Cracking the Code of Life -Video Questions

Transcription

1 Cracking the Code of Life -Video Questions 1.What is the human genome? 2.What did the video say about the genes found in a banana? 3.What is the value of mapping the human genome? 4.How similar are all of the babies born into the world each day? 5.How many base pairs make up the human genome? 6.How long did it take scientists to locate the gene that causes Huntington s disease? 7.How many incorrect base pairs does it take to cause a person to have a specific disorder? 8.What genetic disorder affects baby Hayden? 9.Tay-Sachs disease results from the lack of a specific protein in the body. What is the role of that protein? 10.How does the lack of this protein affect the brain? 11.Is there a cure for Tay-Sachs disease? 12.Charlie and Blithe, and Tim and Allison are all for the Tay-Sachs gene. 13.What are some of Hayden s symptoms?

2 14.What does the narrator of the video say the major role of the human genome system should be? It should act as 15.What year did Congress give consent to the National Human Genome Project? 16.What private entrepreneur started his own genome team, in an effort to create competition and speed up the genome sequencing process? 17.The video discuss new high-tech machine used to study DNA. What equipment was used to bounce light of the dyed DNA samples? 18.What color did cytosine appear on the computer screen? 19.Where did Craig Venter grow such a profound respect for human life? 20.What is the name of Dr. Venter s private corporation? 21.What machine was the MIT research group so excited about? 22.How much did the machine cost? 23.Which human beings are being mapped in the public project? 24.Which human beings are being mapped in the private project? 25.Why do we have so many genes in common with a banana? 26.What milestone did the public project achieve in 1990? 27.What proportion of the genome is this?

3 28.How long does it take to process a patent? 29.How many genetic patents are "pending" at any given time? 30.How much money did it take for Craig Ventner to start his company Celera? 31.What is wrong with Riley Dimonche? 32.What are the symptoms of his disease? 33.How many "letters" are missing in his DNA? 34.What causes the disease Riley has? 35. information is linear; are 3-D 36. is a collection of all your genes and DNA 37. is a collection of all of your proteins 38. How many genes are there? 1. genes in a human being 2. genes in a mouse 3. genes in a fruit fly 39.How many proteins do you have? 40.How long will it take to know what all the proteins do? 41.How to find a gene for a disorder: 1.take of a person who is affected 2. compare it to 3. The comparison is best if people are

4 42.What makes Iceland a perfect place to look for genes that cause disease? 43.How much money did the company Decode pay for exclusive access to Iceland's medical records? 44.How did the doctors feel about this? 45.How many nucleotides are different with the BRCA mutation? 46.What percentage of women with BRCA mutations will develop breast cancer? 47.What percentage of breast cancers are caused by BRCA? 48.After the "parts list" of the genome is assembled, what is the next job? 49.What happened in June 2000? 50.What proportion of the genome is actaully made up of genes? 51.What is Eric Lander's response to the similarity among all the genomes?

5 Deeper Thinking - Please answer the following questions in complete sentences. 1. Think back to baby Hayden. Was Hayden s disease a result of faulty sex chromosomes or faulty non-sex (autosomal chromosomes)? Explain. 2. Why is it not surprising that Hayden s dad Tim and his brother Charlie are both carriers for Tay-Sachs? 3. Why would the government put so much money into the human genome project if a private company is already doing it? 4. Why can a map of the genetic code of only a few people help all mankind? What about the genome makes this information transferable? 5. If the probability Lissa's daughter inherited her gene for breast cancer is 50%, is BRCA dominant or recessive? Explain your answer 6. If we share so many genes with a banana, what makes humans different? What do you think it is?