ASMS 2018 Press Conference

Transcription

1 ASMS 2018 Press Conference June 4, 2018 Victoria Wadsworth-Hansen Global Director Public Relations Agilent Technologies

2 Safe Harbor This presentation contains forward-looking statements (including, without limitation, information and future guidance on the company s goals, priorities, revenues, operating profit and operating margin, expected cash flow, growth opportunities, customer service and innovation plans, new product introductions, financial condition and considerations, earnings, share repurchases, dividends, ability to access capital markets, the continued strengths and expected growth of the markets the company sells into, operations, operating earnings, and tax rates) that involve risks and uncertainties that could cause results of Agilent to differ materially from management s current expectations. The words anticipate, plan, estimate, expect, intend, will, should forecast project and similar expressions, as they relate to the company, are intended to identify forward-looking statements. In addition, other risks that the company faces in running its operations include the ability to execute successfully through business cycles; the ability to successfully adapt its cost structures to continuing changes in business conditions; ongoing competitive, pricing and gross margin pressures; the risk that our strategic and cost-cutting initiatives will impair our ability to develop products and remain competitive and to operate effectively; the impact of geopolitical uncertainties on our markets and our ability to conduct business; the impact of currency exchange rates on our financial results; the ability to improve asset performance to adapt to changes in demand; the ability to successfully introduce new products at the right time, price and mix, and other risks detailed in the company's filings with the Securities and Exchange Commission, including our quarterly report on Form 10-Q for the year ended January 31, The company assumes no obligation to update the information in these presentations. These presentations and the Q&A that follows include non-gaap measures. Non-GAAP measures exclude primarily the impacts of acquisition and integration costs, transformation initiatives, and non-cash intangibles amortization. We also exclude any tax benefits that are not directly related to ongoing operations and which are either isolated or is not expected to occur again with any regularity or predictability, including the impact of Tax Reform. Most of these excluded amounts pertain to events that have not yet occurred and are not currently possible to estimate with a reasonable degree of accuracy. Accordingly, no reconciliation to GAAP amounts has been provided.

3 ASMS 2018 Press Conference Monty Benefiel Vice President/General Manager Mass Spectrometry Division

4 Agilent Saturday Innovation Symposium Saturday, June 2, 5:00 9:30 p.m. Manchester Grand Hyatt, San Diego Keynote: Metabolomics Analysis for Confirmation of Proteomics Insights Jenny van Eyk, Ph.D., Cedars-Sinai Medical Center High Productivity Growth Without Chaos: My Agilent Experience New Advances in CE-MS: Improving Sample Throughput and Data Quality for Large-scale Metabolite Profiling Applications High-throughput Quantitative Proteomics and Metabolomics for Biomanufacturing Research Carlos Sepúlveda General Manager, Agrolab Philip Britz-McKibbin, Ph.D. McMaster University Christopher J. Petzold, Ph.D. Lawrence Berkeley National Laboratory

5 ASMS 2018: More Donations to Make a Difference A Difference that Conferees Appreciated! $50,000 Donation Conferees can cast their vote in the Hospitality Suite

6 Innovation with Purpose 2017 New Mass Spec Introductions 6495B ifunnel LC/TQ InfinityLab LC/MSD (SQ) 6545XT AdvanceBio LC/Q-TOF 7250 GC/Q-TOF Ultivo LC/TQ ifunnel sensitivity, scan speed, fast polarity switching, MRMs and no-vent maintenance Stackable design with ESI, AJS, APCI, APPI and multi-mode ion sources Q-TOF optimized for large molecule analysis. AssayMAP sample prep and BioConfirm software complete biopharma workflows High resolution accurate mass Q-TOF with low-energy ionization - the only available system of its kind LC/MS innovations that reduce downtime and improve data quality & performance

7 Making Pain Points Go Away Downtime Data Management Lab Congestion Workflow Optimization System Complexity Increased Throughput Pain Points Specs Resolution Detection Limit Mass Range Scan Speed Minimum Dwell Polarity Switching MRM/sec Mass Accuracy

8 in no va tion (noun) something new or different introduced with pur pose (noun) the reason for which something exists or is done, made, used, etc.

