INTERNATIONAL PROTEOMICS & METABOLOMICS CONFERENCE AND ADVANCED PROTEOMIC SCHOOL NOVARA, JUNE 2018

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1 INTERNATIONAL PROTEOMICS & METABOLOMICS CONFERENCE AND ADVANCED PROTEOMIC SCHOOL NOVARA, JUNE 2018 Conference: High-throughput MS-based proteomics and metabolomics: from cells to clinic Novara, June 25th, 2018 Campus Perrone, University of Piemonte Orientale, Via Perrone 18, 28100, Novara Short Proteomic School: Mass spectrometry-based proteomics for cells: from sample prep to big-data analysis and interpretation Novara, June 26th, 2018 Campus Perrone, University of Piemonte Orientale, Via Perrone 18, 28100, Novara

2 We have the pleasure to invite all of you to the High-throughput MS-based proteomics and metabolomics: from cells to clinic conference that will be held in Novara on the 25 th of June. The aim of this conference is to: provide a scientific forum to present and promote the use of MS-based proteomics and metabolomics in the biomedical field; report the recent advances in the proteomics and metabolomics analyses from cells to translational medicine and clinic; transfer to the participants the know-how on the currently available methods for proteins and metabolites analysis from cells and their different compartments. Oral abstracts will be selected for oral presentations. Outstanding poster abstracts submitted by May 5, 2018, will be selected for two short oral presentations. All abstracts, including those selected for the conference, will be scheduled for poster presentation in Poster Sessions held on the exhibitor floor. Posters shall be put up by 9:30 AM and available for viewing throughout the day until 17:00 PM. Authors will be present during Poster Sessions held daily from 10:40 11:00 and 15:40 16:15 on the Exhibit Floor. During the conference the scientific committee will award two poster prizes of 300,00 for researchers under 35 years of age. The Division of Mass Spectrometry of the Italian Chemical Society (DSM-SCI) awards 5 fellowships, up to 100,00 for Italian participants and 200,00 for foreign participants, for the participation of young researchers. The conference will be followed on the 26 th of June by a Short Proteomic School: "Mass spectrometry-based proteomics for cells: from sample prep to big-data analysis and interpretation". The school aimed to give advanced education in mass spectrometry to graduate, PhD, post-doc students, and young scientists working in the areas of proteomics. The school should also be useful for allowing meeting of scientists and for creating new links among mass spectrometrists but also end users. More information at the website:

3 Scientific Program 8:30 9:15 Registration 9:15 9:30 Opening Ceremony 9:30 10:10 A multi-omics population approach for understanding the aging mouse liver Evan G. Williams - Institute of Molecular Systems Biology of ETH Zurich, Switzerland 10:10 10:40 "Metabolomic approach to validate a novel mitochondrial regulator" Nico Mitro & Donatella Caruso - Università degli Studi di Milano, Italia 10:40 11:00 Coffee Break & Poster session 11:00 11:40 Metabolomics applications in biomedical research" Tomáš Čajka - Institute of Physiology CAS, Dept. of Metabolomics, Czech Republic and UC Davis Genome Center, NIH West Coast Metabolomics Center, California, USA 11:40 12:00 Selected oral presentation 12:00 12:20 Metabolomics applications with LC-MS, oral by SCIEX 12:20 12:40 GC-MS applications in biomedical field oral by LECO

4 :00 Lunch Break 14:00 14:40 Challenges in biomarker validation for bladder cancer monitoring Jerome Zoidakis - Biomedical Research Foundation, Academy of Athens, Greece 14:40 15:10 "MALDI-MS Imaging of glomerular diseases: from the research to the clinical laboratory?" Andrew Smith & Fulvio Magni - Università degli Studi di Milano Bicocca, Italia 15:10 15:40 "A target fishing and proteomic approach to study in vitro the effect of a new drug on M. tuberculosis" Marcello Manfredi & Emilio Marengo - Università del Piemonte Orientale, Italia 15:40 16:15 Coffee Break & Poster session 16:15 16:35 MALDI-MS Imaging for tissue analysis, oral by SHIMADZU 16:35 16:55 Two selected short oral presentation 16:55 17:05 Best poster award 17:05 17:15 Closing remarks

