COURSE INFORMATON BTEC 504. Prof. Dr.Recep Serdar Alpan. Prof. Dr.Recep Serdar Alpan Prof. Dr. Ece Genç NONE

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1 COURSE INFORMATON Course Title Code Semester PHARMACEUTICAL AND MEDICAL BIOTECHNOLOGY BTEC 504 T+U Hour Credits ECTS Prerequisites Language of Instruction Course Level Course Type Course Coordinator Instructors Assistants Internship Goals Content English MSc and PhD Degrees Elective Prof. Dr.Recep Serdar Alpan Prof. Dr.Recep Serdar Alpan Prof. Dr. Ece Genç To understand theoretical background of the application of biotechnology techniques and applications on therapeutic products, gene therapy, gene application techniques, tissue engineering, antibody engineering, monoclonal antibodies, vaccines, sera and pharmaceutical applications. Introduction to Medical Biotechnology; Protein isolation and expression technics in Medical Biotechnology; Biotechnology in Pharmaceutical Production; Tissue Engineering; Monoclonal antibodies and cellular targeted immunologic therapeutic applications; Drug development with Recombinant DNA Technology; Gene Therapy Applications in Medicine sirna, Micro-RNA Drugs; Recombinant Vaccines; Drugs that reverse Drug Resistance Course Learning Outcomes Program Learning Teaching Methods Assessment Methods

2 1) Understands theoretical background of the application of biotechnology techniques and applications on therapeutic products Outcomes 2,4,9 1,2 A,C,D 2) Learns types of cells used in Tissue Engineering and Recombinant technology 2,3,4,7 1,2 A,C,D 3) Learns Gene Therapy and effect on ethics 2,3,4,7 1,2 A,C,D Teaching Methods: 1: Lecture, 2: Question-Answer, 3: Laboratory, 4: Case-study Assessment Methods: A: Testing, B: Laboratory, C: Homework, D: Project COURSE CONTENT Week Topics Study Materials Introduction to Medical Biotechnology Protein isolation and expression technics in Medical Biotechnology Biotechnology in Pharmaceutical Production Tissue Engineering Monoclonal antibodies and cellular targeted immunologic therapeutic applications Drug development with Recombinant DNA Technology I Drug development with Recombinant DNA Technology II Mid-term Gene Therapy Applications in Medicine I Gene Therapy Applications in Medicine I sirna, Micro-RNA Drugs

3 Recombinant Vaccines I Recombinant Vaccines II Drugs that reverse Drug Resistance RECOMMENDED SOURCES Textbook Additional Resources Pongracz & Keen, Medical Biotechnology, Churchill Livingston, Elsevier Current s about Medical Biotechnolgy MATERIAL SHARING Documents Assignments Exams Lecture notes are given to students Project assignment sheet containing project subjects and directions about how to prepare presentation is given to students 1 Midterm, 1 Project Presentation and 1 Final ASSESSMENT IN-TERM STUDIES NUMBER PERCENTAGE Mid-terms 1 50 Term Project 1 50 CONTRIBUTION OF FINAL EAMINATION TO OVERALL GRADE CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE Total Total 100 COURSE CATEGORY Field Courses

4 COURSE'S CONTRIBUTION TO PROGRAM No Program Learning Outcomes Contribution Level Advanced level knowledge of mathematics, statistics, and bioengineering. The ability of designing biological systems, analysis or process in order to meet up with the desired requirements/products. 3 4 The ability of identification and describing the engineering problems in biotechnology and bioengineering and proposing solution by making use of most up-to-date techniques and instruments. The ability of working efficiently in interdisciplinary teams and being definitive in decision making process by taking responsibilities. 5 The ability of developing efficient communicating skills in the field of biotechnology and presenting oneself efficiently in social and scientific arena/platforms. 6 The ability to have occupational ethics and social responsibilities, intellectual conscious in areas of professional conversations, declarations, and applications The ability of perceiving occupational ethics and their implications on the society at legal and economic level. The ability of retaining the necessity of lifelong education, learning, and improvement and gain the skills to achieve this. The ability of perceiving the impact of bioengineering, genetics, and biotechnology products and solutions at the environmental, global and social levels. The ability to express oneself in English orally and in writing at global platform. Activities ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION Course Duration (Excluding the exam weeks: 14x Total course hours) Quantity Duration (Hour) Total Workload (Hour) Hours for off-the-classroom study (Pre-study, practice) Mid-term examination 1 3 3

5 Laboratory Homework Project Final examination Total Work Load 186 Total Work Load / 25 (h) 7.44 ECTS Credit of the Course 8