9 Ultivo Awards Ultivo Recognized as the Most Innovative LC/TQ in 2017 Innovation Award from The Analytical Scientist theanalyticalscientist.com Best New Spectroscopy Product Scientists Choice Awards IBO Company of the Year Ultivo a contributing factor

10 Carlos Sepulveda Dirección General

11 Ultivo Triple Quad LC/MS Infinity II HPLC Stack 32 cm 12.6 in Ultivo Triple Quad 39 cm 15.4 in 79 cm 31.1 in

12 Ultivo Triple Quad LC/MS In a laboratory full of much larger MS systems.... can anything this small have performance that meets method requirements? 32 cm 12.6 in 39 cm 15.4 in 79 cm 31.1 in

13 Ultivo Innovations: Space-saving, sensitive, robust & reliable VacShield Ultivo Hyperbolic Quadrupole Assembly Virtual Pre/Post-Filters Intelligent Diagnostics Jet Stream Ion Source Cyclone Ion Guide Vortex Collision Cell

14 Ultivo New Applications Food Clinical Research Environmental TROCs in Drinking Water PFASs in Drinking Water Microcystins and Nodularin in Drinking Water EN Robustness > 1,500 injections of avocado extract 10 pesticides (5 ng/g 100 ng/g) QC Levels 10 ng/g, 15 ng/g, 20 ng/g < 5% peak area RSD s Vet Drugs in Pork and Hen Eggs Mycotoxins in Food Matrices Synthetic Fentanyls in Serum and Urine Testosterone in Serum Anti-epileptic Drugs in Serum

15 Ultivo: Now with Extra Flexibility New InfinityLab Flex Bench Dynamically reconfigure the lab Ultivo slides out for easy access Quiet Cover for Rough Pump

16 Stackable with 1260 or 1290 Infinity II LC InfinityLab LC/MSD OpenLAB CDS ChemStation edition Walkup, mass-based purification, 2D-LC, CE, and more OpenLAB CDS 2.0 Pharma compliance Next generation CDS features ESI, AJS, APCI, APPI & multimode ion sources

17 Peter Van Eenoo DoCoLab, WADA Certified This is amazing, especially if you consider the huge advantage of having accurate mass, full scan mass spectrometric data, which has unrivalled diagnostic value and allows retrospective data-analysis for unknown new compounds. That means one has the most flexible system, meeting the highest possible standards in a single instrument. Exactly, what we need!

18 Reduced total GC analysis time by: a factor of 2 Increased rate of positive detections: ~ 36% Intuvo GC/MS/MS Lowered concentration limits: 5x

19 Innovation with Purpose 2017 New Software Introductions MassHunter Quant B.09 Quant-My-Way MassHunter Walkup C MassHunter BioConfirm B.09 SureMass OpenLab 2.3 MassHunter Profinder B Simplified user interface is easily customized to make workflows more productive Mass based Fraction Collection Remote sample submission Intact protein analysis Peptide mapping Released glycan ID PDF reporting Increased dynamic range for GC/Q-TOF quantitation Enriched mass information for chromatography - MS base peak m/z labelling and MS peak purity Improved data processing with Retention Time Alignment

20 Quant-My-Way: Simplified UI Custom Button New Batch and Add Samples Available on all triple quad systems (not just Ultivo) Load Method Analyze and Report

21 Tell BioConfirm how you prepared the sample; then collect the report! BioConfirm BioPharma Workflows MS expertise NOT required! Answer five questions about your sample Press the green button BioConfirm will tell you how well the protein was confirmed, along with reports and results

22 Thomas J. McLellan Senior Scientist, Pfizer Inc. Structural and Molecular Science Intact proteins (up to 230kDa) - Including membrane proteins UHPLC with up to 8 columns High-resolution/accurate mass Q-TOF 32 non-mass spectrometrists - Multiple departments Walkup software for analysis BioConfirm for data review - 5 copies of BioConfirm running on shared server

23 Easy to train and easy to support Thomas Increased J. McLellan group productivity Senior Scientist, Pfizer Inc. Structural and Molecular Science Intact proteins (up to 230KDa) - Including membrane proteins 32 non-mass spectrometrists - Multiple departments UHPLC with up to 8 columns Just routine, just routine Walkup software for analysis Running robustly since July High-resolution/accurate mass BioConfirm for data review Q-TOF - 5 copies of BioConfirm running on shared server

24 What s Next Continued Innovation - Investment in R&D Customer Additional Capabilities - Complementary M&A Leveraging Combined Agilent Expertise