5 Short Proteomic School Mass spectrometry-based proteomics for cells: from sample prep to bigdata analysis and interpretation Preliminary program: 9:30-9:45 Welcome e introduction 9:45-10:30 Sample preparation, pre-fractionation methods and organelle isolation (Cecconi Daniela, Brandi Jessica) 10:30-11:15 MS-based proteins identification (Manfredi Marcello) 11:15-12:15 MS-based proteins quantification (Manfredi Marcello) 12:15-13:00 Chemometrics and Statistics and data analysis (Marengo Emilio, Robotti Elisa) 13:00-14:00 Lunch 14:00-14:30 Analytical challenge and case studies in proteomics (Cecconi Daniela, Brandi Jessica) 14:30-15:15 Hands-on: MS spectra interpretation, database searching and processing 15:15-16:00 Hands-on: data analysis, gene ontology classification, pathway enrichment, proteins interaction and interpretation 16:10-17:00 Hands-on: case study, pharmacoproteomics of antitumor molecules against Cancer Cells

6 Call for Abstracts: 27 February 2018 Abstract submission deadline: 5 May 2018 Notification to authors: 15 May 2018 Registration deadline: 20 May 2018 Quote: WORKSHOP (coffee breaks and lunch included): Students, PhD Students, under 35: free AICC and DSM Members: 50,00 Non-Members: 70,00 On site 85,00 SCHOOL (coffee breaks and lunch included): AICC, DSM Members, PhD students: 100,00 Others: 150,00 Workshop + school (AICC, DSM members): 120,00 Workshop + school (Others): 180,00

7 Awards and Fellowships POSTER AWARDS During the conference the scientific committee will award two poster prizes of 300,00 for researchers under 35 years of age. You need to provide the poster in portrait format with maximum dimensions of 110 x 140 cm (width x height). FELLOWSHIPS FOR PARTICIPATION OF YOUNG RESEARCHERS The Division of Mass Spectrometry of the Italian Chemical Society (DSM-SCI) awards 5 fellowships for the participation of young researchers to the International Proteomics & Metabolomics Conference that will be held in Novara (Italy) on June 25th, The fellowships are reserved to young researchers under 35 years at June 25th, 2018 with no permanent position jobs who are engaged in scientific or educational activities at Universities, research and control Centers (i.e. PhD, post-doc students and scholarship holders). The fellowships consist in the travel reimbursement, upon deposit of original receipts for travel expenses incurred, up to 100,00 for Italian participants and 200,00 for foreign participants. Fellowship requests must be sent by May 15th, 2018 to Prof. Donatella Caruso Dept. Pharmacological and Biomolecular Sciences, Via Balzaretti 9, Milano, phone donatella.caruso@unimi.it The applications must be accompanied by: a) A short curriculum vitae; b) Applicant s status declared by his/her supervisor; c) Title and abstract of the communication. Recipients will be informed by May 30, The provision of the fellowship must be acknowledged in the oral presentation if it will be selected, or in the poster by using the logo of DSM-SCI. This logo must only be used for this presentation and must be deleted from the recipient s computer following the presentation.

8 Committees Organizing committee: Daniela Cecconi (University of Verona) Marco De Andrea (University of Turin/University of Piemonte Orientale) Massimo Donadelli (University of Verona) Marcello Manfredi (University of Piemonte Orientale) Mauro Patrone (University of Piemonte Orientale) Elisa Robotti (University of Piemonte Orientale) Scientific committee: Marco Bagnati (Azienda Ospedaliera Universitaria Novara) Donatella Caruso (University of Milano) Daniela Cecconi (University of Verona) Marisa Gariglio (University of Piemonte Orientale) Fulvio Magni (University of Milano Bicocca) Marcello Manfredi (University of Piemonte Orientale) Claudio Santoro (University of Piemonte Orientale)

9 Accomodations: The following hotels are 10 minutes by walk to the campus. A discount is available for conference and school attenders, please ask it while booking the room. HOTEL CAVOUR NOVARA Via San Francesco d'assisi, Novara Tel. [+39] info@hotelcavournovara.com Website: HOTEL RESIDENCE MATTEOTTI Largo Buscaglia, 11/A Novara Tel: ; hrmatteottinovara@gmail.com Website: ALBERGO ITALIA Via Paolo Solaroli, 8, Novara Tel.: info@albergoitalia.novara.it Website: ALBERGO RISTORANTE PARMIGIANO Via Cattaneo, Novara Tel parmigiano@novara.com Website: HOTEL LA BUSSOLA Via Guido Boggiani, Novara (NO) Tel bussola@labussolanovara.it Website:

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