista. Biology: Cell Culture Basics, Histology, Immunoctyochemistry, Immunohistochemistry, Cell loading via fluid flow, Western Blot, DNA/RNA/Protein Isolation, PCR, QRT-PCR, RNA/DNA transfection, RNA/DNA quanitification. Animal Work: Record keeping, Ear tagging, Breeding, Genotyping, Ulna loading, Sacrifice, Dissection, Tissue embedding and sectioning, Primary cell isolation, Histology. Journal Publications: D. Hoey, C.R. Jacobs, Primary cilia is a mechanosensor in bone, Journal of the American Academy of Orthopedic Surgery, In Press (Review Paper)

4 D. Hoey, D. Taylor, The effect of mixing technique on fatigue of bone cement when stress concentrations are present, International Journal of Nano and Biomaterials, In Press D. Hoey, D. Taylor, Statistical distribution of the fatigue strength of porous bone cement, Biomaterials, 30(31), p , D. Hoey, D. Taylor, Quantitative analysis of the effect of porosity on the fatigue strength of bone cement, Acta Biomaterialia, 5(2), p , D. Hoey, D. Taylor, Comparison of the fatigue behaviour of two different forms of PMMA, Fatigue and Fracture of Engineering Materials and Structures, 32(3), p , D. Taylor, D. Hoey, High cycle fatigue of welded joints: the TCD experience, International Journal of fatigue, 31(1), p 20-27, D. Hoey, D. Taylor, Fatigue in porous PMMA: the effect of stress concentrations, International Journal of Fatigue, 30(6), p , 2008 Book Publications: R.Y. Kwon, D.A. Hoey, C.R. Jacobs, Mechanobiology of Primary Cilia, Cellular and Biomolecular Mechanics and Mechanobiology, Ch 18, Springer, In Press Conference Publications: M. Downs., F.A. Herzog, D. Hoey, C. R. Jacobs, Analysis of Primary Cilia Deflection Under Laminar Fluid Flow with 3D Imaging and Advanced Modeling. In: Proceedings of the Biomedical Engineering Society Conference, Austin, Texas F.A. Herzog, J. Geraedts, D. Hoey, C. R. Jacobs, A Mathematical Approach to Study the Bending Behavior of the Primary Cilium. In: Proceedings of the North East Bioengineering Conference, New York, New York D. Hoey, J. Geraedts, C. R. Jacobs, Determining the mechanisms of primary cilia bending in response to fluid shear stress. In: Proceedings of the Society for Physical Regulation in Biology and Medicine Conference, Arizona, D. Hoey, D. Carette, P. O Reilly, D. Taylor, The role of stress concentrations in the bone cement mantle. In: Proceedings of the ASME Bioengineering Division 2008 Summer Bioengineering Conference, Florida D. Hoey, P. O Reilly, D. Taylor, Fatigue in PMMA: the effect of notches and pores predicted using the TCD. In: Proceedings of European Conference of Fracture, Brno D. Hoey, D. Taylor, The role of porosity in the fatigue strength of bone cement: the importance of pore size and pore distribution. In: Proceedings of the Second International Conference on the Mechanics of Biomaterials and Tissues. Hawaii, D. Hoey, The role of stress concentrations in the fatigue strength of porous PMMA. In: Proceedings of 10th annual Sir Bernard Crossland Symposium, Galway D. Hoey, D. Taylor, Using the Theory of Critical Distances with FEA to predict Fatigue Failure in Bone Cement. In: Proceedings of the European Society of Biomechanics Workshop, Dublin D. Hoey, P. O Reilly, D. Taylor, Fatigue behaviour of PMMA vs PMMA based bone cement. In: Proceedings of the 14th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Sligo D. Hoey, P. O Reilly, D. Taylor, The role of defects in the fatigue strength of bone cement. In: Proceedings of the 13th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Fermanagh 2007.

5 D. Hoey, P. O Reilly, D. Taylor, Predicting fatigue failure in bone cement. In: Proceedings of the 12th Annual Conference of the section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway D. Taylor, D. Hoey, L. Sanz, P. O Reilly, Fracture and fatigue of bone and bone cement: The critical distance approach. In: Proceedings of European Conference of Fracture, Alexandroupolis Papers in Preparation: D. Hoey, D. Carette, P. O Reilly, D. Taylor, The role of stress concentrations in the bone cement mantle of an artificial hip implant. Planning to submit to Journal of Orthopaedic Research. D.A. Hoey, C.R. Jacobs, The Mechanics of the Primary Cilium: An Intricate Structure with Complex Function. Planning to submit to the Journal of Biomechanics (Review Paper) Interests and Activities: Full member of Engineers Ireland (M.I.E.I) Full member of the Society of Physical Regulation of Biology in Medicine (SPRBM) Associate member of the Orthopedic Research Society (ORS). Volunteering (Visit schools to promote engineering) Sports and fitness including soccer, running, golf, basketball, rugby and gaelic. I have represented teams in all sports and currently play for EMCFC first team, NY. Music (Piano) and travelling. Photography Referees: Upon request Curriculum Vitae Closed 22 nd September 2010